Citizendia

Major endocrine glands. (Male left, female on the right.) 1. Pineal gland 2. Pituitary gland 3. Thyroid gland 4. Thymus 5. Adrenal gland 6. Pancreas 7. Ovary 8. Testes
Major endocrine glands. (Male left, female on the right. Male (♂ refers to the sex of an organism or part of an organism which produces small mobile Gametes called spermatozoa. Female (♀ is the Sex of an Organism, or a part of an organism which produces ova (egg cells ) 1. Pineal gland 2. The pineal gland (also called the pineal body, epiphysis cerebri, or epiphysis) is a small endocrine gland in the vertebrate Brain Pituitary gland 3. The pituitary gland, or hypophysis, is an Endocrine gland about the size of a Pea. Thyroid gland 4. The thyroid is one of the largest Endocrine glands in the body Thymus 5. In Human anatomy, the thymus is an organ located in the upper Anterior portion of the chest cavity just behind the Sternum. Adrenal gland 6. In Mammals the adrenal glands (also known as suprarenal glands) are the triangle-shaped Endocrine glands that sit on top of the Kidneys their Pancreas 7. The pancreas is a Gland organ in the digestive and Endocrine system of Vertebrates. Ovary 8. "Ovaria" redirects here This is also a proposed section and a Synonym of Solanum. Testes

The endocrine system is an integrated system of small organs that involve the release of extracellular signaling molecules known as hormones. The testicle (from Latin testiculus, diminutive of testis, meaning "witness" virility plural testes) is the male Hormones (from Greek ὁρμή - "impetus" are chemicals released by cells that affect cells in other parts of the body The endocrine system is instrumental in regulating metabolism, growth, development and puberty, tissue function, and also plays a part in determining mood. Metabolism is the set of Chemical reactions that occur in living Organisms in order to maintain Life. Human development is the process of Growing to maturity In biological terms this entails growth from a one-celled Zygote to an adult Human being Tissue is a cellular organizational level intermediate between cells and a complete organism [1] The field of medicine that deals with disorders of endocrine glands is endocrinology, a branch of the wider field of internal medicine. Medicine is the art and science of healing It encompasses a range of Health care practices evolved to maintain and restore Human Health by the Endocrinology (from Greek grc ἔνδον endon, "within" grc κρῑνω krīnō, "to separate" and grc -λογία Internal medicine is the medical specialty concerned with the diagnosis management and nonsurgical treatment of unusual or serious diseases

Contents

Function

The Endocrine system is an information signal system much like the nervous system. The nervous system is a Network of specialized cells that communicate information about an animal's surroundings and itself However, the nervous system uses nerves to conduct information, whereas the endocrine system mainly uses blood vessels as information channels. The blood vessels are part of the Circulatory system and function to transport Blood throughout the body Glands located in many regions of the body release into the bloodstream specific chemical messengers called hormones. Hormones regulate the many and varied functions of an organism, e. g. , mood, growth and development, tissue function, and metabolism, as well as sending messages and acting on them. Human development is the process of Growing to maturity In biological terms this entails growth from a one-celled Zygote to an adult Human being Tissue is a cellular organizational level intermediate between cells and a complete organism Metabolism is the set of Chemical reactions that occur in living Organisms in order to maintain Life.

Types of signaling

The typical mode of cell signaling in the endocrine system is endocrine signaling. Cell signaling is part of a Complex system of Communication that governs basic cellular activities and coordinates cell actions The endocrine system is an integrated system of small organs that involve the release of extracellular signaling molecules known as Hormones The endocrine system is instrumental However, there are also other modes, i. e. , paracrine, autocrine, and neuroendocrine signaling [2]. Purely neurocrine signaling between neurons, on the other hand, belongs completely to the nervous system. Neurons (ˈnjuːɹɒn also known as neurones and nerve cells) are responsive cells in the Nervous system that process and transmit information The nervous system is a Network of specialized cells that communicate information about an animal's surroundings and itself

Endocrine

Main article: endocrine signaling

A number of glands that signal each other in sequence is usually referred to as an axis, for example the Hypothalamic-pituitary-adrenal axis. The endocrine system is an integrated system of small organs that involve the release of extracellular signaling molecules known as Hormones The endocrine system is instrumental The hypothalamic-pituitary-adrenal axis ( HPA or HTPA axis) also known as the Limbic -hypothalamic-pituitary-adrenal axis (LHPA axis is a complex set of direct influences

Typical endocrine glands are the pituitary, thyroid, and adrenal glands. The pituitary gland, or hypophysis, is an Endocrine gland about the size of a Pea. The thyroid is one of the largest Endocrine glands in the body In Mammals the adrenal glands (also known as suprarenal glands) are the triangle-shaped Endocrine glands that sit on top of the Kidneys their Features of endocrine glands are, in general, their ductless nature, their vascularity, and usually the presence of intracellular vacuoles or granules storing their hormones. In contrast exocrine glands such as salivary glands, sweat glands, and glands within the gastrointestinal tract tend to be much less vascular and have ducts or a hollow lumen. Exocrine glands are Glands that secrete their products ( Enzymes into ducts (duct glands The salivary glands in mammals are exocrine glands that produce saliva The skin contains two different groups of sweat glands: Apocrine sweat glands and Merocrine sweat glands. A gland is an organ in an animal's body that synthesizes a substance for release such as Hormones or Breast milk, often into the Bloodstream A lumen (Lat lūmen, an opening or light (pl lumina is the inside space or lining of a tubular structure such as an artery or intestine

Autocrine

Main article: Autocrine signalling

Other signaling can target the same cell. Autocrine signaling is a form of signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent that binds to autocrine receptors on the same cell leading

Paracrine

Main article: Paracrine signalling

Paracrine signaling is where the target cell is nearby. Paracrine signaling is a form of Cell signaling in which the target cell is near (" Para " = near the signal-releasing cell

Juxtacrine

Main article: Juxtacrine signalling

Juxtacrine signals are transmitted along cell membranes via protein or lipid components integral to the membrane and are capable of affecting either the emitting cell or cells immediately adjacent. In biology juxtacrine signaling is a type of Intercellular communication which is transmitted via Oligosaccharide, Lipid or Protein components

Role in disease

Main article: Endocrine diseases

Diseases of the endocrine system are common,[3] including diseases such as diabetes mellitus, thyroid disease, and obesity. Among the hundreds of endocrine diseases (or endocrinological diseases) are Adrenal disorders Adrenal insufficiency Among the hundreds of endocrine diseases (or endocrinological diseases) are Adrenal disorders Adrenal insufficiency Diabetes mellitus (ˌdaɪəˈbiːtiːz or /ˌdaɪəˈbiːtəs/ /məˈlaɪtəs/ or /ˈmɛlətəs/ often referred to simply as diabetes ( Ancient Greek: grc The thyroid is one of the largest Endocrine glands in the body Obesity is a condition in which excess Body fat has accumulated to such an extent that health may be negatively affected Endocrine disease is characterised by dysregulated hormone release (a productive Pituitary adenoma), inappropriate response to signalling (Hypothyroidism), lack or destruction of a gland (Diabetes mellitus type 1, diminished erythropoiesis in Chronic renal failure), or structural enlargement in a critical site such as the neck (Toxic multinodular goitre). Pituitary adenomas are Tumors that occur in the Pituitary gland, and account for about 10% of intracranial neoplasms. Hypothyroidism is the disease state in humans and animals caused by insufficient production of Thyroid hormone by the Thyroid gland. Diabetes mellitus type 1 (Type 1 diabetes Type I diabetes T1D T1DM IDDM juvenile diabetes is a form of Diabetes mellitus. Erythropoiesis is the process by which Red blood cells (erythrocytes are produced Chronic kidney disease (CKD also known as chronic renal disease, is a progressive loss of renal function over a period of months or years Toxic multinodular goitre (also known as toxic nodular goitre, toxic nodular struma) is a form of Hyperthyroidism - where there is excess production of Hypofunction of endocrine glands can occur as result of loss of reserve, hyposecretion, agenesis, atrophy, or active destruction. Hyperfunction can occur as result of hypersecretion, loss of suppression, hyperplastic, or neoplastic change, or hyperstimulation. Hyperplasia (or "hypergenesis" is a general term referring to the proliferation of cells within an organ or tissue beyond that which is ordinarily seen in e

Endocrinopathies are classified as primary, secondary, or tertiary. Primary endocrine disease inhibits the action of downstream glands. Tertiary endocrine disease is associated with dysfunction of the hypothalamus and its releasing hormones.

