Mastiff may refer to:

Dog breeds

• Molosser, a group of several breeds of dog also known as Mastiffs. Molosser is a type of large solidly-built Dogs comprising several breeds probably all descended from the same root stock
• American Mastiff, a breed of dog in the Molosser group. American Mastiff is a term that refers to a Molosser -type dog that is a cross between and English Mastiff and an Anatolian Mastiff dog
• Bullmastiff, said to be a cross between the English Mastiff and the Bulldog. The Bullmastiff is a powerful Dog, which was originally a cross between the English Mastiff and the Old English Bulldog. The English Mastiff, often called simply Mastiff, is a large breed of Dog of the general Mastiff or Molosser type The Bulldog, colloquially known as the British Bulldog or English Bulldog, is a medium-size breed of Dog that originated in England
• English Mastiff, a breed of dog in the Molosser group. The English Mastiff, often called simply Mastiff, is a large breed of Dog of the general Mastiff or Molosser type
• Spanish Mastiff, an ancient breed of dog originating in Spain. Spain () or the Kingdom of Spain (Reino de España is a country located mostly in southwestern Europe on the Iberian Peninsula.
• Neapolitan Mastiff, an ancient breed of dog originating in Italy. The Neapolitan Mastiff, Italian Mastiff, Mastino or Mastini is a large ancient Dog
• Tibetan Mastiff, an ancient breed of dog originating in Tibet.

Other

• Mastiff UAV - a battlefield UAV built by Tadiran Electronic Industries. An unmanned aerial vehicle (UAV is an unpiloted Aircraft. UAVs can be remote controlled or fly autonomously based on pre-programmed flight plans or more complex dynamic
• Mastiff Tech ( Software Product Development Company)
• Mastiff (company) - video game company. Mastiff is a company that publishes Video games, with offices located in both Tokyo and San Francisco.
• The British Army designation for the Cougar AFV

The British Army is the land armed forces branch of the British Armed Forces. The Cougar is an Armored fighting vehicle designed to be resistant to anti-vehicle mines and improvised munitions. An armoured fighting vehicle ( AFV) is a military Vehicle, protected by armour and armed with Weapons Most AFVs are equipped for driving in rugged

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