Vasculogenesis is the process of blood vessel formation occurring by a de novo production of endothelial cells. The blood vessels are part of the Circulatory system and function to transport Blood throughout the body The endothelium is the thin layer of cells that line the interior surface of Blood vessels forming an interface between circulating Blood in the

Though similar to angiogenesis, the two are different in one aspect: the term angiogenesis denotes the formation of new blood vessels from pre-existing ones, while vasculogenesis is the term used for the formation of new blood vessels when there are no pre-existing ones. Angiogenesis is a physiological process involving the growth of new Blood vessels from pre-existing vessels For example, if a monolayer of endothelial cells begin sprouting to form capillaries, angiogenesis is occurring. A monolayer is a single closely packed layer of atoms molecules or cells The endothelium is the thin layer of cells that line the interior surface of Blood vessels forming an interface between circulating Blood in the Capillaries are the smallest of a body's Blood vessels measuring 5-10 μm in diameter which connect Arterioles and Venules and enable the interchange Vasculogenesis, in contrast, first believed to occur only during embryologic development, is the term for when endothelial precursor cells (angioblasts) migrate and differentiate in response to local cues (such as growth factors and extracellular matrix) to form new blood vessels. Blood vessels first make their appearance in several scattered vascular areas that are developed simultaneously between the Entoderm and the Mesoderm of the Yolk-sac These vascular trees are then pruned and extended through angiogenesis. Recently, however, it was realized that vasculogenesis can also occur in the adult organism. Circulating endothelial progenitor cells (derivatives of stem cells) were identified and reportedly able to contribute, albeit to varying degrees, to neovascularization, such as during tumor growth, or to the revascularization process following trauma, e. Endothelial progenitor cells are Bone marrow -derived cells that circulate in the blood and have the ability to differentiate into Endothelial cells, the cells that See also Cancer A tumor or tumour is the name for a swelling or lesion formed by an abnormal growth of cells (termed neoplastic g. after cardiac ischemia. In Medicine, ischemia ( Greek ισχαιμία, isch- is restriction hema or haema is Blood) is a restriction

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