Cancer can occur in endocrine glands, such as the thyroid, and hormones have been implicated in signalling distant tissues to proliferate, for example the Estrogen receptor has been shown to be involved in certain breast cancers. Thyroid cancer refers to any of four kinds of malignant Tumors of the Thyroid gland papillary, follicular, medullary or The estrogen receptor (ER is a member of the nuclear hormone family of Intracellular receptors which is activated by the Hormone 17β-estradiol Breast cancer is a Cancer that starts in the cells of the Breast in women and men Endocrine, Paracrine, and autocrine signalling have all been implicated in proliferation, one of the required steps of oncogenesis. Oncogenesis is the process of Malignant transformation leading to the formation of a tumor ( Tumorigenesis) [4]

Table of endocrine glands and secreted hormones

This is a table of the glands of the endocrine system, and their secreted hormones

Hypothalamus

Secreted hormoneAbbreviationFrom cellsEffect
Thyrotropin-releasing hormoneTRHParvocellular neurosecretory neuronsRelease thyroid-stimulating hormone from anterior pituitary (primarily)
Stimulate prolactin release from anterior pituitary. The hypothalamus links the Nervous system to the Endocrine system via the Pituitary gland (hypophysis Thyrotropin-releasing hormone ( TRH) also called thyrotropin-releasing factor ( TRF) thyroliberin or protirelin, is a tropic The paraventricular nucleus (PVN is an aggregation of neurons in the Hypothalamus which produces many Hormones. Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a Peptide hormone synthesized and secreted by Thyrotrope cells in the The anterior pituitary (also called the adenohypophysis, from Greek adeno, "gland" hypo, "under" physis, "growth" Prolactin ( PRL) or Luteotropic hormone ( LTH) is a Peptide hormone primarily associated with Lactation. The anterior pituitary (also called the adenohypophysis, from Greek adeno, "gland" hypo, "under" physis, "growth"
Gonadotropin-releasing hormoneGnRHNeuroendocine cells of the Preoptic areaRelease of FSH and LH from anterior pituitary. Gonadotropin-releasing hormone ( GNRH) also known as Luteinizing-hormone releasing hormone ( LHRH) is a tropic Peptide Hormone The preoptic area is a region of the Hypothalamus. According to the MeSH classification it is considered part of the anterior hypothalamus Follicle-stimulating hormone ( FSH) is a Hormone synthesized and secreted by Gonadotropes in the Anterior pituitary gland. Luteinizing hormone ( LH, also known as lutropin) is a Hormone produced by the Anterior pituitary gland. The anterior pituitary (also called the adenohypophysis, from Greek adeno, "gland" hypo, "under" physis, "growth"
Growth hormone-releasing hormoneGHRHNeuroendocrine neurons of the Arcuate nucleusRelease GH from anterior pituitary
Corticotropin-releasing hormoneCRHParvocellular neurosecretory neuronsRelease ACTH from anterior pituitary
VasopressinParvocellular neurosecretory neuronsIncreases permeability of distal convoluted tubule and collecting duct to water in the nephrons of the kidney, thus increasing water reabsorbiton. Growth-hormone-releasing hormone (GHRH also known as growth-hormone-releasing factor (GRF or GHRF or somatocrinin, is a 44- Amino acid Peptide hormone The arcuate nucleus (or infundibular nucleus is an aggregation of Neurons in the mediobasal Hypothalamus, adjacent to the Third ventricle and the Median Growth hormone ( GH) is a Peptide hormone that stimulates growth and cell reproduction in humans and other animals The anterior pituitary (also called the adenohypophysis, from Greek adeno, "gland" hypo, "under" physis, "growth" Corticotropin-releasing hormone ( CRH) originally named corticotropin-releasing factor ( CRF) and also called corticoliberin, is a Polypeptide The paraventricular nucleus (PVN is an aggregation of neurons in the Hypothalamus which produces many Hormones. Adrenocorticotropic hormone ( ACTH or corticotropin) is a Polypeptide Hormone produced and secreted by the Pituitary gland The anterior pituitary (also called the adenohypophysis, from Greek adeno, "gland" hypo, "under" physis, "growth" Arginine vasopressin ( AVP) also known as vasopressin, argipressin or antidiuretic hormone ( ADH) is a Hormone found in The paraventricular nucleus (PVN is an aggregation of neurons in the Hypothalamus which produces many Hormones.
Somatostatin, also growth hormone-inhibiting hormoneSS or GHIHNeuroendocrince cells of the Periventricular nucleusInhibit release of GH and TSH from anterior pituitary
Prolactin inhibiting hormone or DopaminePIH or DADopamine neurons of the arcuate nucleusInhibit release of prolactin and TSH from anterior pituitary
Prolactin-releasing hormonePRHRelease prolactin from anterior pituitary

Pineal body

Secreted hormoneFrom cellsEffect
Melatonin (Primarily)Pinealocytesantioxidant and causes drowsiness

Pituitary gland (hypophysis)

Anterior pituitary lobe (adenohypophysis)

Secreted hormoneAbbreviationFrom cellsEffect
Growth hormoneGHSomatotropesstimulates growth and cell reproduction

Release Insulin-like growth factor 1 from liver

ProlactinPRLLactotropesmilk production in mammary glands
sexual gratification after sexual acts
Adrenocorticotropic hormone or corticotropinACTHCorticotropessynthesis of corticosteroids (glucocorticoids and androgens) in adrenocortical cells
LipotropinCorticotropeslipolysis and steroidogenesis,
stimulates melanocytes to produce melanin
Thyroid-stimulating hormone or thyrotropinTSHThyrotropesstimulates thyroid gland to secrete thyroxine (T4) and triiodothyronine (T3)
Follicle-stimulating hormoneFSHGonadotropesIn female: stimulates maturation of Graafian follicles in ovary. Somatostatin (also known as growth hormone inhibiting hormone ( GHIH) or somatotropin release-inhibiting factor ( SRIF) is a Peptide hormone The Periventricular nucleus is a composite structure of the Hypothalamus. Growth hormone ( GH) is a Peptide hormone that stimulates growth and cell reproduction in humans and other animals Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a Peptide hormone synthesized and secreted by Thyrotrope cells in the The anterior pituitary (also called the adenohypophysis, from Greek adeno, "gland" hypo, "under" physis, "growth" Dopamine is a Hormone and Neurotransmitter occurring in a wide variety of animals including both vertebrates and invertebrates The arcuate nucleus (or infundibular nucleus is an aggregation of Neurons in the mediobasal Hypothalamus, adjacent to the Third ventricle and the Median Prolactin ( PRL) or Luteotropic hormone ( LTH) is a Peptide hormone primarily associated with Lactation. Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a Peptide hormone synthesized and secreted by Thyrotrope cells in the The anterior pituitary (also called the adenohypophysis, from Greek adeno, "gland" hypo, "under" physis, "growth" Prolactin ( PRL) or Luteotropic hormone ( LTH) is a Peptide hormone primarily associated with Lactation. The anterior pituitary (also called the adenohypophysis, from Greek adeno, "gland" hypo, "under" physis, "growth" The pineal gland (also called the pineal body, epiphysis cerebri, or epiphysis) is a small endocrine gland in the vertebrate Brain Melatonin is a naturally occurring Hormone found in most animals including humans and some other living organisms including Algae. Pinealocytes are the main cells of the Pineal gland. They produce and secrete Melatonin. An antioxidant is a Molecule capable of slowing or preventing the oxidation of other molecules Somnolence (or " drowsiness " is a state of near- Sleep, a strong desire for sleep or sleeping for unusually long periods (c The pituitary gland, or hypophysis, is an Endocrine gland about the size of a Pea. The anterior pituitary (also called the adenohypophysis, from Greek adeno, "gland" hypo, "under" physis, "growth" Growth hormone ( GH) is a Peptide hormone that stimulates growth and cell reproduction in humans and other animals Somatotropes are cells in the Anterior pituitary which produce Growth hormone. Human development is the process of Growing to maturity In biological terms this entails growth from a one-celled Zygote to an adult Human being The cell is the structural and functional unit of all known living Organisms It is the smallest unit of an organism that is classified as living and is often called Insulin-like growth factor 1 (IGF-1 that was once called somatomedin C is a Polypeptide Protein Hormone similar in Molecular structure The liver is a vital organ in the human body and is present in Vertebrates and some other animals Prolactin ( PRL) or Luteotropic hormone ( LTH) is a Peptide hormone primarily associated with Lactation. Lactotrophs (also known as lactotrope mammatroph mammotroph epsilon acidophil prolactin cell and lactotropic cell are cells in the Anterior pituitary which produce Mammary glands are the organs that in Mammals produce Milk for the sustenance of the young An orgasm (sexual climax is the conclusion of the plateau phase of the sexual response cycle, and may be experienced by both males and females Human sexual behavior or different human sexual practices encompass a wide range of activities such as strategies to find or attract partners ( Mating and display Adrenocorticotropic hormone ( ACTH or corticotropin) is a Polypeptide Hormone produced and secreted by the Pituitary gland Corticotropes (or corticotrophs are cells in the Anterior pituitary which produce Adrenocorticotrophic hormone and Melanocyte stimulating hormone Corticosteroids are a class of Steroid hormones that are produced in the Adrenal cortex. Glucocorticoids (GC are a class of Steroid hormones characterised by an ability to bind with the glucocorticoid receptor ( GR) and trigger similar effects Androgen is the generic term for any natural or synthetic compound usually a Steroid Hormone, that stimulates or controls the development and maintenance of masculine Situated along the perimeter of the Adrenal gland, the adrenal cortex mediates the stress response through the production of Mineralocorticoids and Glucocorticoids Lipotropin is a Hormone produced by the cleavage of Pro-opiomelanocortin (POMC Corticotropes (or corticotrophs are cells in the Anterior pituitary which produce Adrenocorticotrophic hormone and Melanocyte stimulating hormone Lipolysis is the breakdown of fat stored in fat cells During this process Free fatty acids are released into the bloodstream and circulate throughout the body Steroid metabolism is the complete set of Chemical reactions in organisms that produce modify and consume Steroids These Metabolic pathways include Melanocytes are cells located in the bottom layer (the Stratum basale) of the skin's epidermis and in the middle layer of the eye (the Uvea) Melanin is a class of compounds found in the Plant, Animal and Protista kingdoms, where it serves predominantly as a Pigment. Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a Peptide hormone synthesized and secreted by Thyrotrope cells in the Thyrotropes are cells in the Anterior pituitary which produce Thyroid stimulating hormone. The thyroid is one of the largest Endocrine glands in the body Thyroxine, or 353'5'-tetra­iodothyronine (often abbreviated as T4) a form of Thyroid hormones is the major Hormone secreted by the Triiodothyronine, C15[[hydrogen H12]] I3[[nitrogen N]] O4, also known as T3, is a Thyroid Follicle-stimulating hormone ( FSH) is a Hormone synthesized and secreted by Gonadotropes in the Anterior pituitary gland. Gonadotropes are basophilic cells in the Anterior pituitary which produce the Gonadotropins Follicle-stimulating hormone (FSH and Ovarian follicle is the basic unit of female reproductive biology and is composed of a roughly spherical aggregations of cells found in the Ovary. "Ovaria" redirects here This is also a proposed section and a Synonym of Solanum.

