Oxaloacetic acid
IUPAC name	Oxobutanedioic acid
Other names	Oxaloacetic acid Oxalacetic acid Oxosuccinic acid
Identifiers
CAS number	[328-42-7]
EINECS number	206-329-8
SMILES	OC(C(CC(O)=O)=O)=O
Properties
Molecular formula	C4H4O5
Molar mass	132. IUPAC Nomenclature is a system of naming Chemical compounds and of describing the science of Chemistry in general CAS registry numbers are unique numerical identifiers for Chemical compounds Polymers biological sequences mixtures and Alloys They are also referred to The EINECS number (for European Inventory of Existing Chemical Substances) is a registry number given to each Chemical substance commercially available in the A chemical formula is a way of expressing information about the Atoms that constitute a particular Chemical compound, and how the relationship between those atoms changes Molar mass, symbol M, is the Mass of one mole of a substance ( Chemical element or Chemical compound) 07 g/mol
Density	? g/cm3
Melting point	161 °C
Thermochemistry
Std enthalpy of formation ΔfHo298	-943. The density of a material is defined as its Mass per unit Volume: \rho = \frac{m}{V} Different materials usually have different The melting point of a solid is the temperature range at which it changes state from solid to Liquid. The standard enthalpy of formation or "standard heat of formation" of a compound is the change of Enthalpy that accompanies the formation of 1 mole of a 21 kJ/mol
Std enthalpy of combustion ΔcHo298	-1205. The standard enthalpy of combustion is the Enthalpy change when one mole of a substance completely reacts with oxygen under standard thermodynamic conditions (although 58 kJ/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Oxaloacetic acid is an organic compound with the chemical formula HO₂CC(O)CH₂CO₂H. In Chemistry, the standard state of a material is its state at 1 bar (100 Kilopascals exactly An organic compound is any member of a large class of Chemical compounds whose Molecules contain Carbon. It also has other names (see Table) and its conjugate base is called "oxaloacetate. Within the Brønsted - Lowry ( protonic) theory of acids and bases, a conjugate acid is the acid member HX of a pair of two compounds that transform " This four-carbon dicarboxylic acid is a protonated variant of oxaloacetate, which is an intermediate of the citric acid cycle and gluconeogenesis. Carbon (kɑɹbən is a Chemical element with the symbol C and its Atomic number is 6 Dicarboxylic acids are Organic compounds that are substituted with two Carboxylic acid Functional groups In molecular formulae for dicarboxylic acids these The citric acid cycle, also known as the tricarboxylic acid cycle ( TCA cycle) or the Krebs cycle, (or rarely the Szent-Györgyi–Krebs cycle Gluconeogenesis (abreviated GNG) is a Metabolic pathway that results in the generation of Glucose from non- Carbohydrate carbon substrates such Oxaloacetate forms upon oxidation of L-malate, catalysed by malate dehydrogenase, and reacts with Acetyl-CoA to form citrate, catalysed by citrate synthase. Redox (shorthand for reduction-oxidation reaction describes all Chemical reactions in which atoms have their Oxidation number ( Oxidation state Malic acid is an Organic compound with the formula HO2CCH2CHOHCO2H Malate dehydrogenase ( is an Enzyme in the Citric acid cycle that catalyzes the conversion of Malate into Oxaloacetate (using Acetyl-CoA is an important molecule in metabolism used in many biochemical reactions A citrate can refer either to the Conjugate base of Citric acid, (C3H5O(COO33&minus or to the Esters of citric The enzyme citrate synthase (EC 2331 4137 exists in nearly all living cells and stands as a pace-making enzyme in the first step of the Citric Acid Cycle (or Krebs Cycle It also forms in the mesophyll of plants by the condensation of CO₂ with phosphoenolpyruvate, catalysed by PEP Carboxykinase. In Botany, a leaf is an above-ground Plant organ specialized for Photosynthesis. Carbon dioxide ( Chemical formula:) is a Chemical compound composed of two Oxygen Atoms covalently bonded to a single Phosphoenolpyruvate (synonyms phosphoenolpyruvic acid, PEP) is an important Chemical compound in Biochemistry. Not to be confused with Phosphoenolpyruvate carboxylase, PEPC Phosphoenolpyruvate carboxykinase (or PEPCK) is an Enzyme It can arise from pyruvate via an anaplerotic reaction. Pyruvic acid (CH3COCO2H is an alpha-keto acid. The Carboxylate Anion of pyruvic acid is known as pyruvate. Anaplerotic reactions are those that form intermediates of the TCA or Citric acid cycle.

The enol forms of oxaloacetic acid are particularly stable, so much so that the two isomers have different melting points (152 °C cis, 184 °C trans). Enols (also known as alkenols) are Alkenes with a Hydroxyl group affixed to one of the carbon atoms composing the Double bond. The enol proton has a pK_a value of 13. 02. The enzyme fumarase A from E. coli catalyses the conversion between the keto and enol forms. Enzymes are Biomolecules that catalyze ( ie increase the rates of Chemical reactions Almost all enzymes are Proteins Fumarase (or fumarate hydratase) is an Enzyme involved in the Krebs Cycle (aka the Tricarboxylic Acid Cycle aka the Citric Acid Cycle that Catalyzes

Oxaloacetate is unstable in solution, decomposing to pyruvate by decarboxylation over a period of hours (room temperature) or days (0 °C). Decarboxylation is any Chemical reaction in which a Carboxyl group (-COOH is split off from a compound as Carbon dioxide (CO2 Refrigerated storage of the solid is therefore recommended.

Relationship of oxaloacetic acid, malic acid, and aspartic acid

References