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PiHKAL: A Chemical Love Story

Cover of PiHKAL, 1st ed.
Author Alexander and Ann Shulgin
Country United States
Subject(s) Pharmacology, Autobiography, Psychoactive drugs
Publisher Transform Press
Publication date 1991
Media type Paperback
ISBN ISBN 0-9630096-0-5
Followed by TiHKAL

PiHKAL is a 1991 book by Dr. Alexander "Sasha" Shulgin (born June 17 1925 in Berkeley, California) is a Russian-American Pharmacologist, Chemist and Ann Shulgin (born March 22, 1931) is an author and the wife of famous chemist Alexander Shulgin. The United States of America —commonly referred to as the Pharmacology (from Greek grc φάρμακον pharmakon, "drug" and grc -λογία -logia) is the study of how Drugs An autobiography, from the Greek αὐτός autos "self" βίος bios "life" and γράφειν graphein "to write" A psychoactive drug or psychotropic substance is a Chemical substance that acts primarily upon the Central nervous system where it alters Brain Publishing is the process of production and dissemination of Literature or Information &ndash the activity of making information available for public view TiHKAL is a 1997 book written by Alexander Shulgin and Ann Shulgin about a family of Psychoactive drugs known as Tryptamines A sequel Alexander Shulgin and Ann Shulgin about psychedelic phenethylamines. Alexander "Sasha" Shulgin (born June 17 1925 in Berkeley, California) is a Russian-American Pharmacologist, Chemist and Ann Shulgin (born March 22, 1931) is an author and the wife of famous chemist Alexander Shulgin. Modern psychedelia For "psychedelics" see Psychedelic drug. Phenethylamine, or β -phenylethylamine or 2-phenylethylamine is an Alkaloid and Monoamine. The full title of the book is Phenethylamines i Have Known And Loved: A Chemical Love Story.

The book is arranged in two parts. The first part is a fictionalized autobiography of the couple. The second part contains detailed synthesis instructions for over 200 psychedelic compounds (most of which Shulgin personally invented), including dosages, subjective experiences, and other commentary.

Shulgin's choices of synthesis procedures in the second half of the book are themselves perhaps a small act of subversion: While the reactions are beyond the ability of people with no chemistry education, they tend to emphasize techniques that do not require difficult to obtain chemicals. Notable among these are the use of mercury-aluminum amalgam (an unusual but easy to obtain reagent) as a reducing agent and detailed suggestions on legal plant sources of important drug precursors such as safrole. Aluminium amalgam is a Solution of Aluminium in mercury A reagent or reactant is a substance or compound consumed during a Chemical reaction. A reducing agent (also called a reductant or reducer) is the element or a compound in a Redox (reduction-oxidation reaction (see Electrochemistry Safrole is a colorless or slightly yellow oily liquid It is typically extracted from the root-bark or the fruit of Sassafras plants in the form of Sassafras oil,

Contents

Impact

Through PiHKAL (and later, TiHKAL) Shulgin sought to ensure that his discoveries would escape the limits of professional research labs and find their way to the public; a goal consistent with his stated beliefs that psychedelic drugs can be valuable tools for self-exploration. TiHKAL is a 1997 book written by Alexander Shulgin and Ann Shulgin about a family of Psychoactive drugs known as Tryptamines A sequel Psychedelic drugs are Psychoactive drugs whose primary action is to alter the thought processes of the brain and perception of the mind The MDMA (ecstasy) synthesis published in PiHKAL remains one of the most common clandestine methods to this day. MDMA ( 34-methylenedioxy- N -methylamphetamine) most commonly known today by the street name Ecstasy (often abbreviated E, X, Clandestine chemistry generally refers to Chemistry carried out in illegal drug Laboratories (known colloquially as labs) but can include any However, many countries saw these chemicals as dangerous and banned the major ones such as 2C-B, 2C-T-2, and 2C-T-7. 2C-B or 4-bromo-25-dimethoxyphenethylamine is a psychedelic drug of the 2C family, an entactogen. 2C-T-2, or 25-di Methoxy -4- Ethyl[[thio]][[phenethylamine]], is a Psychedelic and Entheogenic Phenethylamine of the 2C-T-7 is a Hallucinogenic Phenethylamine of the 2C family. In his book PiHKAL (Phenethylamines i Have Known And Loved, In the United Kingdom, all of the drugs of PiHKAL are illegal. The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom, the UK or Britain,is a Sovereign state located