In male: spermatogenesis, enhances production of androgen-binding protein by the Sertoli cells of the testes

Luteinizing hormoneLHGonadotropesIn female: ovulation

In male: stimulates Leydig cell production of testosterone

Posterior pituitary lobe (neurohypophysis)

Secreted hormoneAbbreviationFrom cellsEffect
OxytocinMagnocellular neurosecretory cellsContraction of cervix and vagina

Involved in orgasm, trust between people. Spermatogenesis is the process by which male Spermatogonia develop into mature Spermatozoa. Androgen-binding protein ( ABP) is a Glycoprotein (beta- Globulin) produced by the Sertoli cells in the Seminiferous tubules of A Sertoli cell (a kind of Sustentacular cell) is a 'nurse' cell of the testes which is part of a Seminiferous tubule. The testicle (from Latin testiculus, diminutive of testis, meaning "witness" virility plural testes) is the male Luteinizing hormone ( LH, also known as lutropin) is a Hormone produced by the Anterior pituitary gland. Gonadotropes are basophilic cells in the Anterior pituitary which produce the Gonadotropins Follicle-stimulating hormone (FSH and Note This article deals primarily with Human ovulation nonhuman Animal ovulation is touched on briefly at the conclusion Leydig cells, also known as interstitial cells of Leydig, are found adjacent to the Seminiferous tubules in the testicle. Testosterone is a Steroid hormone from the Androgen group In mammals testosterone is primarily secreted in the testes of males and the Ovaries The posterior pituitary (or neurohypophysis) comprises the Posterior lobe of the Pituitary gland and is part of the Endocrine system. Oxytocin ( IPA: /ˌɔksɪˈtoʊsɪn/ (Greek "quick birth" is a Mammalian Hormone that also acts as a Neurotransmitter in the Magnocellular neurosecretory cells are large cells within the Supraoptic nucleus and Paraventricular nucleus of the Hypothalamus. The cervix (from Latin "neck" is the lower narrow portion of the Uterus where it joins with the top end of the Vagina. The vagina (from Latin, literally " Sheath " or " Scabbard " is a fibromuscular tubular tract leading from the Uterus An orgasm (sexual climax is the conclusion of the plateau phase of the sexual response cycle, and may be experienced by both males and females [5] and circadian homeostasis (body temperature, activity level, wakefulness) [6]. release breast milk

Vasopressin or antidiuretic hormoneAVP or ADHMagnocellular neurosecretory cellsretention of water in kidneys

moderate vasoconstriction

Oxytocin and Anti-Diuretic Hormone are not secreted in the posterior lobe, merely stored. Arginine vasopressin ( AVP) also known as vasopressin, argipressin or antidiuretic hormone ( ADH) is a Hormone found in Magnocellular neurosecretory cells are large cells within the Supraoptic nucleus and Paraventricular nucleus of the Hypothalamus. The kidneys are complicated organs that have numerous biological roles Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels particularly the large Arteries, Arterioles

Intermediate pituitary lobe (pars intermedia)

Secreted hormoneAbbreviationFrom cellsEffect
Melanocyte-stimulating hormoneMSHMelanotrophmelanogenesis by melanocytes in skin and hair. Pars intermedia is the boundary between the anterior and posterior lobes of the Pituitary. The melanocyte-stimulating hormones (collectively referred to as MSH) are a class of Peptide hormones produced by cells in the Intermediate lobe of A Melanotroph (or melanotrope) is a cell in the Pituitary gland which generates Melanocyte-stimulating hormone from its precursor Proopiomelanocortin Melanocytes are cells located in the bottom layer (the Stratum basale) of the skin's epidermis and in the middle layer of the eye (the Uvea) Melanocytes are cells located in the bottom layer (the Stratum basale) of the skin's epidermis and in the middle layer of the eye (the Uvea) The skin is the outer covering of living tissue of an animal (or plant Hair is a keratinised protein filament that grows through the epidermis from follicles deep within the Dermis.

Thyroid

Secreted hormoneAbbreviationFrom cellsEffect
TriiodothyronineT3Thyroid epithelial cellpotent form of thyroid hormone: increase the basal metabolic rate & sensitivity to catecholamines,

affect protein synthesis

Thyroxine or tetraiodothyronineT4Thyroid epithelial cellsless active form of thyroid hormone: increase the basal metabolic rate & sensitivity to catecholamines,

affect protein synthesis, often functions as a prohormone

CalcitoninParafollicular cellsConstruct bone

reduce blood Ca2+

Parathyroid

Secreted hormoneAbbreviationFrom cellsEffect
Parathyroid hormonePTHParathyroid chief cellincrease blood Ca2+: *indirectly stimulate osteoclasts

(Slightly) decrease blood phosphate:

  • (decreased reuptake in kidney but increased uptake from bones
  • activate vitamin D)

Heart

Secreted hormoneAbbreviationFrom cellsEffect
Atrial-natriuretic peptideANPCardiac myocytesReduce blood pressure by:

reducing systemic vascular resistance, reducing blood water, sodium and fats

Brain natriuretic peptideBNPCardiac myocytes(To a minor degree than ANP) reduce blood pressure by:

reducing systemic vascular resistance, reducing blood water, sodium and fats

Striated muscle

Secreted hormoneFrom cellsEffect
ThrombopoietinMyocytesstimulates megakaryocytes to produce platelets[7]

Skin

Secreted hormoneFrom cellsEffect
Calcidiol (25-hydroxyvitamin D3)Inactive form of Vitamin D3

