Negative selection may refer to:
- In biology:
- Negative selection (natural selection), in natural selection it refers to the selective removal of rare alleles that are deleterious. Negative selection, in Natural selection, is the selective removal of Alleles that are deleterious.
- Negative selection (artificial selection), in artificial selection it refers to where negative, rather than positive, traits of a species are selected for. In Artificial selection, negative selection is where negative rather than positive traits of a species are selected for evolutionary continuance
- In politics:
- Negative selection (politics), is a process that occurs in rigid hierarchies, most notably dictatorships. Negative selection, in Politics, is a process that occurs in rigid hierarchies, most notably Dictatorships The person on the top of the hierarchy wishing
- In immunology:
- Negative selection (immunology) T-cells that recognize self MHC molecules (and peptides) with high affinity are deleted from the repertoire of cells. Central_tolerance is produced. Central tolerance is the mechanism by which newly developing T cells and B cells are rendered non-reactive to self Avoids auto-immunity. Occurs after positive selection.
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