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Sir Edwin Southern

Born 1938
United Kingdom
Nationality British
Fields Biochemistry
Institutions University of Oxford, University of Edinburgh
Known for Inventor of the Southern blot
Notable awards Gairdner Foundation International Award (1990),
Albert Lasker Award for Clinical Medical Research (2005)

Professor Sir Edwin Mellor Southern, FRS (born 1938) [1] is a 2005 Lasker Award-winning molecular biologist. The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom, the UK or Britain,is a Sovereign state located The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom, the UK or Britain,is a Sovereign state located Biochemistry is the study of the chemical processes in living Organisms It deals with the Structure and function of cellular components such as The University of Oxford (informally "Oxford University" or simply "Oxford" located in the city of Oxford, Oxfordshire, England is the The University of Edinburgh (Oilthigh Dhùn Èideann founded in 1582 is a renowned centre for teaching and research in Edinburgh, Scotland, UK. A Southern blot is a method routinely used in Molecular biology to check for the presence of a DNA sequence in a DNA sample The Gairdner Foundation International Award is given annually at a special dinner to three to six people for outstanding discoveries or contributions to medical science The Lasker~DeBakey Clinical Medical Research Award is awarded by the Lasker Foundation for the understanding diagnosis prevention treatment and cure of disease The Royal Society of London for the Improvement of Natural Knowledge, known simply as The Royal Society, is a Learned society for science that was founded in 1660 Year 1938 ( MCMXXXVIII) was a Common year starting on Saturday (link will display the full calendar of the Gregorian calendar. Year 2005 ( MMV) was a Common year starting on Saturday (link displays full calendar of the Gregorian calendar. The Albert Lasker Medical Research Awards have been awarded annually since 1946 to living persons who have made major contributions to Medical science. Molecular biology is the study of Biology at a molecular level His award is for the invention of the Southern blot, now a common laboratory procedure, when he was working at the University of Edinburgh. A Southern blot is a method routinely used in Molecular biology to check for the presence of a DNA sequence in a DNA sample The University of Edinburgh (Oilthigh Dhùn Èideann founded in 1582 is a renowned centre for teaching and research in Edinburgh, Scotland, UK. Professor Southern is Professor of Biochemistry (Emeritus) at the University of Oxford and a fellow of Trinity College. The University of Oxford (informally "Oxford University" or simply "Oxford" located in the city of Oxford, Oxfordshire, England is the The College of the Holy and Undivided Trinity in the University of Oxford of the foundation of Sir Thomas Pope (Knight, or Trinity College for short is one of the He was made a Knight Bachelor in the June 2003 Birthday Honours for services to the development of DNA Microarray Technologies. The rank of Knight Bachelor is a part of the British honours system.

Southern is the Founder, Chairman and Chief Scientific Officer of Oxford Gene Technology. He is also the founder and chairman of a Scottish charity, The Kirkhouse Trust, which aims to promote education and research in the Natural Sciences, particularly the biological and medical sciences. In addition the Edina Trust was founded to promote science in schools. These charities are financed using royalty income from licensing microarray technology.

Contents

Southern blot

The Southern blot is used for DNA analysis and was routinely used for genetic fingerprinting and paternity testing prior to the development of microsatellite markers for this purpose. Deoxyribonucleic acid ( DNA) is a Nucleic acid that contains the genetic instructions used in the development and functioning of all known A maternity or paternity identification test is conducted to establish whether a person is the biological Parent of another person The procedure is also frequently used to determine the number of copies of a gene in the genome. The concepts of the Southern blot were used in the development and creation of the modern microarray slide, which is a promising experimental tool. The northern blot is a similar procedure for RNA, playing off the Southern name. The northern blot is a technique used in Molecular biology research to study Gene expression. Ribonucleic acid ( RNA) is a Nucleic acid that consists of a long chain of Nucleotide units The western blot is a further pun on the Southern blot, but is an important research tool in protein detection. The western blot (alternatively immunoblot) is an Analytical technique used to detect specific Proteins in a given sample of tissue homogenate or

Awards

In 1990 Southern was one of the winners of the Gairdner Foundation International Award. The Gairdner Foundation International Award is given annually at a special dinner to three to six people for outstanding discoveries or contributions to medical science [2] In 1998 he was awarded the Royal Medal of the Royal Society of London. The Royal Medals of the Royal Society of London, also as The Queen's Medals were established by King George IV. The Royal Society of London for the Improvement of Natural Knowledge, known simply as The Royal Society, is a Learned society for science that was founded in 1660 [3] In 2005 he was awarded the prestigious Albert Lasker Award for Clinical Medical Research,[1][4] jointly with Alec Jeffreys of the University of Leicester for his invention of the Southern blot. The Lasker~DeBakey Clinical Medical Research Award is awarded by the Lasker Foundation for the understanding diagnosis prevention treatment and cure of disease Sir Alec John Jeffreys, FRS (born 9 January 1950 at Oxford in Oxfordshire) is a British Geneticist, who developed techniques The University of Leicester is a research led university based in Leicester, England, with approximately 19000 registered students - about 12000 of them full-time [5] In 2005 he was also awarded the Association of Biomolecular Resource Facilities Award for outstanding contributions to Biomolecular Technologies. The Association of Biomolecular Resource Facilities (ABRF is dedicated to advancing core and research biotechnology laboratories through research communication and education [6]

References

  1. ^ a b Southern, Edwin (October 2005). "Tools for genomics" (). Nature Medicine: Commentary 11 (10). Nature Medicine is an Academic journal publishing research articles reviews news and commentaries in the biomedical area including both basic research and  
  2. ^ List of winners. The Gairdner Foundation. Retrieved on 19 December 2007.
  3. ^ Royal recent winners. The Royal Society. The Royal Society of London for the Improvement of Natural Knowledge, known simply as The Royal Society, is a Learned society for science that was founded in 1660 Retrieved on 20 December 2007.
  4. ^ 2005 Albert Lasker Award - Acceptance remarks by Edwin Southern. Lasker Foundation. Retrieved on 19 December 2007.
  5. ^ 2005 Albert Lasker Award for Clinical Medical Research. Lasker Foundation. Retrieved on 19 December 2007.
  6. ^ ABRF Award. Association of Biomolecular Resource Facilities. The Association of Biomolecular Resource Facilities (ABRF is dedicated to advancing core and research biotechnology laboratories through research communication and education Retrieved on 19 December 2007.

External links

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