|
GTP binding protein 1
|
||
| Identifiers | ||
| Symbol(s) | GTPBP1; GP-1; GP1; HSPC018; MGC20069 | |
| External IDs | OMIM: 602245 MGI: 109443 HomoloGene: 3165 | |
| RNA expression pattern | ||
|
|
||
| Orthologs | ||
| Human | Mouse | |
| Entrez | 9567 | 14904 |
| Ensembl | ENSG00000100226 | ENSMUSG00000042535 |
| Uniprot | O00178 | O08582 |
| Refseq | NM_004286 (mRNA) NP_004277 (protein) |
NM_013818 (mRNA) NP_038846 (protein) |
| Location | Chr 22: 37.43 - 37.46 Mb | Chr 15: 79.52 - 79.55 Mb |
| Pubmed search | [1] | [2] |
GTP binding protein 1, also known as GTPBP1, is a human gene. The Human Genome Organisation (HUGO is an organization involved in the Human Genome Project, a project about mapping the human genome The Mouse Genome Informatics (MGI website is run by The Jackson Laboratory. HomoloGene, a tool of the National Center for Biotechnology Information (NCBI is a system for automated detection of homologs (similarity attributable to descent The Entrez Global Query Cross-Database Search System is a powerful Federated search engine or Web portal that allows users to search many discrete Health sciences Ensembl is a joint scientific project between the European Bioinformatics Institute and the Wellcome Trust Sanger Institute, which was launched in 1999 in response to the imminent UniProt is the uni versal prot ein resource a central repository of Protein data created by combining Swiss-Prot, TrEMBL PubMed is a free search engine for accessing the MEDLINE database of citations and abstracts of biomedical research articles History See also History of genetics The existence of genes was first suggested by Gregor Mendel (1822-1884 who in the 1860s studied inheritance [1]
This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [1]
References
Further reading
- Senju S, Nishimura Y (1997). "Identification of human and mouse GP-1, a putative member of a novel G-protein family. ". Biochem. Biophys. Res. Commun. 231 (2): 360–4. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 9070279.
- Goretzki L, Mueller BM (1999). "Low-density-lipoprotein-receptor-related protein (LRP) interacts with a GTP-binding protein. ". Biochem. J. 336 ( Pt 2): 381–6. PMID 9820815.
- Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22. ". Nature 402 (6761): 489–95. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 10591208.
- Kudo H, Senju S, Mitsuya H, Nishimura Y (2000). "Mouse and human GTPBP2, newly identified members of the GP-1 family of GTPase. ". Biochem. Biophys. Res. Commun. 272 (2): 456–65. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 10833435.
- Senju S, Iyama K, Kudo H, et al. (2000). "Immunocytochemical analyses and targeted gene disruption of GTPBP1. ". Mol. Cell. Biol. 20 (17): 6195–200. PMID 10938096.
- Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. ". Genome Res. 10 (10): 1546–60. PMID 11042152.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ". Proc. Natl. Acad. Sci. U. S. A. 99 (26): 16899–903. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs. ". Nat. Genet. 36 (1): 40–5. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 14702039.
- Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome. ". Genome Biol. 5 (10): R84. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 15461802.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ". Genome Res. 14 (10B): 2121–7. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 15489334.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. ". Cell 127 (3): 635–48. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 17081983.
Dapyx Software network: MP3 Explorer | Ebook Manager | Zenithic