Adipose tissue

Secreted hormoneFrom cellsEffect
Leptin (Primarily)Adipocytesdecrease of appetite and increase of metabolism. The thyroid is one of the largest Endocrine glands in the body Triiodothyronine, C15[[hydrogen H12]] I3[[nitrogen N]] O4, also known as T3, is a Thyroid Thyroid epithelial cells (also called follicular cells or principal cells) are cells in the Thyroid gland that produce and secrete Thyroxine The thyroid hormones, Thyroxine ( T4) and Triiodothyronine ( T3) are Tyrosine -based Hormones produced Basal metabolic rate ( BMR) is the amount of energy expended while at rest in a neutrally temperate environment in the post-absorptive state (meaning that the digestive system Protein synthesis is the creation of proteins using DNA and' RNA'. Thyroxine, or 353'5'-tetra­iodothyronine (often abbreviated as T4) a form of Thyroid hormones is the major Hormone secreted by the Thyroid epithelial cells (also called follicular cells or principal cells) are cells in the Thyroid gland that produce and secrete Thyroxine The thyroid hormones, Thyroxine ( T4) and Triiodothyronine ( T3) are Tyrosine -based Hormones produced Basal metabolic rate ( BMR) is the amount of energy expended while at rest in a neutrally temperate environment in the post-absorptive state (meaning that the digestive system Protein synthesis is the creation of proteins using DNA and' RNA'. A prohormone is a substance that is a precursor to a Hormone, usually having minimal hormonal effect by itself Calcitonin is a 32-amino acid linear polypeptide Hormone that is produced in Humans primarily by the parafollicular (also known as C-cells of the Parafollicular cells (also called C cells) are cells in the Thyroid which produce and secrete Calcitonin. Calcium (ˈkælsiəm is the Chemical element with the symbol Ca and Atomic number 20 The parathyroid glands are small endocrine Glands in the neck usually located behind the Thyroid gland, which produce Parathyroid hormone. Parathyroid hormone (PTH, or parathormone, is secreted by the Parathyroid glands as a Polypeptide containing 84 Amino acids. Parathyroid chief cells are cells in the Parathyroid glands which produce Parathyroid hormone. Calcium (ˈkælsiəm is the Chemical element with the symbol Ca and Atomic number 20 An osteoclast (from the Greek words for "bone" and "broken" is a type of Bone cell that removes Bone tissue by removing its Mineralized matrix The kidneys are complicated organs that have numerous biological roles Vitamin D is a group of fat-soluble Prohormones, the two major forms of which are vitamin D2 (or Ergocalciferol) and vitamin D3 (or A phosphate, an Inorganic chemical, is a salt of Phosphoric acid. The kidneys are complicated organs that have numerous biological roles Vitamin D is a group of fat-soluble Prohormones, the two major forms of which are vitamin D2 (or Ergocalciferol) and vitamin D3 (or The heart is a muscular organ in all Vertebrates responsible for pumping Blood through the Blood vessels by repeated rhythmic Atrial natriuretic peptide ( ANP) atrial natriuretic factor ( ANF) or atriopeptin, is a protein ( Polypeptide) Hormone secreted The cardiac muscle is a type of involuntary striated Muscle found in the walls of the Heart. Blood pressure is also the title of a short story by Damon Runyan in Guys and Dolls and Other Stories Systemic circulation is the portion of the Cardiovascular system which carries Oxygenated Blood away from the heart to the Body, and returns Vascular resistance is a term used to define the resistance to flow that must be overcome to push Blood through the Circulatory system. Blood lipids (or blood fats are Lipids in the Blood, either free or bound to other molecules Brain natriuretic peptide (BNP also known as B-type natriuretic peptide (also BNP or GC-B, is a 32 amino acid polypeptide secreted by the ventricles The cardiac muscle is a type of involuntary striated Muscle found in the walls of the Heart. Blood pressure is also the title of a short story by Damon Runyan in Guys and Dolls and Other Stories Systemic circulation is the portion of the Cardiovascular system which carries Oxygenated Blood away from the heart to the Body, and returns Vascular resistance is a term used to define the resistance to flow that must be overcome to push Blood through the Circulatory system. Blood lipids (or blood fats are Lipids in the Blood, either free or bound to other molecules Striated muscle is a form of fibres that are combined into parallel fibres Thrombopoietin (leukemia virus oncogene ligand megakaryocyte growth and development factor, also known as THPO, is a Glycoprotein Hormone produced A myocyte (also known as a myocardial cell is the type of cell found in heart muscles. The megakaryocyte is a Bone marrow cell responsible for the production of blood Platelets necessary for normal blood Clotting Megakaryocytes normally Platelets, or Thrombocytes, are small cytoplasmic bodies derived from cells They circulate in the Blood of Mammals and are involved The skin is the outer covering of living tissue of an animal (or plant Calcidiol, calcifediol, 25-hydroxycholecalciferol, or 25–hydroxy–vitamin D, is a Prehormone which is produced by the Hepatic Cholecalciferol is a form of Vitamin D, also called vitamin D3. "Adipose" redirects here For the Doctor Who monster see " Partners in Crime " Leptin (Greek leptos meaning thin is a 16 kDa Adipocytes are the cells that primarily compose Adipose tissue, specialized in storing energy as Fat. Metabolism is the set of Chemical reactions that occur in living Organisms in order to maintain Life.
Estrogens[8] (mainly Estrone)Adipocytes

Stomach

Secreted hormoneAbbreviationFrom cellsEffect
Gastrin (Primarily)G cellsSecretion of gastric acid by parietal cells
GhrelinP/D1 cellsStimulate appetite,

secretion of growth hormone from anterior pituitary gland

Neuropeptide YNPYincreased food intake and decreased physical activity
SecretinS cellsSecretion of bicarbonate from liver, pancreas and duodenal Brunner's glands

Enhances effects of cholecystokinin Stops production of gastric juice

SomatostatinD cellsSuppress release of gastrin, cholecystokinin (CCK), secretin, motilin, vasoactive intestinal peptide (VIP), gastric inhibitory polypeptide (GIP), enteroglucagon

Lowers rate of gastric emptying Reduces smooth muscle contractions and blood flow within the intestine [9]

HistamineECL cellsstimulate gastric acid secretion
EndothelinX cellsSmooth muscle contraction of stomach [10]

Duodenum

Secreted hormoneFrom cellsEffect
CholecystokininI cellsRelease of digestive enzymes from pancreas

Release of bile from gallbladder, hunger suppressant

Liver

Secreted hormoneAbbreviationFrom cellsEffect
Insulin-like growth factor (or somatomedin) (Primarily)IGFHepatocytesinsulin-like effects

regulate cell growth and development

Angiotensinogen and angiotensinHepatocytesvasoconstriction

release of aldosterone from adrenal cortex dipsogen. Estrogens (US otherwise oestrogens or œstrogens) are a group of Steroid compounds named for their importance in the Estrous cycle, Estrone (also oestrone) is an Estrogenic Hormone secreted by the Ovary. Adipocytes are the cells that primarily compose Adipose tissue, specialized in storing energy as Fat. In Human anatomy, the stomach is a J-shaped hollow muscular organ of the Gastrointestinal tract involved in the second phase of Digestion, following In humans gastrin is a Hormone that stimulates secretion of Gastric acid (HCl by the Parietal cells of the Stomach, as well as aiding in In Anatomy, the G cell is a type of cell in the stomach that secretes Gastrin. Gastric acid is one of the main Secretions of the Stomach, together with several Enzymes and Intrinsic factor. Parietal cells (also called oxyntic cells) are the Stomach Epithelium cells that secrete Gastric acid and Intrinsic factor Ghrelin is a Hormone produced mainly by P/D1 cells lining the fundus of the human Stomach and epsilon cells of the Pancreas that stimulates Cells lining the fundus of the human Stomach that produce Ghrelin. Growth hormone ( GH) is a Peptide hormone that stimulates growth and cell reproduction in humans and other animals The anterior pituitary (also called the adenohypophysis, from Greek adeno, "gland" hypo, "under" physis, "growth" Neuropeptide Y (NPY is a 36 Amino acid peptide Neurotransmitter found in the Brain and Autonomic nervous system. Secretin is a Peptide hormone produced in the S cells of the Duodenum in the Crypts of Lieberkühn. S cells are cells which release Secretin, found in the Jejunum and Duodenum. In Inorganic chemistry, bicarbonate ( IUPAC -recommended nomenclature hydrogencarbonate) is an intermediate form in the Deprotonation The liver is a vital organ in the human body and is present in Vertebrates and some other animals The pancreas is a Gland organ in the digestive and Endocrine system of Vertebrates. Brunner glands (or Pancreal glands) are compound tubular submucosal Glands found in that portion of the Duodenum which is above the Cholecystokinin ( CCK; from Greek chole, "bile" cysto, "sac" kinin, "move" hence move the bile-sac Somatostatin (also known as growth hormone inhibiting hormone ( GHIH) or somatotropin release-inhibiting factor ( SRIF) is a Peptide hormone In humans gastrin is a Hormone that stimulates secretion of Gastric acid (HCl by the Parietal cells of the Stomach, as well as aiding in Cholecystokinin ( CCK; from Greek chole, "bile" cysto, "sac" kinin, "move" hence move the bile-sac Secretin is a Peptide hormone produced in the S cells of the Duodenum in the Crypts of Lieberkühn. Motilin is a Polypeptide hormone secreted by M cells of the Small intestine that increases the Migrating myoelectric complex component Vasoactive intestinal peptide ( VIP, also polypeptide) is a Peptide hormone containing 28 Amino acid residues and is produced in many Gastric inhibitory polypeptide ( GIP) also known as the glucose-dependent insulinotropic peptide is a member of the secretin family of Hormones Enteroglucagon is a Peptide Hormone derived from Preproglucagon. Smooth muscle is a type of non- Striated muscle, found within the Tunica media layer of large and small Arteries and Veins, the bladder Histamine is a Biogenic amine involved in local immune responses as well as regulating physiological function in the gut and acting as a Neurotransmitter Enterochromaffin-like cells or ECL cells are a type of Neuroendocrine cells found in the gastric glands of the Gastric mucosa beneath the Epithelium Gastric acid is one of the main Secretions of the Stomach, together with several Enzymes and Intrinsic factor. Endothelins are proteins that constrict blood vessels and raise blood pressure Smooth muscle is a type of non- Striated muscle, found within the Tunica media layer of large and small Arteries and Veins, the bladder In Anatomy of the Digestive system, the duodenum is a hollow jointed tube about 25-30 cm (10-12 in long connecting the Stomach to the Jejunum Cholecystokinin ( CCK; from Greek chole, "bile" cysto, "sac" kinin, "move" hence move the bile-sac Cholecystokinin ( CCK; from Greek chole, "bile" cysto, "sac" kinin, "move" hence move the bile-sac Enzymes are Biomolecules that catalyze ( ie increase the rates of Chemical reactions Almost all enzymes are Proteins The pancreas is a Gland organ in the digestive and Endocrine system of Vertebrates. Bile or gall is a bitter yellow or green Alkaline fluid secreted by Hepatocytes from the Liver of most Vertebrates In many species Hunger is a feeling experienced usually followed by a desire to Eat. The liver is a vital organ in the human body and is present in Vertebrates and some other animals The insulin-like growth factors (IGFs are Polypeptides with high sequence similarity to Insulin. Hepatocytes make up 70-80% of the Cytoplasmic mass of the Liver. The term cell growth is used in two different ways in Biology. Angiotensin causes blood vessels to constrict and drives blood pressure up Angiotensin causes blood vessels to constrict and drives blood pressure up Hepatocytes make up 70-80% of the Cytoplasmic mass of the Liver. Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels particularly the large Arteries, Arterioles Aldosterone is a hormone that causes the tubules of the kidneys to retain sodium and water Situated along the perimeter of the Adrenal gland, the adrenal cortex mediates the stress response through the production of Mineralocorticoids and Glucocorticoids A dipsogen is an agent that causes Thirst. (From Greek dypsa, "thirst" and the suffix -gen, "to create"

