Over-the-counter, also known as OTC, may refer to:
- Over-the-counter drug -- medicine that may be sold without a prescription and without a visit to a medical professional, in contrast to prescription drugs. Over-the-counter (OTC drugs are medicines that may be sold without a prescription, in contrast to Prescription drugs The name "over-the-counter"
- Over-the-counter (finance), financial instruments, such as stocks, exchanged directly between two parties. Over-the-counter ( OTC) trading is to Trade Financial instruments such as Stocks bonds, commodities or derivatives
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