Eosinophilic means loves eosin, and refers to the staining of certain tissues, cells, or organelles after they been washed with eosin, a dye. Eosin is a Fluorescent red Dye resulting from the action of Bromine on Fluorescein. A stain is a discoloration that can be clearly distinguished from the sufrace Tissue is a cellular organizational level intermediate between cells and a complete organism The cell is the structural and functional unit of all known living Organisms It is the smallest unit of an organism that is classified as living and is often called In Cell biology, an organelle (pronunciation /ɔː(rgəˡnɛl/ is a specialized subunit within a cell that has a specific function and is usually separately enclosed Eosin is a Fluorescent red Dye resulting from the action of Bromine on Fluorescein. A dye can generally be described as a Colored substance that has an affinity to the substrate to which it is being applied
Eosin is an acidic dye; thus, the structure being stained is basic. In Computer science, ACID ( Atomicity Consistency Isolation Durability) is a set of properties that guarantee that Database transactions are In Chemistry, a base is most commonly thought of as an aqueous substance that can accept Protons This refers to the Brønsted-Lowry theory of acids and
Eosinophilic describes the appearance of cells and structures seen in histological sections that take up the staining dye eosin. Histological section refers to thin slices of tissue applied to a Microscopic slide, usually around 5 to 10 Micrometres thick which are viewed Eosin is a Fluorescent red Dye resulting from the action of Bromine on Fluorescein. This is a bright-pink dye that stains the cytoplasm of cells, as well as extracellular proteins such as collagen. Collagen is the main Protein of Connective tissue in Animals and the most abundant protein in Mammals making up about 50% of the whole-body protein
Such eosinophilic structures are, in general, composed of protein. Proteins are large Organic compounds made of Amino acids arranged in a linear chain and joined together by Peptide bonds between the Carboxyl
The stain eosin is usually combined with a stain called hematoxylin to produce a hematoxylin and eosin-stained section (also called an H&E, HE or H+E section). Haematoxylin, hematoxylin, Natural Black 1, or CI 75290 is extracted from the wood of the Logwood tree This is the most widely-used histological stain in medical diagnosis, for example, when a pathologist examines a biopsy of a suspected cancer, the biopsy will have been stained with H&E. Pathology (from Greek grc πάθος pathos, "fate harm" and grc -λογία -logia) is the study and A biopsy (in Greek: βίος life and όψη look/appearance is a Medical test involving the removal of cells or tissues
Some structures seen inside cells are described as being eosinophilic, for example, Lewy bodies, Mallory bodies. Lewy bodies are abnormal aggregates of Protein that develop inside Nerve cells They are identified under the Microscope when Histology is performed Mallory bodies (also known as " Alcoholic Hyaline " or "Mallory's hyaline" are pathologic inclusions found in the Cytoplasm
See also
- basophilic (affinity to hematoxylln)
- Eosinophilia
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