| N-Acetylglucosamine | |
|---|---|
| IUPAC name | 2-(Acetylamino)-2-deoxy-D-glucose |
| Other names | N-Acetyl-D-Glucosamine GlcNAc NAG |
| Molecular formula | C8H15NO6 |
| Identifiers | |
| CAS number | [7512-17-6] |
| PubChem | |
| SMILES | [H][C@](C([H])(CO)O[C@@](O) ([H])[C@@](NC(C)=O)1[H])(O)[C@@]1(O)[H] |
| Properties | |
| Molar mass | 221. IUPAC Nomenclature is a system of naming Chemical compounds and of describing the science of Chemistry in general A chemical formula is a way of expressing information about the Atoms that constitute a particular Chemical compound, and how the relationship between those atoms changes CAS registry numbers are unique numerical identifiers for Chemical compounds Polymers biological sequences mixtures and Alloys They are also referred to PubChem is a Database of chemical Molecules The system is maintained by the National Center for Biotechnology Information (NCBI a component Molar mass, symbol M, is the Mass of one mole of a substance ( Chemical element or Chemical compound) 21 |
| Melting point |
211 |
| Hazards | |
| S-phrases | S24/25 |
| Related compounds | |
| Related Monosaccharides | N-Acetylgalactosamine |
| Related compounds | Glucosamine Glucose |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
|
N-Acetylglucosamine (N-Acetyl-D-Glucosamine, or GlcNAc, or NAG) is a monosaccharide derivative of glucose. The melting point of a solid is the temperature range at which it changes state from solid to Liquid. S-phrases are defined in Annex IV of European Union Directive 67/548/EEC: Safety advice concerning dangerous substances and preparations. S-phrases are defined in Annex IV of European Union Directive 67/548/EEC: Safety advice concerning dangerous substances and preparations. N-Acetylgalactosamine (also called GalNAc, 2-Acetamido-2-deoxy-D-galactopyranose or N-Acetyl-D-galactosamine) is a Monosaccharide derivative Glucosamine (C6H13NO5 is an Amino sugar and a prominent precursor in the Biochemical synthesis of glycosylated proteins Glucose (Glc a Monosaccharide (or simple Sugar) also known as grape sugar, is an important Carbohydrate in Biology. In Chemistry, the standard state of a material is its state at 1 bar (100 Kilopascals exactly Monosaccharides (from Greek monos: single sacchar: sugar are the most basic unit of Carbohydrates They consist of one sugar and Glucose (Glc a Monosaccharide (or simple Sugar) also known as grape sugar, is an important Carbohydrate in Biology. Chemically it is an amide between glucosamine and acetic acid. Glucosamine (C6H13NO5 is an Amino sugar and a prominent precursor in the Biochemical synthesis of glycosylated proteins Acetic acid, also known as ethanoic acid, is an organic chemical compound, giving Vinegar its sour taste It has a molecular formula of C8H15NO6, a molar mass of 221. Carbon (kɑɹbən is a Chemical element with the symbol C and its Atomic number is 6 Hydrogen (ˈhaɪdrədʒən is the Chemical element with Atomic number 1 Nitrogen (ˈnaɪtɹəʤɪn is a Chemical element that has the symbol N and Atomic number 7 and Atomic weight 14 Oxygen (from the Greek roots ὀξύς (oxys (acid literally "sharp" from the taste of acids and -γενής (-genēs (producer literally begetteris the Molar mass, symbol M, is the Mass of one mole of a substance ( Chemical element or Chemical compound) 21 g/mol, and it is significant in several biological systems.
It is part of a biopolymer in the bacterial cell wall, built from alternating units of GlcNAc and N-acetylmuramic acid (MurNAc), cross-linked with oligopeptides at the lactic acid residue of MurNAc. A cell wall is a tough flexible and sometimes fairly rigid layer surrounding a cell, located external to the Cell membrane, which provides the cell with structural N-Acetylmuramic acid, or MurNAc, is the Ether of Lactic acid and N-acetylglucosamine with a Chemical formula of C 11 An oligopeptide (oligo- "few" consists of between two and twelve amino acids Lactic acid ( IUPAC Systematic name: 2-hydroxypropanoic acid) also known as milk acid, is a Chemical compound that plays a role This layered structure is called peptidoglycan. Not to be confused with Glycoprotein. Peptidoglycan, also known as murein, is a Polymer consisting of sugars and amino
GlcNAc is the monomeric unit of the polymer chitin, which forms the outer coverings of insects and crustaceans. Chitin ( C 8 H 13 O 5 N)n (ˈkaɪtən is a long-chain Polymer of a N-acetylglucosamine Insects ( Class Insecta) are a major group of Arthropods and the most diverse group of Animals on the Earth with over a million described Structure of crustaceans As Arthropods crustaceans have a stiff Exoskeleton, which must be shed to allow the animal to grow ( Ecdysis or molting GlcNAc is also of note in neurotransmission, where it is thought to be an atypical neurotransmitter functioning in nocioceptive (pain) pathways. Neurotransmission (latin transmissio = passage crossing from transmitto = send let through also called synaptic transmission, is an electrical movement See Chemical synapse for an introduction to concepts and terminology used in this article Pain, in the sense of physical pain, is a typical sensory experience that may be described as the unpleasant awareness of a noxious stimulus or bodily harm
It has been proposed as a treatment for autoimmune diseases. Autoimmunity is the failure of an organism to recognize its own constituent parts as self, which results in an immune response against its own cells and tissues [1]