Genodermatosis ("geno", relating to genes; "dermatosis", skin disease; plural = genodermatoses) is a medical term for a hereditary skin disorder, caused by a genetic mutation or mutations in a gene or genes whose function(s) is/are important in maintaining the normal physiology of the skin[1]. The skin is the outer covering of living tissue of an animal (or plant In biology mutations are changes to the Nucleotide sequence of the Genetic material of an organism History See also History of genetics The existence of genes was first suggested by Gregor Mendel (1822-1884 who in the 1860s studied inheritance Physiology (from Greek grc φύσις physis, "nature origin" and grc -λογία -logia) is the study of the mechanical physical The skin is the outer covering of living tissue of an animal (or plant