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HMG-box transcription factor 1
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| PDB rendering based on 1v06. The Protein Data Bank ( PDB) is a repository for 3-D structural data of Proteins and Nucleic acids These data typically obtained by X-ray crystallography | ||
| Available structures: 1v06 | ||
| Identifiers | ||
| Symbol(s) | HBP1; FLJ16340 | |
| External IDs | MGI: 894659 HomoloGene: 8171 | |
| RNA expression pattern | ||
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| Orthologs | ||
| Human | Mouse | |
| Entrez | 26959 | 73389 |
| Ensembl | ENSG00000105856 | ENSMUSG00000002996 |
| Uniprot | O60381 | Q3UQS1 |
| Refseq | NM_012257 (mRNA) NP_036389 (protein) |
NM_153198 (mRNA) NP_694878 (protein) |
| Location | Chr 7: 106.6 - 106.63 Mb | Chr 12: 32.51 - 32.54 Mb |
| Pubmed search | [1] | [2] |
HMG-box transcription factor 1, also known as HBP1, is a human gene. The Human Genome Organisation (HUGO is an organization involved in the Human Genome Project, a project about mapping the human genome The Mouse Genome Informatics (MGI website is run by The Jackson Laboratory. HomoloGene, a tool of the National Center for Biotechnology Information (NCBI is a system for automated detection of homologs (similarity attributable to descent The Entrez Global Query Cross-Database Search System is a powerful Federated search engine or Web portal that allows users to search many discrete Health sciences Ensembl is a joint scientific project between the European Bioinformatics Institute and the Wellcome Trust Sanger Institute, which was launched in 1999 in response to the imminent UniProt is the uni versal prot ein resource a central repository of Protein data created by combining Swiss-Prot, TrEMBL PubMed is a free search engine for accessing the MEDLINE database of citations and abstracts of biomedical research articles History See also History of genetics The existence of genes was first suggested by Gregor Mendel (1822-1884 who in the 1860s studied inheritance [1]
References
Further reading
- Tevosian SG, Shih HH, Mendelson KG, et al. (1997). "HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family. ". Genes Dev. 11 (3): 383-96. PMID 9030690.
- Lavender P, Vandel L, Bannister AJ, Kouzarides T (1997). "The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A. ". Oncogene 14 (22): 2721-8. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 9178770.
- Zhuma T, Tyrrell R, Sekkali B, et al. (2000). "Human HMG box transcription factor HBP1: a role in hCD2 LCR function. ". EMBO J. 18 (22): 6396-406. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 10562551.
- Lemercier C, Duncliffe K, Boibessot I, et al. (2000). "Involvement of retinoblastoma protein and HBP1 in histone H1(0) gene expression. ". Mol. Cell. Biol. 20 (18): 6627-37. PMID 10958660.
- Shih HH, Xiu M, Berasi SP, et al. (2001). "HMG box transcriptional repressor HBP1 maintains a proliferation barrier in differentiated liver tissue. ". Mol. Cell. Biol. 21 (17): 5723-32. PMID 11486012.
- Sampson EM, Haque ZK, Ku MC, et al. (2001). "Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1. ". EMBO J. 20 (16): 4500-11. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 11500377.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ". Proc. Natl. Acad. Sci. U. S. A. 99 (26): 16899-903. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 12477932.
- Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7. ". Nature 424 (6945): 157-64. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 12853948.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs. ". Nat. Genet. 36 (1): 40-5. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 14702039.
- de Chiara C, Kelly G, Frenkiel TA, Pastore A (2004). "Assignment of the 1H, 13C, and 15N resonances of the AXH domain of the transcription factor HBP1. ". J. Biomol. NMR 28 (4): 411-2. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 14872137.
- Berasi SP, Xiu M, Yee AS, Paulson KE (2004). "HBP1 repression of the p47phox gene: cell cycle regulation via the NADPH oxidase. ". Mol. Cell. Biol. 24 (7): 3011-24. PMID 15024088.
- Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway. ". Genome Res. 14 (7): 1324-32. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 15231748.
- Swanson KA, Knoepfler PS, Huang K, et al. (2004). "HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations. ". Nat. Struct. Mol. Biol. 11 (8): 738-46. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 15235594.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ". Genome Res. 14 (10B): 2121-7. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 15489334.
- Yao CJ, Works K, Romagnoli PA, Austin GE (2005). "Effects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cells. ". Leukemia 19 (11): 1958-68. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 16179914.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network. ". Nature 437 (7062): 1173-8. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 16189514.
- Sekkali B, Szabat E, Ktistaki E, et al. (2005). "Human high mobility group box transcription factor 1 affects thymocyte development and transgene variegation. ". J. Immunol. 175 (8): 5203-12. PMID 16210625.
- Kim J, Zhang X, Rieger-Christ KM, et al. (2006). "Suppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1. ". J. Biol. Chem. 281 (16): 10865-75. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 16495219.
- Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. ". Cell 125 (4): 801-14. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 16713569.
- Zhang X, Kim J, Ruthazer R, et al. (2007). "The HBP1 transcriptional repressor participates in RAS-induced premature senescence. ". Mol. Cell. Biol. 26 (22): 8252-66. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 16966377.
External links
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