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Gamma-hydroxybutyrate receptor or GHB receptor is a receptor that binds gamma-Hydroxybutyric acid. gamma -Hydroxybutyric acid, 4-hydroxybutanoic acid, GHB, or fantasy is a naturally-occurring substance found in the Central nervous Its existence was predicted by observing the action of its agonists that previously were thought to act on GABA-B receptors. [1] The rat GHB receptor was first cloned and characterised in 2003[2] followed by the human receptor in 2007. Year 2003 ( MMIII) was a Common year starting on Wednesday of the Gregorian calendar. [3] It is a G-protein coupled receptor. G protein-coupled receptors ( GPCRs) also known as seven transmembrane domain receptors, 7TM receptors, heptahelical receptors, and

See also

References

  1. ^ Snead OC (November 2000). gamma -Hydroxybutyric acid, 4-hydroxybutanoic acid, GHB, or fantasy is a naturally-occurring substance found in the Central nervous "Evidence for a G protein-coupled gamma-hydroxybutyric acid receptor". J. Neurochem. 75 (5): 1986–96. PMID 11032888.  
  2. ^ Andriamampandry C, Taleb O, Viry S, et al (September 2003). "Cloning and characterization of a rat brain receptor that binds the endogenous neuromodulator gamma-hydroxybutyrate (GHB)". FASEB J. 17 (12): 1691–3. doi:10.1096/fj.02-0846fje. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 12958178.  
  3. ^ Andriamampandry C, Taleb O, Kemmel V, Humbert JP, Aunis D, Maitre M (March 2007). "Cloning and functional characterization of a gamma-hydroxybutyrate receptor identified in the human brain". FASEB J. 21 (3): 885–95. doi:10.1096/fj.06-6509com. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 17197387.  
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