Fructose 6-phosphate
IUPAC name	[(2R,3R,4S)-3,4,5-trihydroxy-5- (hydroxymethyl)oxolan-2-yl] methoxyphosphonic acid
Other names	β-D-fructose 6-phosphate, fructose 6-phosphate
Abbreviations	F6P
Molecular formula	C6H13O9P
Molar mass	262. IUPAC Nomenclature is a system of naming Chemical compounds and of describing the science of Chemistry in general A chemical formula is a way of expressing information about the Atoms that constitute a particular Chemical compound, and how the relationship between those atoms changes Molar mass, symbol M, is the Mass of one mole of a substance ( Chemical element or Chemical compound) 1535 g/mol
CAS number	[643-13-0]
SMILES	O1C(CO)(O)C(O)C(O)C1COP (O)(O)=O
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Fructose 6-phosphate (also known as the Neuberg ester) is fructose sugar phosphorylated on carbon 6 (ie. CAS registry numbers are unique numerical identifiers for Chemical compounds Polymers biological sequences mixtures and Alloys They are also referred to In Chemistry, the standard state of a material is its state at 1 bar (100 Kilopascals exactly Fructose (also levulose or laevulose) is a simple reducing Sugar ( Monosaccharide) found in many foods and is one of the three Phosphorylation is the addition of a Phosphate (PO4 group to a Protein molecule or a small molecule is a fructosephosphate). Fructosephosphates are Sugar phosphates based upon Fructose, and are common in the Biochemistry of cells Fructosephosphates play integral The β-D-form of this compound is very common in cells. The cell is the structural and functional unit of all known living Organisms It is the smallest unit of an organism that is classified as living and is often called The vast majority of glucose and fructose entering a cell will become converted to this at some point. Glucose (Glc a Monosaccharide (or simple Sugar) also known as grape sugar, is an important Carbohydrate in Biology. The name Neuberg ester comes from the German biochemist Carl Neuberg. Carl Alexander Neuberg (1877-1956 was an early pioneer in Biochemistry, and often referred to as the "Father of Biochemistry"

Contents 1 History 2 Fructose 6-phosphate in glycolysis 3 Fructose 6-phosphate isomerism 4 See also 5 References

History

In 1918, Carl Neuberg found that the compound (only later identified as fructose 6-phosphate) could be produced by mild acid hydrolysis of "Harden-Young ester" (fructose 2,6-bisphosphate). Carl Alexander Neuberg (1877-1956 was an early pioneer in Biochemistry, and often referred to as the "Father of Biochemistry" Fructose 26-bisphosphate (or fructose 26-diphosphate) abbreviated Fru-26- P 2 is a metabolite which Allosterically affects the activity of ^[1]

Fructose 6-phosphate in glycolysis

Fructose 6-phosphate lies within the glycolysis metabolic pathway and is produced by isomerisation of glucose 6-phosphate. See also Gluconeogenesis, which carries out a process wherein glucose is synthesized rather than catabolized In Biochemistry, a metabolic pathway is a series of chemical reactions occurring within a cell. Glucose 6-phosphate (also known as Robison ester) is Glucose sugar Phosphorylated on carbon 6 It is in turn further phosphorylated to fructose-1,6-bisphosphate. Fructose 16-phosphate is Fructose sugar Phosphorylated on carbons 1 and 6 (ie

α-D-glucose 6-phosphate	Phosphoglucose isomerase		β-D-fructose 6-phosphate	Phosphofructokinase-1		β-D-fructose 1,6-bisphosphate
				ATP	ADP
				Pi	H2O
	Phosphoglucose isomerase			Fructose bisphosphatase

Compound C00668 at KEGG Pathway Database. Glucose 6-phosphate (also known as Robison ester) is Glucose sugar Phosphorylated on carbon 6 Glucose-6-phosphate isomerase, or phosphoglucose isomerase, is an Enzyme ( that catalyzes the conversion of Glucose-6-phosphate into Fructose-6-phosphate Phosphofructokinase-1 (PFK-1 is the most important regulatory Enzyme ( of Glycolysis. Fructose 16-phosphate is Fructose sugar Phosphorylated on carbons 1 and 6 (ie Adenosine-5'-triphosphate ( ATP) is a multifunctional Nucleotide that is most important as a " molecular currency" of intracellular Energy Glucose-6-phosphate isomerase, or phosphoglucose isomerase, is an Enzyme ( that catalyzes the conversion of Glucose-6-phosphate into Fructose-6-phosphate KEGG ( Kyoto Encyclopedia of Genes and Genomes) is a collection of Online databases dealing with Genomes Enzymatic pathways and biological chemicals Enzyme 5.3.1.9 at KEGG Pathway Database. KEGG ( Kyoto Encyclopedia of Genes and Genomes) is a collection of Online databases dealing with Genomes Enzymatic pathways and biological chemicals Compound C05345 at KEGG Pathway Database. KEGG ( Kyoto Encyclopedia of Genes and Genomes) is a collection of Online databases dealing with Genomes Enzymatic pathways and biological chemicals Enzyme 2.7.1.11 at KEGG Pathway Database. KEGG ( Kyoto Encyclopedia of Genes and Genomes) is a collection of Online databases dealing with Genomes Enzymatic pathways and biological chemicals Enzyme 3.1.3.11 at KEGG Pathway Database. KEGG ( Kyoto Encyclopedia of Genes and Genomes) is a collection of Online databases dealing with Genomes Enzymatic pathways and biological chemicals Reaction [1] at KEGG Pathway Database. KEGG ( Kyoto Encyclopedia of Genes and Genomes) is a collection of Online databases dealing with Genomes Enzymatic pathways and biological chemicals Compound C05378 at KEGG Pathway Database. KEGG ( Kyoto Encyclopedia of Genes and Genomes) is a collection of Online databases dealing with Genomes Enzymatic pathways and biological chemicals

Fructose 6-phosphate isomerism

Main article: Fructose

Fructose 6-phosphate has only one biologically active isomer, the β-D-form. Fructose (also levulose or laevulose) is a simple reducing Sugar ( Monosaccharide) found in many foods and is one of the three This article is about the chemical concept For "isomerism" of atomic nuclei see Nuclear isomer. There are many other isomers, analogous to those of fructose.

See also

• Phosphofructokinase 2 is Fructose 2,6-bisphosphatase. Phosphofructokinase-2 ( PFK2) is one activity of a bifunctional Enzyme ( the other of which is Fructose 26-bisphosphatase (FBPase2 Fructose-26-bisphosphatase is an Enzyme that catalyzes the following reaction Fructose-26-bisphosphate + H2O ---> Fructose-6-phosphate + This is one of the regulatory reactions of glycolysis.
• Mannose phosphate isomerase creates mannose-6-phosphate. Mannose phosphate isomerase is an Enzyme which converts Fructose-6-phosphate and Mannose-6-phosphate. Mannose-6-phosphate (M6P is a molecule bound by Lectin in the Immune system.

References

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