A phagolysosome is a membrane-enclosed organelle which is formed from the fusing of a lysosome and a phagosome. In Cell biology, an organelle (pronunciation /ɔː(rgəˡnɛl/ is a specialized subunit within a cell that has a specific function and is usually separately enclosed Lysosomes are Organelles that contain Digestive enzymes (acid Hydrolases. In cell biology a phagosome is a Vacuole formed around a particle absorbed by Phagocytosis. This process of phagolysosome formation is common in immunological functions of macrophages. Macrophages ( Greek: "big eaters" from makros "large" + phagein "eat" ( Mø) are cells within the tissues that