ThrombopoietinHepatocytesstimulates megakaryocytes to produce platelets[7]

Pancreas

Secreted hormoneFrom cellsEffect
Insulin (Primarily)ß Islet cellsIntake of glucose, glycogenesis and glycolysis in liver and muscle from blood

intake of lipids and synthesis of triglycerides in adipocytes Other anabolic effects

Glucagon (Also Primarily)a Islet cellsglycogenolysis and gluconeogenesis in liver

increases blood glucose level

Somatostatind Islet cellsInhibit release of insulin [11]

Inhibit release of glucagon[11] Suppress the exocrine secretory action of pancreas. Thrombopoietin (leukemia virus oncogene ligand megakaryocyte growth and development factor, also known as THPO, is a Glycoprotein Hormone produced Hepatocytes make up 70-80% of the Cytoplasmic mass of the Liver. The megakaryocyte is a Bone marrow cell responsible for the production of blood Platelets necessary for normal blood Clotting Megakaryocytes normally Platelets, or Thrombocytes, are small cytoplasmic bodies derived from cells They circulate in the Blood of Mammals and are involved The pancreas is a Gland organ in the digestive and Endocrine system of Vertebrates. Insulin is a Hormone with intensive effects on both metabolism and several other body systems (eg vascular compliance Beta cells ( beta-cells, β-cells) are a type of cell in the Pancreas in areas called the Islets of Langerhans. Glucose (Glc a Monosaccharide (or simple Sugar) also known as grape sugar, is an important Carbohydrate in Biology. Glycogenesis is the process of Glycogen synthesis in which Glucose molecules are added to chains of glycogen See also Gluconeogenesis, which carries out a process wherein glucose is synthesized rather than catabolized The liver is a vital organ in the human body and is present in Vertebrates and some other animals Muscle (from Latin musculus, diminutive of mus "mouse" is contractile tissue of the body and is derived from the Lipids are broadly defined as any fat- Soluble ( lipophilic) naturally-occurring Molecule, such as fats oils waxes cholesterol sterols fat-soluble (more properly known as, TAG or triacylglyceride) is Glyceride in which the Glycerol is Esterified with three Fatty acids It is the Adipocytes are the cells that primarily compose Adipose tissue, specialized in storing energy as Fat. Anabolism is the set of Metabolic pathways that construct molecules from smaller units Glucagon is an important Hormone involved in Carbohydrate metabolism. Alpha cells are endocrine cells in the Islets of Langerhans of the Pancreas. Glycogenolysis (also known as "Glycogenlysis" is the Catabolism of Glycogen by removal of a Glucose monomer through cleavage with inorganic Gluconeogenesis (abreviated GNG) is a Metabolic pathway that results in the generation of Glucose from non- Carbohydrate carbon substrates such The liver is a vital organ in the human body and is present in Vertebrates and some other animals Somatostatin (also known as growth hormone inhibiting hormone ( GHIH) or somatotropin release-inhibiting factor ( SRIF) is a Peptide hormone Delta cells (δ-cells or D cells are Somatostatin producing cells They can be found in the Stomach, Intestine and the Islets of Langerhans Insulin is a Hormone with intensive effects on both metabolism and several other body systems (eg vascular compliance Glucagon is an important Hormone involved in Carbohydrate metabolism. The pancreas is a Gland organ in the digestive and Endocrine system of Vertebrates.

Pancreatic polypeptidePP cellsUnknown

Kidney

Secreted hormoneFrom cellsEffect
Renin (Primarily)Juxtaglomerular cellsActivates the renin-angiotensin system by producing angiotensin I of angiotensinogen
Erythropoietin (EPO)Extraglomerular mesangial cellsStimulate erythrocyte production
Calcitriol (1,25-dihydroxyvitamin D3)Active form of vitamin D3

Increase absorption of calcium and phosphate from gastrointestinal tract and kidneys inhibit release of PTH

Thrombopoietinstimulates megakaryocytes to produce platelets[7]

Adrenal glands

Adrenal cortex

Secreted hormoneFrom cellsEffect
Glucocorticoids (chiefly cortisol)zona fasciculata and zona reticularis cellsStimulation of gluconeogenesis

Inhibition of glucose uptake in muscle and adipose tissue Mobilization of amino acids from extrahepatic tissues Stimulation of fat breakdown in adipose tissue anti-inflammatory and immunosuppressive

Mineralocorticoids (chiefly aldosterone)Zona glomerulosa cellsIncrease blood volume by reabsorption of sodium in kidneys (primarily)

Potassium and H+ secretion in kidney. Pancreatic polypeptide is a Polypeptide secreted by PP cells in the Endocrine pancreas predominantly in the Head of the pancreas. PP cells (F cells are Pancreatic polypeptide producing cells in the Islets of Langerhans in the Pancreas. The kidneys are complicated organs that have numerous biological roles Renin (pronounced "Ree-nin" or "Rē-nin" (ˈriːnɨn also known as Angiotensinogenase, is a circulating Enzyme that participates in the body's In the Kidney, the juxtaglomerular cells ( JG cells, also known as granular cells) are cells that synthesize store and secrete the enzyme Renin The renin-angiotensin system (RAS or the renin-angiotensin-aldosterone system (RAAS is a hormone system that regulates Blood pressure and water ( fluid Angiotensin causes blood vessels to constrict and drives blood pressure up Angiotensin causes blood vessels to constrict and drives blood pressure up Erythropoietin (ɨˌɹɪθɹoʊˈpɔɪɨtɨn /ɨˌɹɪθɹoʊˈpɔɪtən/ or /ɨˌɹiːθɹoʊ-/ or EPO is a Glycoprotein Hormone that controls Extraglomerular mesangial cells (or lacis cells) are light-staining cells in the Kidney found outside the Glomerulus, near the Vascular pole Red blood cells are the most common type of Blood cell and the Vertebrate body's principal means of delivering Oxygen to the body tissues via the Blood Calcitriol ( INN) (ˌkælsɨˈtraɪɒl/ /ˌkælˈsɨtriːɒl or 125-dihydroxycholecalciferol (abbreviated 125-(OH2D3) (also Cholecalciferol is a form of Vitamin D, also called vitamin D3. Calcium (ˈkælsiəm is the Chemical element with the symbol Ca and Atomic number 20 A phosphate, an Inorganic chemical, is a salt of Phosphoric acid. The kidneys are complicated organs that have numerous biological roles Parathyroid hormone (PTH, or parathormone, is secreted by the Parathyroid glands as a Polypeptide containing 84 Amino acids. Thrombopoietin (leukemia virus oncogene ligand megakaryocyte growth and development factor, also known as THPO, is a Glycoprotein Hormone produced The megakaryocyte is a Bone marrow cell responsible for the production of blood Platelets necessary for normal blood Clotting Megakaryocytes normally Platelets, or Thrombocytes, are small cytoplasmic bodies derived from cells They circulate in the Blood of Mammals and are involved In Mammals the adrenal glands (also known as suprarenal glands) are the triangle-shaped Endocrine glands that sit on top of the Kidneys their Situated along the perimeter of the Adrenal gland, the adrenal cortex mediates the stress response through the production of Mineralocorticoids and Glucocorticoids Glucocorticoids (GC are a class of Steroid hormones characterised by an ability to bind with the glucocorticoid receptor ( GR) and trigger similar effects Cortisol is a Corticosteroid Hormone produced by the Adrenal gland (in the Zona fasciculata of the Adrenal cortex) Cells of the zona fasciculata sit directly beneath the Zona glomerulosa and are organized in bundles (or Fascicles) The zona reticularis is the innermost layer of the Adrenal cortex, lying deep to the Zona fasciculata and superficial to the Adrenal medulla. Gluconeogenesis (abreviated GNG) is a Metabolic pathway that results in the generation of Glucose from non- Carbohydrate carbon substrates such "Adipose" redirects here For the Doctor Who monster see " Partners in Crime " In Chemistry, an amino acid is a Molecule containing both Amine and Carboxyl Functional groups In Biochemistry, this Fatty acid degradation is the process in which Fatty acids are broken down into their metabolites resulting in release of its energy to the target cells Anti-inflammatory refers to the property of a substance or treatment that reduces Inflammation. Immunosuppression involves an act that reduces the activation or Efficacy of the Immune system. Mineralocorticoids are a class of Steroid hormones characterised by their similarity to Aldosterone and their influence on salt and water balance Aldosterone is a hormone that causes the tubules of the kidneys to retain sodium and water The zona glomerulosa of the Adrenal gland is the most superficial layer of the adrenal cortex lying directly beneath the adrenal gland's capsule Blood volume is the Volume of Blood (both Red blood cells and plasma) in a person's Circulatory system. Sodium (ˈsoʊdiəm is an element which has the symbol Na( Latin natrium, from Arabic natrun) atomic number 11 atomic mass 22 The kidneys are complicated organs that have numerous biological roles Potassium (pəˈtæsiəm is a Chemical element. It has the symbol K (kalium from qalīy Atomic number 19 and Atomic mass 39 Hydrogen ion is recommended by IUPAC as a general term for all Ions of Hydrogen and its Isotopes Depending on the Charge of the ion

