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Suppressor of variegation 4-20 homolog 1 (Drosophila)
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| Identifiers | ||
| Symbol(s) | SUV420H1; CGI-85; MGC118906; MGC118909; MGC21161; MGC703 | |
| External IDs | MGI: 2444557 HomoloGene: 32351 | |
| RNA expression pattern | ||
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| Orthologs | ||
| Human | Mouse | |
| Entrez | 51111 | 225888 |
| Ensembl | ENSG00000110066 | ENSMUSG00000045098 |
| Refseq | NM_016028 (mRNA) NP_057112 (protein) |
NM_144871 (mRNA) NP_659120 (protein) |
| Location | Chr 11: 67.68 - 67.74 Mb | Chr 19: 3.77 - 3.82 Mb |
| Pubmed search | [1] | [2] |
Suppressor of variegation 4-20 homolog 1 (Drosophila), also known as SUV420H1, is a human gene. The Human Genome Organisation (HUGO is an organization involved in the Human Genome Project, a project about mapping the human genome The Mouse Genome Informatics (MGI website is run by The Jackson Laboratory. HomoloGene, a tool of the National Center for Biotechnology Information (NCBI is a system for automated detection of homologs (similarity attributable to descent The Entrez Global Query Cross-Database Search System is a powerful Federated search engine or Web portal that allows users to search many discrete Health sciences Ensembl is a joint scientific project between the European Bioinformatics Institute and the Wellcome Trust Sanger Institute, which was launched in 1999 in response to the imminent PubMed is a free search engine for accessing the MEDLINE database of citations and abstracts of biomedical research articles History See also History of genetics The existence of genes was first suggested by Gregor Mendel (1822-1884 who in the 1860s studied inheritance [1]
This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Two alternatively spliced transcript variants have been found for this gene. [1]
References
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. ". Gene 138 (1-2): 171-4. PMID 8125298.
- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery. ". Genome Res. 6 (9): 791-806. PMID 8889548.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. ". Gene 200 (1-2): 149-56. PMID 9373149.
- Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. ". Genome Res. 10 (5): 703-13. PMID 10810093.
- Twells RC, Metzker ML, Brown SD, et al. (2001). "The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13. ". Genomics 72 (3): 231-42. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 11401438.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ". Proc. Natl. Acad. Sci. U. S. A. 99 (26): 16899-903. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs. ". Nat. Genet. 36 (1): 40-5. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ". Genome Res. 14 (10B): 2121-7. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 15489334.
- Tryndyak VP, Kovalchuk O, Pogribny IP (2006). "Loss of DNA methylation and histone H4 lysine 20 trimethylation in human breast cancer cells is associated with aberrant expression of DNA methyltransferase 1, Suv4-20h2 histone methyltransferase and methyl-binding proteins. ". Cancer Biol. Ther. 5 (1): 65-70. PMID 16322686.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry. ". Mol. Syst. Biol. 3: 89. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 17353931.
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