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Dirlotapide
Systematic (IUPAC) name
1-Methyl-N-[(1S)-2-(methyl-(phenylmethyl)amino)-2-oxo-1-phenylethyl]-5-[ [oxo-[2-[4-(trifluoromethyl)phenyl]phenyl]methyl]amino]-2-indolecarboxamide
Identifiers
CAS number 481658-94-0
ATC code  ?
PubChem  ?
Chemical data
Formula C40H33F3N4O3 
Mol. mass 674. IUPAC Nomenclature is a system of naming Chemical compounds and of describing the science of Chemistry in general CAS registry numbers are unique numerical identifiers for Chemical compounds Polymers biological sequences mixtures and Alloys They are also referred to The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs It is controlled by the WHO Collaborating Centre for Drug PubChem is a Database of chemical Molecules The system is maintained by the National Center for Biotechnology Information (NCBI a component A chemical formula is a way of expressing information about the Atoms that constitute a particular Chemical compound, and how the relationship between those atoms changes Carbon (kɑɹbən is a Chemical element with the symbol C and its Atomic number is 6 Hydrogen (ˈhaɪdrədʒən is the Chemical element with Atomic number 1 Fluorine, fluorum meaning "to flow" is the Chemical element with the symbol F and Atomic number 9 Nitrogen (ˈnaɪtɹəʤɪn is a Chemical element that has the symbol N and Atomic number 7 and Atomic weight 14 Oxygen (from the Greek roots ὀξύς (oxys (acid literally "sharp" from the taste of acids and -γενής (-genēs (producer literally begetteris the The molecular mass (abbreviated m of a substance, more commonly referred to as molecular weight and abbreviated as MW, is the Mass of one 71 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Dirlotapide is a drug used to treat obesity in dogs. In Pharmacology, bioavailability is used to describe the fraction of an administered Dose of unchanged drug that reaches the Systemic circulation, one of Drug metabolism is the Metabolism of drugs, their Biochemical modification or degradation usually through specialized enzymatic systems The biological half-life of a substance is the time it takes for a substance (drug radioactive nuclide or other to lose half of its pharmacologic physiologic or radiologic activity Excretion is the process of eliminating waste products of Metabolism and other non-useful materials The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical if it is used as directed by the mother during The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction In Pharmacology and Toxicology, a route It is manufactured by Pfizer and marketed as Slentrol. Pfizer Incorporated ( is a major Pharmaceutical company, which ranks number one in the world in sales

It works as a selective microsomal triglyceride transfer protein inhibitor. In Cell biology, a microsome is a small Vesicle that is derived from fragmented Smooth endoplasmic reticulum (SER produced when tissues such as liver are (more properly known as, TAG or triacylglyceride) is Glyceride in which the Glycerol is Esterified with three Fatty acids It is the This blocks the assembly and release of lipoproteins into the bloodstream, thereby reducing fat absorption. A lipoprotein is a biochemical assembly that contains both Proteins and Lipids The lipids or their derivatives may be covalently or non-covalently bound It also elicits a satiety signal from lipid-filled cells lining the intestine. Hunger is a feeling experienced usually followed by a desire to Eat.

It is supplied as an oral solution. It is not intended for use in humans or cats or parrots.

On January 5 2007, the FDA approved Slentrol, the first time the FDA has approved a drug for obese dogs. Events 1477 - Battle of Nancy: Charles the Bold is killed and Burgundy becomes part of France. [1]

References

  1. ^ FDA approves 1st drug for obese dogs. Yahoo. Retrieved on 2007-01-06. Year 2007 ( MMVII) was a Common year starting on Monday of the Gregorian calendar in the 21st century. Events 1066 - Harold Godwinson is crowned King of England. 1205 - Philip of Swabia becomes King

External links



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