Androgens (including DHEA and testosterone)Zona fasciculata and Zona reticularis cellsVirilization, anabolic

Adrenal medulla

Secreted hormoneFrom cellsEffect
Adrenaline (epinephrine) (Primarily)Chromaffin cellsFight-or-flight response:
  • Boost the supply of oxygen and glucose to the brain and muscles (by increasing heart rate and stroke volume, vasodilation, increasing catalysis of glycogen in liver, breakdown of lipids in fat cells)
  • Dilate the pupils
  • Suppress non-emergency bodily processes (e. Androgen is the generic term for any natural or synthetic compound usually a Steroid Hormone, that stimulates or controls the development and maintenance of masculine Dehydroepiandrosterone ( DHEA) is a natural Steroid Prohormone produced from Cholesterol by the Adrenal glands the Gonads Testosterone is a Steroid hormone from the Androgen group In mammals testosterone is primarily secreted in the testes of males and the Ovaries Cells of the zona fasciculata sit directly beneath the Zona glomerulosa and are organized in bundles (or Fascicles) The zona reticularis is the innermost layer of the Adrenal cortex, lying deep to the Zona fasciculata and superficial to the Adrenal medulla. In biology and medicine virilization refers to the biological development of Sex differences, changes which make a Male body different from a Female body Anabolism is the set of Metabolic pathways that construct molecules from smaller units The adrenal medulla is part of the Adrenal gland. It is located at the center of the gland being surrounded by the Adrenal cortex. Chromaffin cells are Neuroendocrine cells found in the medulla of the Adrenal gland (suprarenal gland - located above the kidneys and in other ganglia The fight-or-flight response', also called the fright, fight or flight response, hyperarousal or the acute stress response, was first Oxygen (from the Greek roots ὀξύς (oxys (acid literally "sharp" from the taste of acids and -γενής (-genēs (producer literally begetteris the Glucose (Glc a Monosaccharide (or simple Sugar) also known as grape sugar, is an important Carbohydrate in Biology. The brain is the center of the Nervous system in animals All Vertebrates and the majority of Invertebrates have a brain Muscle (from Latin musculus, diminutive of mus "mouse" is contractile tissue of the body and is derived from the Measuring heart rate The Pulse rate (which in most people is identical to the heart rate can be measured at any point on the body where an Artery 's pulsation Stroke volume (SV is the volume of Blood pumped by the right/ Left ventricle of the heart in one contraction. Catalysis is the process in which the rate of a Chemical reaction is increased by means of a Chemical substance known as a catalyst Glycogen is a Polysaccharide of Glucose (Glc which functions as the secondary short term energy storage in Animal cells Lipids are broadly defined as any fat- Soluble ( lipophilic) naturally-occurring Molecule, such as fats oils waxes cholesterol sterols fat-soluble Adipocytes are the cells that primarily compose Adipose tissue, specialized in storing energy as Fat. The pupil is the hole that is located in the center of the iris of the eye and that controls the amount of light that enters the Eye. g. , digestion)
  • Suppress immune system
Noradrenaline (norepinephrine)Chromaffin cellsFight-or-flight response:
  • Boost the supply of oxygen and glucose to the brain and muscles (by increasing heart rate and stroke volume, vasoconstriction and increased blood pressure, breakdown of lipids in fat cells)
  • Increase skeletal muscle readiness. Digestion is the breaking down of chemicals in the body into a form that can be absorbed An immune system is a collection of mechanisms within an Organism that protects against Disease by identifying and killing Pathogens and Tumor Norepinephrine ( INN) (abbreviated norepi or NE) or noradrenaline ( BAN) (abbreviated NA or NAd) is a Chromaffin cells are Neuroendocrine cells found in the medulla of the Adrenal gland (suprarenal gland - located above the kidneys and in other ganglia The fight-or-flight response', also called the fright, fight or flight response, hyperarousal or the acute stress response, was first Oxygen (from the Greek roots ὀξύς (oxys (acid literally "sharp" from the taste of acids and -γενής (-genēs (producer literally begetteris the Glucose (Glc a Monosaccharide (or simple Sugar) also known as grape sugar, is an important Carbohydrate in Biology. The brain is the center of the Nervous system in animals All Vertebrates and the majority of Invertebrates have a brain Muscle (from Latin musculus, diminutive of mus "mouse" is contractile tissue of the body and is derived from the Measuring heart rate The Pulse rate (which in most people is identical to the heart rate can be measured at any point on the body where an Artery 's pulsation Stroke volume (SV is the volume of Blood pumped by the right/ Left ventricle of the heart in one contraction. Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels particularly the large Arteries, Arterioles Blood pressure is also the title of a short story by Damon Runyan in Guys and Dolls and Other Stories Lipids are broadly defined as any fat- Soluble ( lipophilic) naturally-occurring Molecule, such as fats oils waxes cholesterol sterols fat-soluble Adipocytes are the cells that primarily compose Adipose tissue, specialized in storing energy as Fat. Skeletal muscle is a type of Striated muscle, which usually attaches to tendons
DopamineChromaffin cellsIncrease heart rate and blood pressure
EnkephalinChromaffin cellsRegulate pain
Secreted hormoneFrom cellsEffect
Androgens (chiefly testosterone)Leydig cellsAnabolic: growth of muscle mass and strength, increased bone density, growth and strength,

Virilizing: maturation of sex organs, formation of scrotum, deepening of voice, growth of beard and axillary hair. Dopamine is a Hormone and Neurotransmitter occurring in a wide variety of animals including both vertebrates and invertebrates Chromaffin cells are Neuroendocrine cells found in the medulla of the Adrenal gland (suprarenal gland - located above the kidneys and in other ganglia The heart is a muscular organ in all Vertebrates responsible for pumping Blood through the Blood vessels by repeated rhythmic Blood pressure is also the title of a short story by Damon Runyan in Guys and Dolls and Other Stories An enkephalin is a Pentapeptide involved in regulating Pain and Nociception in the body Chromaffin cells are Neuroendocrine cells found in the medulla of the Adrenal gland (suprarenal gland - located above the kidneys and in other ganglia Androgen is the generic term for any natural or synthetic compound usually a Steroid Hormone, that stimulates or controls the development and maintenance of masculine Testosterone is a Steroid hormone from the Androgen group In mammals testosterone is primarily secreted in the testes of males and the Ovaries Leydig cells, also known as interstitial cells of Leydig, are found adjacent to the Seminiferous tubules in the testicle. Anabolism is the set of Metabolic pathways that construct molecules from smaller units Muscle (from Latin musculus, diminutive of mus "mouse" is contractile tissue of the body and is derived from the Bone density (or bone mineral density) is a medical term referring to the amount of matter per cubic centimeter of Bones It is measured by a procedure called In biology and medicine virilization refers to the biological development of Sex differences, changes which make a Male body different from a Female body A sex organ, or primary sexual characteristic, as narrowly defined is any of the anatomical parts of the body which are involved in sexual reproduction and constitute In some Male Mammals the scrotum - also 'scrutum' or 'scrootum' - is a protuberance of Skin and Muscle containing the Testicles Underarm Hair (also called axillary hair or armpit hair) is the composition of Hair in the Underarm area

EstradiolSertoli cellsPrevent apoptosis of germ cells[12]
InhibinSertoli cells | Inhibit production of FSH

Ovary

These originate either from the ovarian follicle or the corpus luteum. Estradiol (17β-estradiol (also oestradiol) is a Sex hormone. A Sertoli cell (a kind of Sustentacular cell) is a 'nurse' cell of the testes which is part of a Seminiferous tubule. Inhibin is a peptide that is an inhibitor of FSH Synthesis and Secretion, and participates in the regulation of the Menstrual cycle A Sertoli cell (a kind of Sustentacular cell) is a 'nurse' cell of the testes which is part of a Seminiferous tubule. Follicle-stimulating hormone ( FSH) is a Hormone synthesized and secreted by Gonadotropes in the Anterior pituitary gland. "Ovaria" redirects here This is also a proposed section and a Synonym of Solanum. Ovarian follicle is the basic unit of female reproductive biology and is composed of a roughly spherical aggregations of cells found in the Ovary. The corpus luteum ( Latin for "yellow body" (plural corpora lutea) is a temporary Endocrine structure in mammals involved in production of

