Wright's stain is a histologic stain that facilitates the differentiation of blood cell types. Histology (from the Greek = 'tissue' is the study of the microscopic anatomy of cells and tissues of Plants and A blood cell (also called blood corpuscle) is any cell of any type normally found in Blood. It is used primarily to stain peripheral blood smears and bone marrow aspirates which are examined under a light microscope. A Blood Film or Peripheral Blood Smear is a slide made from a drop of Blood, that allows the cells to be examined microscopically Bone marrow is the flexible tissue found in the hollow interior of Bones In adults marrow in large bones produces new Blood cells It constitutes 4% of "FNA" redirects here For the botanical book series see Flora of North America North of Mexico. The optical microscope, often referred to as the "light microscope" is a type of Microscope which uses Visible light and a system of lenses to In cytogenetics it is used to stain chromosomes to facilitate diagnosis of syndromes and diseases. Cytogenetics is a branch of Genetics that is concerned with the study of chromosomes and cell division
It is named for James Homer Wright, who devised the stain, a modification of the Romanowsky stain, in 1902. Dr James Homer Wright (1869&ndash1928 was an early and influential American Pathologist, who for many years was chief of pathology at Massachusetts General Romanowsky staining was a prototypical staining technique that was the forerunner of several distinct but similar methods including Giemsa, Jenner, Because it distinguishes easily between blood cells, it became widely used for performing differential white blood cell counts, which are routinely ordered when infections are expected, and as part of an assessment of overall health.
There are related stains known as the buffered Wright stain, the Wright-Giemsa stain, and the buffered Wright-Giemsa stain, and specific instructions depend on the solutions being used, which may include Eosin Y, Azure B, and Methylene Blue (some commercial preparations combine solutions to simplify staining). Eosin is a Fluorescent red Dye resulting from the action of Bromine on Fluorescein. Methylene blue is a heterocyclic aromatic Chemical compound with Molecular formula: C 16 H 18 Cl[[nitrogen The May-Grünwald stain, which produces a more intense coloration, also takes a longer time to perform.
White blood cells stained with Wright's stain:
See also
External links
- Wright+stain at eMedicine Dictionary
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