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Proparacaine | |
| Systematic (IUPAC) name | |
| 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate | |
| Identifiers | |
| CAS number | |
| ATC code | N01 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C16H26N2O3 |
| Mol. mass | 294. IUPAC Nomenclature is a system of naming Chemical compounds and of describing the science of Chemistry in general CAS registry numbers are unique numerical identifiers for Chemical compounds Polymers biological sequences mixtures and Alloys They are also referred to The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs It is controlled by the WHO Collaborating Centre for Drug A section of the Anatomical Therapeutic Chemical Classification System. PubChem is a Database of chemical Molecules The system is maintained by the National Center for Biotechnology Information (NCBI a component The DrugBank database available at the University of Alberta is a unique Bioinformatics and Cheminformatics resource that combines detailed drug (i A chemical formula is a way of expressing information about the Atoms that constitute a particular Chemical compound, and how the relationship between those atoms changes Carbon (kɑɹbən is a Chemical element with the symbol C and its Atomic number is 6 Hydrogen (ˈhaɪdrədʒən is the Chemical element with Atomic number 1 Nitrogen (ˈnaɪtɹəʤɪn is a Chemical element that has the symbol N and Atomic number 7 and Atomic weight 14 Oxygen (from the Greek roots ὀξύς (oxys (acid literally "sharp" from the taste of acids and -γενής (-genēs (producer literally begetteris the The molecular mass (abbreviated m of a substance, more commonly referred to as molecular weight and abbreviated as MW, is the Mass of one 389 g/mol |
| Pharmacokinetic data | |
| Bioavailability | n/a |
| Metabolism | plasma |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. | C(US) |
| Legal status | |
| Routes | Topical |
Proparacaine (Alcaine, Ak-Taine) is a topical anesthetic drug of the amino ester group. In Pharmacology, bioavailability is used to describe the fraction of an administered Dose of unchanged drug that reaches the Systemic circulation, one of Drug metabolism is the Metabolism of drugs, their Biochemical modification or degradation usually through specialized enzymatic systems The biological half-life of a substance is the time it takes for a substance (drug radioactive nuclide or other to lose half of its pharmacologic physiologic or radiologic activity Excretion is the process of eliminating waste products of Metabolism and other non-useful materials The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical if it is used as directed by the mother during The United States of America —commonly referred to as the The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction In Pharmacology and Toxicology, a route In Medicine, a topical Medication is applied to body surfaces such as the Skin or Mucous membranes for example the Vagina A topical anesthetic is a Local anesthetic that is used to numb the surface of a body part It is indicated for use as an ophthalmic anesthetic, to reduce pain and discomfort during procedures involving the eye. Proparacaine is available as its hydrochloride salt in ophthalmic solutions at a concentration of 0. 5%. It is believed the drug exerts an effect on voltage gated sodium channels (as an antagonist) to affect the permeability of neuronal membranes; how this inhibits pain sensations and the exact mechanism of action of proparacaine are, however, unknown. Sodium channels are Integral membrane proteins that form Ion channels, conducting sodium ions ( Na+) through a cell's Plasma membrane An antagonist (from Greek ανταγωνιστής - antagonistes, "opponent competitor rival" is a character or
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