Secreted hormoneFrom cellsEffect
ProgesteroneGranulosa cells, theca cellsSupport pregnancy[13]:
  • Convert endometrium to secretory stage
  • Make cervical mucus permeable to sperm. Progesterone is a C-21 Steroid Hormone involved in the Female Menstrual cycle, Pregnancy (supports Gestation A granulosa cell is a Somatic cell found closely associated with the developing female Gamete (called an Oocyte or egg The theca folliculi comprise a layer of the Ovarian follicles They appear as the follicles become Tertiary follicles The theca are divided into two layers the Pregnancy ( Latin graviditas) is the carrying of one or more offspring known as a Fetus or Embryo, inside the Uterus of a Female The endometrium is the inner membrane of the Mammalian Uterus. The cervix (from Latin "neck" is the lower narrow portion of the Uterus where it joins with the top end of the Vagina.
  • Inhibit immune response, e. An immune system is a collection of mechanisms within an Organism that protects against Disease by identifying and killing Pathogens and Tumor g. , towards the human embryo
  • Decrease uterine smooth muscle contractility[13]
  • Inhibit lactation
  • Inhibit onset of labor. An embryo (from Greek:, plural, lit "that which grows" from en- "in" + bryein "to swell be full" is a multicellular Smooth muscle is a type of non- Striated muscle, found within the Tunica media layer of large and small Arteries and Veins, the bladder Lactation describes the secretion of Milk from the Mammary glands the process of providing that milk to the young and the period of time that a Mother Childbirth (also called labour, birth, partus or parturition) is the culmination of a Human Pregnancy or

Other:

Anti-inflammatory

AndrostenedioneTheca cellsSubstrate for estrogen
Estrogens (mainly estradiol)Granulosa cellsStructural:

Protein synthesis:

  • Increase hepatic production of binding proteins

Coagulation:

Fluid balance:

Gastrointestinal tract:

  • Reduce bowel motility
  • Increase cholesterol in bile

Melanin:

Cancer:

  • Support hormone-sensitive breast cancers [16] (Suppression of production in the body of estrogen is a treatment for these cancers. Epidermal growth factor or EGF is a Growth factor that plays an important role in the regulation of Cell growth, Proliferation, and A spasm is a sudden involuntary contraction of a Muscle, a group of muscles or a hollow organ, or a similarly sudden Contraction of an Orifice Smooth muscle is a type of non- Striated muscle, found within the Tunica media layer of large and small Arteries and Veins, the bladder A bronchus (plural bronchi, adjective bronchial) is a caliber of airway in the Respiratory tract that conducts air into the Lungs No Gas In vertebrates mucus is a slippery secretion produced by and covering Mucous membranes It is a viscous Colloid containing Antiseptic enzymes (such as Inflammation ( Latin, inflamatio, to set on fire is the complex biological response of vascular tissues to harmful stimuli such as Pathogens The gallbladder (or cholecyst sometimes gall bladder is a small organ whose function in the body is to store Bile and aid in the digestive process Blood is a specialized Bodily fluid that delivers necessary substances to the body's cells such as nutrients and oxygen—and transports Waste products Zinc (ˈzɪŋk from Zink is a Metallic Chemical element with the symbol Zn and Atomic number 30 Copper (ˈkɒpɚ is a Chemical element with the symbol Cu (cuprum and Atomic number 29 The cell is the structural and functional unit of all known living Organisms It is the smallest unit of an organism that is classified as living and is often called Oxygen (from the Greek roots ὀξύς (oxys (acid literally "sharp" from the taste of acids and -γενής (-genēs (producer literally begetteris the The thyroid is one of the largest Endocrine glands in the body Bones are rigid organs that form part of the Endoskeleton of Vertebrates They function to move support and protect the various organs of the body produce An osteoblast (from the Greek words for " Bone " and "germ" or embryonic is a mononucleate cell that is responsible for bone formation Resilience is the property of a material to absorb energy when it is deformed elastically and then upon unloading to have this energy recovered Bones are rigid organs that form part of the Endoskeleton of Vertebrates They function to move support and protect the various organs of the body produce The gingiva (sing and plur: gingiva) or gums, consists of the Mucosal tissue that lies over the Alveolar bone. A joint is the location at which two or more Bones make contact A tendon (or sinew) is a tough band of Fibrous connective tissue that usually connects Muscle to Bone and is capable of withstanding tension In Anatomy, the term ligament is used to denote three different types of structures Fibrous tissue that connects Bones to other bones The skin is the outer covering of living tissue of an animal (or plant Collagen is the main Protein of Connective tissue in Animals and the most abundant protein in Mammals making up about 50% of the whole-body protein Myelin is an electrically-insulating Dielectric Phospholipid layer that surrounds only the Axons of many Neurons It is an outgrowth Endometrial cancer refers to several types of malignancy which arise from the Endometrium, or lining of the Uterus. Androstenedione (also known as 4-androstenedione) is a 19- Carbon Steroid Hormone produced in the Adrenal glands and the Gonads The theca folliculi comprise a layer of the Ovarian follicles They appear as the follicles become Tertiary follicles The theca are divided into two layers the Estrogens (US otherwise oestrogens or œstrogens) are a group of Steroid compounds named for their importance in the Estrous cycle, Estrogens (US otherwise oestrogens or œstrogens) are a group of Steroid compounds named for their importance in the Estrous cycle, Estradiol (17β-estradiol (also oestradiol) is a Sex hormone. A granulosa cell is a Somatic cell found closely associated with the developing female Gamete (called an Oocyte or egg Secondary sex characteristics are traits that distinguish the two Sexes of a species but that are not directly part of the Reproductive system. Height is the measurement of vertical Distance, but has two meanings in common use Metabolism is the set of Chemical reactions that occur in living Organisms in order to maintain Life. Muscle (from Latin musculus, diminutive of mus "mouse" is contractile tissue of the body and is derived from the The endometrium is the inner membrane of the Mammalian Uterus. The uterus (from the Latin word for womb) is the major Female reproductive organ of most Mammals including Humans One end the The blood vessels are part of the Circulatory system and function to transport Blood throughout the body Bone resorption is the process by which Osteoclasts break down Bone and release the Minerals resulting in a transfer of calcium from bone fluid to the blood Proteins are large Organic compounds made of Amino acids arranged in a linear chain and joined together by Peptide bonds between the Carboxyl Coagulation is a complex process by which Blood forms Clots It is an important part of Hemostasis (the cessation of blood loss from a damaged vessel whereby Coagulation is a complex process by which Blood forms Clots It is an important part of Hemostasis (the cessation of blood loss from a damaged vessel whereby Thrombin (activated Factor II ') is a Coagulation protein that has many effects in the coagulation cascade. Factor VII (formerly known as proconvertin) is one of the central Proteins in the coagulation cascade. Factor IX (or Christmas factor) is one of the Serine proteases ( of the Coagulation system it belongs to peptidase family S1 Factor X, also known by the Eponym Stuart-Prower factor or as thrombokinase, is an Enzyme ( of the coagulation cascade. Antithrombin (AT is a small protein molecule that inactivates several enzymes of the Coagulation system Plasmin is an important Enzyme ( present in Blood that degrades many Blood plasma proteins most notable Fibrin clots The degradation Platelets, or Thrombocytes, are small cytoplasmic bodies derived from cells They circulate in the Blood of Mammals and are involved High-density lipoproteins ( HDL) is one of the 5 major groups of Lipoproteins ( Chylomicrons, VLDL, IDL, LDL, HDL (more properly known as, TAG or triacylglyceride) is Glyceride in which the Glycerol is Esterified with three Fatty acids It is the Height is the measurement of vertical Distance, but has two meanings in common use Low-density lipoprotein ( LDL) is a type of Lipoprotein that transports Cholesterol and Triglycerides from the Liver to peripheral Fats consist of a wide group of compounds that are generally soluble in organic solvents and largely insoluble in water Sodium (ˈsoʊdiəm is an element which has the symbol Na( Latin natrium, from Arabic natrun) atomic number 11 atomic mass 22 Growth hormone ( GH) is a Peptide hormone that stimulates growth and cell reproduction in humans and other animals Cortisol is a Corticosteroid Hormone produced by the Adrenal gland (in the Zona fasciculata of the Adrenal cortex) Sex hormone-binding globulin ( SHBG) is a Glycoprotein that binds to Sex hormones, specifically Testosterone and Estradiol. Bile or gall is a bitter yellow or green Alkaline fluid secreted by Hepatocytes from the Liver of most Vertebrates In many species Melanin is a class of compounds found in the Plant, Animal and Protista kingdoms, where it serves predominantly as a Pigment. Melanin is a class of compounds found in the Plant, Animal and Protista kingdoms, where it serves predominantly as a Pigment. Breast cancer is a Cancer that starts in the cells of the Breast in women and men )

Lung function:

  • Promote lung function by supporting alveoli[17]. An alveolus (plural alveoli, from Latin alveolus, "little cavity" is an anatomical structure that has the form of a hollow cavity
InhibinGranulosa cellsInhibit production of FSH from anterior pituitary

Placenta (when pregnant)

