| Muir-Torre syndrome Classification and external resources |
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| eMedicine | derm/275 |
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Muir-Torre syndrome (MTS) is an inherited cancer syndrome that is thought to be a subtype of HNPCC. eMedicine is an online clinical medical knowledge base that was founded in 1996 by Scott Plantz and Richard Lavely two medical doctors In Medicine and Psychology, the term syndrome refers to the association of several clinically recognizable features signs (observed by a physician Cancer (medical term Malignant Neoplasm) is a class of Diseases in which a group of cells display uncontrolled Hereditary nonpolyposis colorectal cancer (HNPCC also known as Lynch syndrome, is characterised by a risk of Colorectal cancer and other cancers of the endometrium Individuals are prone to develop cancers of the colon, breast and genitourinary tract, and skin lesions, such as keratoacanthomas and sebaceous tumours. Keratoacanthoma (KA is a Benign or Pseudobenign, epithelial tumor that was previously considered to be a variant of Squamous cell carcinoma (SCC The genes affected are hMLH1 & hMSH2, and involved in DNA mismatch repair. DNA mismatch repair is a system for recognising and repairing erroneous insertion deletion and mis-incorporation of bases that can arise during DNA replication and recombination
External links
- Muir-Torre syndrome - Victoria Infirmary
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