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The Vadoma, also Wadoma (singular Mudoma) are a tribe living in the west of Zimbabwe, especially in the Urungwe and Sipolilo districts on the Zambezi river valley. See also Great Zimbabwe National Monument. For information about the March and June 2008 presidential elections see Zimbabwean presidential election The Zambezi (also spelled Zambesi) is the fourth-longest River in Africa and the largest flowing into the Indian Ocean from Africa They have few contacts with the Bantu majority.

A substantial majority of this tribe has a condition known as ectrodactyly in which the middle three toes are absent and the two outer ones are turned in, resulting in the tribe being known as the "two toed" or "ostrich footed" tribe. Ectrodactyly, commonly known as lobster claw syndrome   sometimes known as Karsch-Neugebauer syndrome, is a rare Congenital deformity of the hand where This is an autosomal dominant condition resulting from a single mutation on chromosome number seven. A chromosome is an organized structure of DNA and Protein that is found in cells. It is reported that those with the condition are not handicapped and well integrated into the tribe. Indeed it may help in tree climbing. The Kalanga of the Kalahari desert also have a number of members with ectrodactyly, and may be related. Kalanga may refer to Ikalanga language Kalanga Togo

The Vadoma are a popular example of the genetic effects of small population size on genetic defects and mutation. Populations with small population size behave differently to larger populations A genetic disorder is a condition caused by abnormalities in Genes or Chromosomes While some diseases such as Cancer, are due to genetic abnormalities acquired Due to the Vadoma tribe's isolation, they have developed and maintained ectrodactyly, and due to the comparatively small gene pool, the condition is much more frequent than elsewhere.

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