Citizendia
Your Ad Here

Friedrich Miescher
Friedrich Miescher
Friedrich Miescher
Born 13 August 1844
Basel
Died 26 August 1895
Davos
Nationality Swiss
Fields biology
Known for nucleic acids

Johan Friedrich Miescher (13 August 1844, Basel - 26 August 1895, Davos) was a Swiss biologist. Events 3114 BC - According to the Lounsbury correlation the start of the Maya calendar. Year 1844 ( MDCCCXLIV) was a Leap year starting on Monday (link will display the full calendar of the Gregorian Calendar (or a Leap year "Basilia" redirects here For the Fly Genus, see Basilia (fly. Events 1071 - Battle of Manzikert: The Seljuk Turks defeat the Byzantine Army at Manzikert. Year 1895 ( MDCCCXCV) was a Common year starting on Tuesday (link will display full calendar of the Gregorian calendar (or a Common year Davos ( Romansh: Tavau, Italian: Tavate is a municipality in the district of Prättigau/Davos in the canton of Switzerland (English pronunciation; Schweiz Swiss German: Schwyz or Schwiiz Suisse Svizzera Svizra officially the Swiss Confederation Foundations of modern biology There are five unifying principles A nucleic acid is a Macromolecule composed of chains of monomeric Nucleotides In Biochemistry these Molecules carry Genetic information Events 3114 BC - According to the Lounsbury correlation the start of the Maya calendar. Year 1844 ( MDCCCXLIV) was a Leap year starting on Monday (link will display the full calendar of the Gregorian Calendar (or a Leap year "Basilia" redirects here For the Fly Genus, see Basilia (fly. Events 1071 - Battle of Manzikert: The Seljuk Turks defeat the Byzantine Army at Manzikert. Year 1895 ( MDCCCXCV) was a Common year starting on Tuesday (link will display full calendar of the Gregorian calendar (or a Common year Davos ( Romansh: Tavau, Italian: Tavate is a municipality in the district of Prättigau/Davos in the canton of Switzerland (English pronunciation; Schweiz Swiss German: Schwyz or Schwiiz Suisse Svizzera Svizra officially the Swiss Confederation A biologist is a Scientist devoted to and producing results in Biology through the study of Organisms Typically biologists study organisms and their relationship He isolated various phosphate-rich chemicals, which he called nuclein (now nucleic acids), from the nuclei of white blood cells in 1869 at Felix Hoppe-Seyler's laboratory at the University of Tübingen, Germany, paving the way for the identification of DNA as the carrier of inheritance. A nucleic acid is a Macromolecule composed of chains of monomeric Nucleotides In Biochemistry these Molecules carry Genetic information Year 1869 ( MDCCCLXIX) is a Common year starting on Friday (link will display the full calendar of the Gregorian calendar (or a Common year Ernst Felix Immanuel Hoppe-Seyler (December 26 1825 &ndash August 10 1895 was a German Physiologist and Chemist. Eberhard Karls University of Tübingen ( German: Eberhard Karls Universität Tübingen, sometimes called the "Eberhardina Carolina" is a public university Germany, officially the Federal Republic of Germany ( ˈbʊndəsʁepuˌbliːk ˈdɔʏtʃlant is a Country in Central Europe. Deoxyribonucleic acid ( DNA) is a Nucleic acid that contains the genetic instructions used in the development and functioning of all known The significance of the discovery, first published in 1871, was not at first apparent, and it was Albrecht Kossel who made the initial inquiries into its chemical structure. Year 1871 ( MDCCCLXXI) was a Common year starting on Sunday (link will display the full calendar of the Gregorian calendar (or a Common Ludwig Karl Martin Leonhard Albrecht Kossel ( September 16, 1853 &ndash July 5, 1927) was a German medical doctor

Miescher came from a scientific family: his father and his uncle held the chair of anatomy at the University of Basel. The University of Basel (German Universität Basel) is located at Basel, Switzerland. As a boy he was shy but intelligent. He had a partial hearing impairment due to a severe attack of typhus. Typhus is any of several similar diseases caused by Louse -borne bacteria But this did not stop him from having an interest in music and his father performed publicly. Miescher himself studied medicine at Basel. In the summer of 1865 Friedrich worked for the organic chemist Adolf Stecker in Göttingen. The University of Göttingen ( German: Georg-August-Universität Göttingen) is a University in the city of Göttingen, Germany. His studies were interrupted for the year when he became ill with typhoid fever; however, he still received his M. D. in 1868.

Miescher felt that his partial deafness would be a disadvantage as a doctor so he turned to physiological chemistry. Miescher originally wanted to study lymphocytes but was encouraged by Felix Hoppe-Seyler to study leucocytes. A lymphocyte is a type of White blood cell in the Vertebrate Immune system. Ernst Felix Immanuel Hoppe-Seyler (December 26 1825 &ndash August 10 1895 was a German Physiologist and Chemist. Miescher was interested in studying the chemistry of the nucleus. The nucleus of an Atom is the very dense region consisting of Nucleons ( Protons and Neutrons, at the center of an atom Lymphocytes were difficult to obtain in sufficient enough numbers to study while leucocytes were known to be the one of the main components in pus and could be obtained from bandages at the nearby hospital. The problem was, however, washing the cells off the bandages without damaging them.

Miescher devised different salt solutions eventually producing one with sodium sulfate. The cells were filtered. Since centrifuges were not present at this time the cells were allowed to settle at the bottom of a beaker. He then tried to isolate the nuclei free of cytoplasm. He subjected the purified nuclei to an alkaline extraction followed by acidification resulting in a precipitate being formed which Miescher called nuclein (now known as DNA). Deoxyribonucleic acid ( DNA) is a Nucleic acid that contains the genetic instructions used in the development and functioning of all known He found that this contained phosphorus, nitrogen, and sulfur. The discovery was so unlike anything else at the time that Hoppe-Seyler repeated all Miescher's research himself before publishing it in his journal. Ernst Felix Immanuel Hoppe-Seyler (December 26 1825 &ndash August 10 1895 was a German Physiologist and Chemist. Friedrich then went on to study physiology at Leipzig in the laboratory of Carl Ludwig for a year before returning to Basel where he was appointed professor of physiology.

Miescher and his students researched much of the nucleic acid chemistry but their function remained unknown. However, his discovery played an important part in the identification of nucleic acids as the carriers of inheritance. The importance of Miescher's discovery was not apparent until Albrecht Kossel (a German physiologist specializing in the physiological chemistry of the cell and its nucleus and of proteins) carried out research on the chemical structure of nuclein. Friedrich Miescher is also known for demonstrating that carbon dioxide concentrations in blood regulate breathing.

He died of tuberculosis in 1895 aged 51. Tuberculosis (abbreviated as TB for tubercle bacillus or T u' b' erculosis Bacillus --> is a common He has had a laboratory of the Max Planck Society in Tübingen and a research institute in Basel named after him. Tübingen, a traditional University town in Baden-Württemberg, Germany, is situated 30 km (19 miles southwest of Stuttgart, on a ridge between "Basilia" redirects here For the Fly Genus, see Basilia (fly.


References

External Links

The Max Planck Institute for the History of Science in Berlin was established in March 1994
© 2009 citizendia.org; parts available under the terms of GNU Free Documentation License, from http://en.wikipedia.org
 Dapyx Software network: MP3 Explorer | Ebook Manager | Zenithic