Secreted hormoneAbbreviationFrom cellsEffect
Progesterone (Primarily)Support pregnancy[13]:
  • Inhibit immune response, towards the fetus. Inhibin is a peptide that is an inhibitor of FSH Synthesis and Secretion, and participates in the regulation of the Menstrual cycle A granulosa cell is a Somatic cell found closely associated with the developing female Gamete (called an Oocyte or egg Follicle-stimulating hormone ( FSH) is a Hormone synthesized and secreted by Gonadotropes in the Anterior pituitary gland. The anterior pituitary (also called the adenohypophysis, from Greek adeno, "gland" hypo, "under" physis, "growth" The placenta is an Ephemeral organ present in placental Vertebrates, such as Eutherial Mammals and Sharks during Gestation Pregnancy ( Latin graviditas) is the carrying of one or more offspring known as a Fetus or Embryo, inside the Uterus of a Female Progesterone is a C-21 Steroid Hormone involved in the Female Menstrual cycle, Pregnancy (supports Gestation Pregnancy ( Latin graviditas) is the carrying of one or more offspring known as a Fetus or Embryo, inside the Uterus of a Female An immune system is a collection of mechanisms within an Organism that protects against Disease by identifying and killing Pathogens and Tumor A fetus (or foetus or fœtus) is a developing Mammal or other Viviparous Vertebrate, after the Embryonic stage and
  • Decrease uterine smooth muscle contractility[13]
  • Inhibit lactation
  • Inhibit onset of labor. Smooth muscle is a type of non- Striated muscle, found within the Tunica media layer of large and small Arteries and Veins, the bladder Lactation describes the secretion of Milk from the Mammary glands the process of providing that milk to the young and the period of time that a Mother Childbirth (also called labour, birth, partus or parturition) is the culmination of a Human Pregnancy or
  • Support fetal production of adrenal mineralo- and glucosteroids. A fetus (or foetus or fœtus) is a developing Mammal or other Viviparous Vertebrate, after the Embryonic stage and In Mammals the adrenal glands (also known as suprarenal glands) are the triangle-shaped Endocrine glands that sit on top of the Kidneys their

Other effects on mother similar to ovarian follicle-progesterone

Estrogens (mainly Estriol) (Also Primarily)Effects on mother similar to ovarian follicle estrogen
Human chorionic gonadotropinHCGSyncytiotrophoblastpromote maintenance of corpus luteum during beginning of pregnancy

Inhibit immune response, towards the human embryo. Estrogens (US otherwise oestrogens or œstrogens) are a group of Steroid compounds named for their importance in the Estrous cycle, Estriol (also oestriol) is one of the three main Estrogens produced by the human body Human chorionic gonadotropin ( hCG) is a Glycoprotein Hormone produced in Pregnancy that is made by the Embryo soon after conception Syncytiotrophoblasts are Multinucleated cells found in the Placenta of embryos The corpus luteum ( Latin for "yellow body" (plural corpora lutea) is a temporary Endocrine structure in mammals involved in production of Pregnancy ( Latin graviditas) is the carrying of one or more offspring known as a Fetus or Embryo, inside the Uterus of a Female An immune system is a collection of mechanisms within an Organism that protects against Disease by identifying and killing Pathogens and Tumor An embryo (from Greek:, plural, lit "that which grows" from en- "in" + bryein "to swell be full" is a multicellular

Human placental lactogenHPLSyncytiotrophoblastincrease production of insulin and IGF-1

increase insulin resistance and carbohydrate intolerance

InhibinFetal Trophoblastssuppress FSH

Uterus (when pregnant)

Secreted hormoneAbbreviationFrom cellsEffect
ProlactinPRLDecidual cellsmilk production in mammary glands
RelaxinDecidual cellsUnclear in humans

See also

External links

References

  1. ^ Collier, Judith. Syncytiotrophoblasts are Multinucleated cells found in the Placenta of embryos Insulin is a Hormone with intensive effects on both metabolism and several other body systems (eg vascular compliance Insulin-like growth factor 1 (IGF-1 that was once called somatomedin C is a Polypeptide Protein Hormone similar in Molecular structure Insulin resistance is the condition in which normal amounts of Insulin are inadequate to produce a normal Insulin response from Fat, Muscle Carbohydrates (from ' Hydrates of Carbon ' or saccharides ( Greek σάκχαρον meaning " Sugar " are the most Inhibin is a peptide that is an inhibitor of FSH Synthesis and Secretion, and participates in the regulation of the Menstrual cycle Trophoblasts (from Greek threphein: to feed and blastos: germinator are cells forming the outer layer of a Blastocyst, which provide nutrients Follicle-stimulating hormone ( FSH) is a Hormone synthesized and secreted by Gonadotropes in the Anterior pituitary gland. The uterus (from the Latin word for womb) is the major Female reproductive organ of most Mammals including Humans One end the Pregnancy ( Latin graviditas) is the carrying of one or more offspring known as a Fetus or Embryo, inside the Uterus of a Female Prolactin ( PRL) or Luteotropic hormone ( LTH) is a Peptide hormone primarily associated with Lactation. Before the fertilized Ovum reaches the Uterus, the Mucous membrane of the body of the uterus undergoes important changes and is then known as the Decidua Mammary glands are the organs that in Mammals produce Milk for the sustenance of the young For the Miles Davis album see Relaxin' with the Miles Davis Quintet. Before the fertilized Ovum reaches the Uterus, the Mucous membrane of the body of the uterus undergoes important changes and is then known as the Decidua A releasing hormone or releasing factor is a hormone whose main purpose is to control the release of another hormone Neuroendocrinology is the study of the interactions between the Nervous system and the Endocrine system. The nervous system is a Network of specialized cells that communicate information about an animal's surroundings and itself Endocrine disruptors (sometimes also referred to as hormonally active agents) are Exogenous substances that act like Hormones in the Endocrine system Human anatomy, which with physiology and biochemistry is a complementary basic medical science is primarily the scientific study of the morphology of the adult Human body et. al (2006). Oxford Handbook of Clinical Specialties 7th edn. . Oxford, 350 -351. Oxford is currently bidding for the 2010 Wikimania Conference Oxford () is a city, and the County town of Oxfordshire, ISBN 0-19-853085-4.  
  2. ^ University of Virginia - HISTOLOGY OF THE ENDOCRINE GLANDS
  3. ^ Kasper et al. (2005). Harrison's Principles of Internal Medicine. McGraw Hill, 2074. The McGraw-Hill Companies Inc, ( is a Publicly traded corporation headquartered in Rockefeller Center in New York City. ISBN 0-07-139140-1.  
  4. ^ Bhowmick NA, Chytil A, Neilson EG, Moses HL (2004). "TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. ". Science Feb 6 303(5659): 848–51. doi:10.1126/science.1090922. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document.  
  5. ^ Kosfeld M et al. (2005) Oxytocin increases trust in humans. Nature 435:673-676. Nature is a prominent Scientific journal, first published on 4 November 1869 PDF PMID 15931222
  6. ^ Scientific American Mind, "Rhythm and Blues"; June/July 2007; Scientific American Mind; by Ulrich Kraft
  7. ^ a b c Kaushansky K. Lineage-specific hematopoietic growth factors. N Engl J Med 2006;354:2034-45. The New England Journal of Medicine ( N Engl J Med or NEJM) is an English-language Peer-reviewed Medical journal published PMID 16687716.
  8. ^ The adipose tissue as a source of vasoactive factors. Frühbeck G. (Curr Med Chem Cardiovasc Hematol Agents. 2004 Jul;2(3):197-208. )
  9. ^ http://www.vivo.colostate.edu/hbooks/pathphys/endocrine/otherendo/somatostatin.html Colorado State University - Biomedical Hypertextbooks - Somatostatin
  10. ^ Diabetes-related changes in contractile responses of stomach fundus to endothelin-1 in streptozotocin-induced diabetic rats Journal of Smooth Muscle Research Vol. 41 (2005) , No. 1 35-47. Kazuki Endo1), Takayuki Matsumoto1), Tsuneo Kobayashi1), Yutaka Kasuya1) and Katsuo Kamata1)
  11. ^ a b Physiology at MCG 5/5ch4/s5ch4_17
  12. ^ Pentikäinen V, Erkkilä K, Suomalainen L, Parvinen M, Dunkel L. The Medical College of Georgia, also known as MCG, is a public medical Research university located in downtown Augusta Georgia. Estradiol Acts as a Germ Cell Survival Factor in the Human Testis in vitro. The Journal of Clinical Endocrinology & Metabolism 2006;85:2057-67 PMID 10843196
  13. ^ a b c d Placental Hormones
  14. ^ Physiology at MCG 5/5ch9/s5ch9_13
  15. ^ Hould F, Fried G, Fazekas A, Tremblay S, Mersereau W (1988). The Medical College of Georgia, also known as MCG, is a public medical Research university located in downtown Augusta Georgia. "Progesterone receptors regulate gallbladder motility". J Surg Res 45 (6): 505–12. doi:10.1016/0022-4804(88)90137-0. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 3184927.  
  16. ^ Hormonal Therapy
  17. ^ Massaro D, Massaro GD (2004). "Estrogen regulates pulmonary alveolar formation, loss, and regeneration in mice". American Journal of Physiology. Lung Cellular and Molecular Physiology 287 (6): L1154–9. doi:10.1152/ajplung.00228.2004. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 15298854 doi= 10. 1152/ajplung. 00228. 2004.  

Dictionary

endocrine system

-noun

  1. (physiology) A control system of ductless glands that secrete hormones which circulate via the bloodstream to affect cells within specific organs.
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