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Esophageal web
Classification and external resources
ICD-10 Q39.4
DiseasesDB 31503
eMedicine med/3413 

Esophageal webs are thin membranes located in the middle or upper esophagus. The International Statistical Classification of Diseases and Related Health Problems (most commonly known by the abbreviation ICD) provides codes to classify Diseases The International Statistical Classification of Diseases and Related Health Problems 10th Revision ( ICD -10) is a coding of diseases and signs symptoms abnormal findings Q00-Q89 - Congenital malformations and deformations (Q00-Q07 Nervous system ( Anencephaly and similar malformations The Diseases Database is a free Website that provides information about the relationships between medical conditions Symptoms, and Medications. eMedicine is an online clinical medical knowledge base that was founded in 1996 by Scott Plantz and Richard Lavely two medical doctors The esophagus or oesophagus (see American and British English spelling differences) sometimes known as the gullet, is an organ in

Presentation

Its main symptoms are pain and difficulty in swallowing (odynophagia). Pain, in the sense of physical pain, is a typical sensory experience that may be described as the unpleasant awareness of a noxious stimulus or bodily harm Swallowing, known scientifically as deglutition is the process in the human or animal body that makes something pass from the Mouth, to the Pharynx, into Odynophagia is Painful Swallowing, in the mouth ( Oropharynx) or Esophagus.

Esophageal webs are thin (2-3mm) membranes of normal esophageal tissue consisting of mucosa and submucosa. They can be congenital or acquired. Congenital webs commonly appear in the middle and inferior third of the esophagus, and they are more likely to be circumferential with a central or eccentric orifice. Acquired webs are much more common than congenital webs and typically appear in the cervical area (postcricoid).

Clinical symptoms of this condition are selective (solid more than liquids) dysphagia, thoracic pain, nasopharyngeal reflux, aspiration, perforation and food impaction (the last two are very rare). Dysphagia should not be confused with the similarly pronounced Dysphasia, a language disorder

Causes and associated conditions

They are mainly observed in the Plummer-Vinson syndrome, which is associated with chronic iron deficiency anemia. Plummer-Vinson syndrome ( PVS) also called Paterson-Brown-Kelly syndrome or sideropenic dysphagia is a disorder linked to severe long-term Iron For a discussion of iron deficiency more broadly see the Wikipedia article iron deficiency.

Esophageal webs are associated with bullous diseases (such as epidermolysis bullosa, pemphigus, and bullous pemphigoid), with graft versus host disease involving the esophagus, and with celiac disease. Epidermolysis Bullosa ( EB) is a rare Genetic disease characterized by the presence of extremely fragile Skin and recurrent Blister Pemphigus (from the Greek pemphix: bubble or blister is an Autoimmune disease of the Skin and mucous membranes that causes vesicles Bullous pemphigoid, also referred to as BP, is a chronic autoimmune Skin disease, involving the formation of Blisters below the surface of the Graft-versus-host disease (GVHD is a common complication of allogeneic bone marrow transplantation in which functional immune cells in the transplanted marrow recognize Coeliac

Esophageal webs are more common in white individuals and in women (with a ratio 2:1). The literature describes relations between these webs and Plummer-Vinson Syndrome, bullous dermatologic disorders, inlet patch, graft-versus-host disease and celiac disease. The postulated mechanisms are sideropenic anemia (mechanism unknown) or some interference of the immune system. Esophageal webs can be ruptured during upper endoscopy.


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