Thelarche is the first stage of secondary (postnatal) breast development, usually occurring at the beginning of puberty in girls. The breast is the upper Ventral region of an animal’s Torso, particularly that of Mammals including Human beings. Thelarche is usually noticed as a firm, tender lump directly under the center of the nipple (papilla and areola). In its most general form a nipple is a Structure from which a fluid emanates This aritcle is about the breast tissue For the Entomology term see Glossary of Lepidopteran_terms#Wings. Thelarche is also referred to as a "breast bud", or more formally as Tanner stage 2 breast development (Tanner stage 1 being the entirely undeveloped prepubertal state). The Tanner stages (also known as the Tanner scale) are stages of physical development in Children, Adolescents and Adults The stages Thelarche may occur on one side first, or both sides simultaneously.
Thelarche is the first physical change of puberty in about 60% of girls, and is a result of rising levels of estradiol. Estradiol (17β-estradiol (also oestradiol) is a Sex hormone. It is typical for a woman's breasts to be unequal in size, particularly while the breasts are developing. Statistically it is slightly more common for the left breast to be the larger. [1] In rare cases, the breasts may be significantly different in size, or one breast may fail to develop entirely.
Although breast development can occur as a part of normal male puberty, it is termed gynecomastia, and the term "thelarche" is not used with reference to male breast development. Gynecomastia, or gynaecomastia, ˌgaɪnəkoʊˈmæstiə is the development of abnormally large Mammary glands in Males resulting in breast enlargement which
When thelarche occurs at an unusually early age, it may be the first manifestation of precocious puberty. Precocious puberty (La pubertas praecox) is an unusually early onset of Puberty, the process of sexual maturation triggered by the brain or exogenous chemicals which If no other changes of puberty or sex hormone effects occur, it is referred to as isolated premature thelarche, and needs no treatment. Sex steroids, also known as gonadal steroids, are Steroid hormones that interact with Vertebrate Androgen or Estrogen receptors
Premature thelarche is a benign, self-limiting condition which is characterised by breast development with no other signs of sexual maturation.
There may well be two types of premature thelarche.
The classical type commences during the first year of life and tends to resolve by the age of 2.
There is a second form of premature thelarche, of which the age of onset is over 2 years of age and this tends to be more persistent and with a higher incidence of uterine bleeding.