DEA Raid

In 1994, two years after the publication of PiHKAL, the United States DEA raided Shulgin's lab. The Drug Enforcement Administration ( DEA) is a United States Department of Justice Law enforcement agency tasked with combating drug smuggling and Finding problems with his record keeping, the DEA requested that Shulgin turn over his DEA license (which allowed him to work with and possess otherwise illicit substances), and he was fined US$25,000 for the possession of anonymous samples which had been sent to him for quality testing. Prior to the publication of PiHKAL, during the 15 years in which Shulgin held his license, there were two unannounced reviews of the lab; both failed to find any irregularities. Richard Meyer, spokesman for DEA's San Francisco Field Division, has stated that "It is our opinion that those books are pretty much cookbooks on how to make illegal drugs. Agents tell me that in clandestine labs that they have raided, they have found copies of those books," suggesting to many that the publication of PiHKAL and the termination of Shulgin's license were related. [1]

Essential Amphetamines

The "Essential Amphetamines" are what Shulgin describes as the "ten essential oils that have a three carbon chain, and each lacks only a molecule of ammonia to become an amphetamine" (PiHKAL Entry #157 TMA). The list consists of:

It should be noted that not all of these are chemicals tested in PiHKAL; some are just mentioned. PMA ( para Methoxy[[amphetamine]], p-methoxyamphetamine' or 4-methoxyamphetamine) is a synthetic Phenethylamine DMA, or di Methoxy[[amphetamine]], is a series of lesser-known psychedelic drugs similar in structure to Amphetamine and to Trimethoxyamphetamine DMA, or di Methoxy[[amphetamine]], is a series of lesser-known psychedelic drugs similar in structure to Amphetamine and to Trimethoxyamphetamine 34-Methylenedioxyamphetamine ( MDA or Tenamfetamine) is a Psychedelic hallucinogenic drug and empathogen/entactogen of the MMDA, or 3- Methoxy -45- Methylenedi[[oxygen oxy]] Amphetamine, is a Stimulant, a Psychedelic drug an Entheogen MMDA, or 3- Methoxy -45- Methylenedi[[oxygen oxy]] Amphetamine, is a Stimulant, a Psychedelic drug an Entheogen MMDA, or 3- Methoxy -45- Methylenedi[[oxygen oxy]] Amphetamine, is a Stimulant, a Psychedelic drug an Entheogen TMAs, also known as trimethoxyamphetamines, are a family of Isomeric Psychedelic hallucinogenic drugs. TMAs, also known as trimethoxyamphetamines, are a family of Isomeric Psychedelic hallucinogenic drugs. DMMDA, or 25-di Methoxy -34-methylenedioxy Amphetamine, is a lesser-known psychedelic drug and a Substituted Amphetamine. DMMDA-2 is a Psychedelic Phenethylamine discussed by Alexander Shulgin in his book PiHKAL (Phenethylamines i Have Known And Loved Tetramethoxyamphetamine, or 2345-tetra Methoxy[[amphetamine]], is a lesser-known psychedelic drug and a Substituted amphetamine.

Magical Half-Dozen

The so-called 'magical half-dozen' refers to Shulgin's self-rated most important phenethylamine compounds, all of which except mescaline were developed and synthesized by himself. They are found within the first book of PiHKAL, and are as follows:

Contents

See also

Notes

  1. ^ Bennett, Drake. "Dr. Ecstasy", New York Times Magazine, New York Times, 2005-01-30. Year 2005 ( MMV) was a Common year starting on Saturday (link displays full calendar of the Gregorian calendar. Events 1648 - Eighty Years' War: The Treaty of Münster is signed ending the conflict between the Netherlands and Spain Retrieved on 2006-07-08. Year 2006 ( MMVI) was a Common year starting on Sunday of the Gregorian calendar. Events 939 - The Major Occultation or Ghaybat el-Kubra of Muhammad al-Mahdi 1099 - First Crusade: 15000 (English) 

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