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2'-5'-oligoadenylate synthetase-like
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| PDB rendering based on 1wh3. The Protein Data Bank ( PDB) is a repository for 3-D structural data of Proteins and Nucleic acids These data typically obtained by X-ray crystallography | ||
| Available structures: 1wh3 | ||
| Identifiers | ||
| Symbol(s) | OASL; TRIP14; p59OASL | |
| External IDs | OMIM: 603281 MGI: 2180849 HomoloGene: 2769 | |
| RNA expression pattern | ||
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| Orthologs | ||
| Human | Mouse | |
| Entrez | 8638 | 231655 |
| Ensembl | ENSG00000135114 | ENSMUSG00000041827 |
| Uniprot | Q15646 | n/a |
| Refseq | NM_003733 (mRNA) NP_003724 (protein) |
NM_145209 (mRNA) NP_660210 (protein) |
| Location | Chr 12: 119.94 - 119.96 Mb | Chr 5: 115.18 - 115.2 Mb |
| Pubmed search | [1] | [2] |
2'-5'-oligoadenylate synthetase-like, also known as OASL, is a human gene. The Human Genome Organisation (HUGO is an organization involved in the Human Genome Project, a project about mapping the human genome The Mouse Genome Informatics (MGI website is run by The Jackson Laboratory. HomoloGene, a tool of the National Center for Biotechnology Information (NCBI is a system for automated detection of homologs (similarity attributable to descent The Entrez Global Query Cross-Database Search System is a powerful Federated search engine or Web portal that allows users to search many discrete Health sciences Ensembl is a joint scientific project between the European Bioinformatics Institute and the Wellcome Trust Sanger Institute, which was launched in 1999 in response to the imminent UniProt is the uni versal prot ein resource a central repository of Protein data created by combining Swiss-Prot, TrEMBL PubMed is a free search engine for accessing the MEDLINE database of citations and abstracts of biomedical research articles History See also History of genetics The existence of genes was first suggested by Gregor Mendel (1822-1884 who in the 1860s studied inheritance [1]
References
Further reading
- Mackay V, Linn S (1976). "Selective inhibition of the dnase activity of the recBC enzyme by the DNA binding protein from Escherichia coli. ". J. Biol. Chem. 251 (12): 3716–9. PMID 776974.
- Lee JW, Choi HS, Gyuris J, et al. (1995). "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. ". Mol. Endocrinol. 9 (2): 243–54. PMID 7776974.
- Hartmann R, Olsen HS, Widder S, et al. (1998). "p59OASL, a 2'-5' oligoadenylate synthetase like protein: a novel human gene related to the 2'-5' oligoadenylate synthetase family. ". Nucleic Acids Res. 26 (18): 4121–8. PMID 9722630.
- Rebouillat D, Marié I, Hovanessian AG (1998). "Molecular cloning and characterization of two related and interferon-induced 56-kDa and 30-kDa proteins highly similar to 2'-5' oligoadenylate synthetase. ". Eur. J. Biochem. 257 (2): 319–30. PMID 9826176.
- Hovnanian A, Rebouillat D, Levy ER, et al. (1999). "The human 2',5'-oligoadenylate synthetase-like gene (OASL) encoding the interferon-induced 56-kDa protein maps to chromosome 12q24. 2 in the proximity of the 2',5'-OAS locus. ". Genomics 56 (3): 362–3. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 10087211.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ". Proc. Natl. Acad. Sci. U. S. A. 99 (26): 16899–903. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs. ". Nat. Genet. 36 (1): 40–5. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 14702039.
- Andersen JB, Strandbygård DJ, Hartmann R, Justesen J (2004). "Interaction between the 2'-5' oligoadenylate synthetase-like protein p59 OASL and the transcriptional repressor methyl CpG-binding protein 1. ". Eur. J. Biochem. 271 (3): 628–36. PMID 14728690.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ". Genome Res. 14 (10B): 2121–7. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 15489334.
- Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12. ". Nature 440 (7082): 346–51. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 16541075.
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