Francisco Rodriguez may refer to:
- Francisco Rodriguez (baseball), relief pitcher for the Los Angeles Angels of Anaheim
- Francisco Rodríguez (boxer)
- Francisco Rodriguez (poet), El Salvador
- Francisco Rodríguez (President of Panama)
- Francisco Rodriguez (actor)
- Francisco Javier Rodríguez, a Mexican footballer. Francisco "Frankie" José Rodriguez (born January 7 1982 in Caracas, Venezuela) is a Major League Baseball player Francisco Antonio Rodríguez Brito (born September 20, 1945 in Cumaná, Sucre) is a former Venezuelan boxer. El Salvador ( República de El Salvador,) is a country in Central America. Francisco Antonio Rodríguez Poveda (born November 24, 1938 in Herrera Province) was provisional President of Panama from September 1 Francisco Javier "Maza" Rodríguez Pinedo (born October 20, 1981 in Mazatlan, Sinaloa) is a Mexican football
- Francisco Rodríguez García, a Spanish footballer. Francésc Rodríguez García (born 8 March 1934 in Barcelona) nicknamed Rodri, is a former Spanish footballer
- Francisco Rodríguez (Colombian footballer), a Colombian footballer.
- Francisco Rodríguez S. J. (Archbishop of the Archdiocese of Angamalé)
- Francisco Rodríguez Quiroga(Geólogo-Geofísico)
- Francisco Rodriguez (Geólogo), Colombiano
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