In enzymology, a formyl-CoA hydrolase (EC 3.1.2.10) is an enzyme that catalyzes the chemical reaction

formyl-CoA + H₂O CoA + formate

Thus, the two substrates of this enzyme are formyl-CoA and H₂O, whereas its two products are CoA and formate. Enzymes are Biomolecules that catalyze ( ie increase the rates of Chemical reactions Almost all enzymes are Proteins This article is about the Enzyme Commission codes For the European Commission system for coding chemicals see EC-No. Enzymes are Biomolecules that catalyze ( ie increase the rates of Chemical reactions Almost all enzymes are Proteins Catalysis is the process in which the rate of a Chemical reaction is increased by means of a Chemical substance known as a catalyst A chemical reaction is a process that always results in the interconversion of Chemical substances The substance or substances initially involved in a chemical reaction are called Water is a common Chemical substance that is essential for the survival of all known forms of Life. A product is a substance that forms as a result of a Biological - or Chemical reaction. Coenzyme A ( CoA, CoASH, or HSCoA) is a Coenzyme, notable for its role in the synthesis and oxidation of Fatty acids Formate or methanoate is the ion CHOO&minus ( Formic acid minus one Hydrogen ion)

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. In Biochemistry, a hydrolase is an Enzyme that catalyzes the Hydrolysis of a Chemical bond. Thioesters are compounds resulting from the bonding of Sulfur with an Acyl group with the general formula R-S-CO-R'. The systematic name of this enzyme class is formyl-CoA hydrolase. This enzyme is also called formyl coenzyme A hydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

• IUBMB entry for 3.1.2.10
• BRENDA references for 3.1.2.10 (Recommended. )
• PubMed references for 3.1.2.10
• PubMed Central references for 3.1.2.10
• Google Scholar references for 3.1.2.10
• Sly WS and Stadtman ER (1963). "Formate metabolism. I. Formyl coenzyme A, an intermediate in the formate-dependent decomposition of acetyl phosphate in Clostridium kluyveri". J. Biol. Chem. 238: 2632–2638.  

External links

The CAS registry number for this enzyme class is 9025-91-6. CAS registry numbers are unique numerical identifiers for Chemical compounds Polymers biological sequences mixtures and Alloys They are also referred to

• IUBMB entry for 3.1.2.10

• KEGG entry for 3.1.2.10

• BRENDA entry for 3.1.2.10

• NiceZyme view of 3.1.2.10

• EC2PDB: PDB structures for 3.1.2.10

• PRIAM entry for 3.1.2.10

• PUMA2 entry for 3.1.2.10

• IntEnz: Integrated Enzyme entry for 3.1.2.10

• MetaCyc entry for 3.1.2.10

• Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

• EGO entry for GO code 0047901: formyl-CoA hydrolase

• AMIGO entry for GO code 0047901: formyl-CoA hydrolase

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