Historadiography is a technique formerly utilized in the fields of histology and cellular biology to provide semiquantitative information regarding the density of a tissue sample. Histology (from the Greek = 'tissue' is the study of the microscopic anatomy of cells and tissues of Plants and See also List of basic cell biology topics. Cell biology (also called cellular biology or formerly cytology, from the It is usually synonymous with microradiography. [1] This is achieved by layering a ground section of mineralized tissue (such as bone) with photographic emulsion on a glass slide and exposing the sample to a beam of X-rays. X-radiation (composed of X-rays) is a form of Electromagnetic radiation. After developing the emulsion, the resulting radiograph can be viewed with a microscope. A microscope ( Greek: ( micron) = small + ( skopein) = to look or see is an instrument for viewing objects that are A side-by-side comparison with a slide containing radiographs of various substances of known mass can provide a rough mass estimate, and therefore a rough approximation of the concentration of calcium salts in the sample.
Historadiography has also been used to visualize staining of tissue, such as spinal cord samples with thorotrast, which contains thorium that is opaque to X-rays. The spinal cord is a long thin tubular bundle of Nerves that is an extension of the Central nervous system from the brain and is enclosed in and protected Thorotrast is a suspension containing particles of the radioactive compound Thorium dioxide, ThO2 used as a Contrast medium in Thorium (ˈθɔːriəm is a Chemical element with the symbol Th and Atomic number 90 [2]
Over recent decades researchers have generally lost interest in historadiography. The most recent publication using the term (1998) to be indexed in PubMed[3] referred to autoradiography of tritium incorporated in thymidine. PubMed is a free search engine for accessing the MEDLINE database of citations and abstracts of biomedical research articles An autoradiograph is an image on an X-ray film or nuclear emulsion produced by the pattern of decay emissions (e Tritium (ˈtɹɪtiəm symbol or, also known as Hydrogen-3) is a radioactive Isotope of Hydrogen. Thymidine (more precisely called deoxythymidine; can also be labelled deoxyribosylthymine, and thymine deoxyriboside) is a Chemical compound [4]
References
- ^ CancerWeb Online Medical Dictionary.
- ^ F. P. BOHATIRCHUK , T. F. JELETZKY , and L. P. IVAN (1973). CONTACT HISTORADIOGRAPHY OF NERVOUS TISSUE IMPREGNATED WITH THOROTRAST.
- ^ PubMed search: historadiography.
- ^ PMID 9555564
Dictionary
historadiography
-noun
- the radiography of soft tissue using long wavelength X-rays of low penetrating power
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