| ICD-10 | R25.3 |
|---|---|
| ICD-9 | 781.0 |
| DiseasesDB | 18832 |
| MedlinePlus | 003296 |
| MeSH | D005207 |
A fasciculation (or "muscle twitch") is a small, local, involuntary muscle contraction (twitching) visible under the skin arising from the spontaneous discharge of a bundle of skeletal muscle fibers. A symptom' (from Greek σύμπτωμα, "accident misfortune that which befalls" from συμπίπτω, "I befall" from A Sign is an indication of some fact or quality and a medical sign is an objective indication of some medical fact or quality that is detected by a Physician The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify Diseases The International Statistical Classification of Diseases and Related Health Problems 10th Revision ( ICD -10) is a coding of diseases and signs symptoms abnormal findings R00-R69 - Symptoms and Signs (R00-R09 Circulatory and Respiratory systems ( Abnormalities of Heart beat The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify Diseases The following is a list of codes for International Statistical Classification of Diseases and Related Health Problems. The Diseases Database is a free Website that provides information about the relationships between medical conditions Symptoms, and Medications. MedlinePlus, with the MedlinePlus Medical Encyclopedia, is a website network containing Health information from the world's largest medical Library Medical Subject Headings ( MeSH) is a huge Controlled vocabulary (or metadata system for the purpose of indexing journal articles and books A muscles contraction (also known as a muscle twitch or simply twitch) occurs when a Muscle fibre generates tension through the action of Actin Skeletal muscle is a type of Striated muscle, which usually attaches to tendons Fasciculations have a variety of causes, the majority of which are benign, but can also be due to disease of the motor neurons.
Contents |
Causes and risk factors
Conditions
- The origin of most cases is at present unknown and has therefore been given the title benign fasciculation syndrome[1]. Benign fasciculation syndrome ( BFS) is a Neurological disorder characterized by Fasciculation (twitching of various voluntary muscles in
- Lower motor neuron lesions
- Werdnig-Hoffman disease
- Amyotrophic lateral sclerosis (rare)
- Kennedy disease
- Organophosphate poisoning
- Benzodiazepine withdrawal
- Magnesium deficiency (which can be caused by stress)
- Multiple Sclerosis
- Dehydration
- Fatigue
- Lyme Disease
Medications
Other risk factors may include the use of anticholinergic drugs over long periods, in particular ethanolamines such as Benadryl, as well as lorazepam, used as an antihistamine anxiety, and sleep aid, and Dramamine for nausea and motion sickness. A lower motor neuron lesion is a lesion which affects nerve fibers travelling from the anterior horn of the Spinal cord to the relevant Muscle (s -- the Werdnig-Hoffman disease (also known as "Severe infantile spinal muscular atrophy" or "spinal muscular atrophy type I" is an Autosomal recessive Amyotrophic Lateral Sclerosis ( ALS, sometimes called Maladie de Charcot, or in the United States Lou Gehrig's Disease) is a progressive Kennedy's disease (KD or X-linked spinal and bulbar muscular atrophy (SBMA is a neuromuscular disease associated with mutation of the Androgen receptor (AR Many Organophosphates are potent Neurotoxins functioning by inhibiting the action of Acetylcholinesterase (AChE in nerve cells. Benzodiazepine withdrawal syndrome is caused by stopping benzodiazepines or during dosage reduction of Benzodiazepines. Magnesium deficiency refers to an absolute lack of Magnesium, the result of numerous conditions Dehydration ( hypohydration) is the removal of Water ( hydro in ancient Greek) from an object Lyme disease, or borreliosis, is an Emerging infectious disease caused by at least three Species of Bacteria belonging to the Genus An anticholinergic agent is a substance that blocks the Neurotransmitter acetylcholine in the central and the Peripheral nervous system. Ethanolamine, also called 2-aminoethanol or monoethanolamine (often abbreviated as ETA or MEA) is an Organic chemical compound Pharmacological action Diphenhydramine (dye fen hye' dra meen works by blocking the effect of histamine at H1 receptor sites Lorazepam (also known by its brand name Ativan or Temesta) is a Benzodiazepine drug with short to medium duration of action Dimenhydrinate (marketed under brand names Dramamine, Gravol and Vertirosan) is an Over-the-counter drug used to prevent Nausea Persons with Benign fasciculation syndrome (BFS) may experience paraesthesia shortly after taking such medication; hours later as it wears off (especially upon awaking), fasciculation episodes begin. Benign fasciculation syndrome ( BFS) is a Neurological disorder characterized by Fasciculation (twitching of various voluntary muscles in Paresthesia (pron /ˌpɛɹɪsˈθiʒə/ paraesthesia in British English, pron
Stimulants can cause fasciculations directly. Stimulant drugs are Drugs that temporarily increase alertness and awareness These include caffeine, pseudoephedrine (Sudafed), and the asthma bronchodilators albuterol/salbutamol (e. Caffeine is a bitter white crystalline Xanthine Alkaloid that acts as a Psychoactive Stimulant Drug and a mild Diuretic Pseudoephedrine (commonly abbreviated as PSE is a sympathomimetic Amine commonly used as a Decongestant. Asthma is a chronic Condition involving the Respiratory system in which the airways occasionally constrict become inflamed, and are A bronchodilator is a substance that dilates the bronchi and Bronchioles decreasing airway resistance and thereby facilitating airflow Salbutamol ( INN) or albuterol ( USAN) is a short-acting β2-adrenergic receptor agonist used for the relief of Bronchospasm g. Proventil, Combivent, Ventolin). Medications used to treat attention deficit disorder often contain stimulants as well, and are common causes of benign fasciculations. Attention-Deficit Hyperactivity Disorder (ADHD is a neurobehavioral developmental disorder affecting about 3-5% of the world's population
Treatment
Inadequate magnesium intake can cause fasciculations, especially after a magnesium loss due to severe diarrhea. Magnesium (mægˈniːziəm is a Chemical element with the symbol Mg, Atomic number 12 Atomic weight 24 In Medicine, diarrhea, also spelled diarrhoea (see spelling differences) is frequent loose or liquid Bowel movements Acute diarrhea Over-exertion is another risk factor for magnesium loss. As much as 80% of the population does not get the recommended daily amount of magnesium; this may be a common cause. Treatment is with supplements or increased intake of foods rich in magnesium, especially almonds & other nuts, and bananas. Ironically, magnesium supplements may result in diarrhea and more magnesium loss, so dosage and timing (i. e. with meals) are important.
Fasciculation also often occurs during a rest period after sustained stress, such as that brought on by unconsciously tense muscles. Reducing stress and anxiety is therefore another useful treatment.
Atropine Sulfate can be used with Suxamethonium chloride to decrease fasciculations during RSI (rapid sequence intubation)
References
- ^ Blexrud MD, Windebank AJ, Daube JR (1993). "Long-term follow-up of 121 patients with benign fasciculations". Ann. Neurol. 34 (4): 622-5. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 8215252.
External links
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