Skeletal formulas and substituent numbering schemes of Dioxin isomers

Not to be confused with dioxane or digoxin. The skeletal formula of an Organic compound is a shorthand representation of its molecular structure. In Organic chemistry, a substituent is an atom or group of atoms substituted in place of a Hydrogen atom on the Parent chain of a Hydrocarbon Digoxin ( INN) (dɨˈdʒɒksɨn also known as Digitalis, is a purified Cardiac glycoside extracted from the Foxglove plant Digitalis

Dioxin is a heterocyclic organic compound with the chemical formula C₄H₄O₂. An organic compound is any member of a large class of Chemical compounds whose Molecules contain Carbon. A chemical compound is a substance consisting of two or more different elements chemically bonded together in a fixed proportion by Mass. A chemical formula is a way of expressing information about the Atoms that constitute a particular Chemical compound, and how the relationship between those atoms changes There are two isomers, 1,2-dioxin (or o-dioxin) and 1,4-dioxin (or p-dioxin). This article is about the chemical concept For "isomerism" of atomic nuclei see Nuclear isomer. Their chemical structures are shown at right. Chemical structure refers to Molecular geometry, Electronic structure and Crystal structure. The ortho isomer 1,2-dioxin is very unstable due to its peroxide-like characteristics.

The known properties of 1,4-dioxin are listed in the infobox to the right.

1,4-Dioxin
IUPAC name	1,4-dioxin
Other names	p-dioxin, dioxin
Identifiers
CAS number	[290-67-5]
Properties
Molecular formula	C4H4O2
Molar mass	84. IUPAC Nomenclature is a system of naming Chemical compounds and of describing the science of Chemistry in general CAS registry numbers are unique numerical identifiers for Chemical compounds Polymers biological sequences mixtures and Alloys They are also referred to A chemical formula is a way of expressing information about the Atoms that constitute a particular Chemical compound, and how the relationship between those atoms changes Molar mass, symbol M, is the Mass of one mole of a substance ( Chemical element or Chemical compound) 07 g/mol
Appearance	Colorless liquid
Boiling point	75°C (348°K)
Hazards
EU classification	Toxic (T)
Main hazards	highly flammable
Related compounds
Related compounds	dibenzodioxin
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

1,4-dioxin can be prepared by cycloaddition, namely by the Diels-Alder reaction. The boiling point of a liquid is the temperature at which the Vapor pressure of the liquid equals the environmental pressure surrounding the liquid Council Directive 67/548/EEC of 27 June 1967 on the approximation of laws regulations and administrative provisions relating to the classification packaging and labelling Occupational safety and health is a cross-disciplinary area concerned with protecting the Safety, Health and welfare of people engaged in Dibenzodioxin, C12H8O2 is an organic heterocyclic compound in which two benzene rings are attached to a Dioxin ring In Chemistry, the standard state of a material is its state at 1 bar (100 Kilopascals exactly A cycloaddition is a Pericyclic Chemical reaction, in which two π bonds are lost and two σ bonds are gained the resulting reaction is a The Diels-Alder reaction is an Organic chemical reaction (specifically a Cycloaddition) between a conjugated Diene and a substituted Alkene, ^[1]

Other meanings (See other articles)

The skeletal formula and substituent numbering scheme of dibenzo-p-dioxin, the parent compound of PCDDs

The word dioxin can also in a general way refer to compounds whose molecules have a dioxin core skeletal structure with substituent molecular groups attached to it. The skeletal formula of an Organic compound is a shorthand representation of its molecular structure. In Organic chemistry, a substituent is an atom or group of atoms substituted in place of a Hydrogen atom on the Parent chain of a Hydrocarbon Dibenzodioxin, C12H8O2 is an organic heterocyclic compound in which two benzene rings are attached to a Dioxin ring Polychlorinated dibenzodioxins ( PCDD s or simply dioxins, are a group of Halogenated Organic compounds which are significant because they act In Organic chemistry, a substituent is an atom or group of atoms substituted in place of a Hydrogen atom on the Parent chain of a Hydrocarbon For example, dibenzo-p-dioxin is a compound whose structure consists of two benzo- groups fused onto a p-dioxin ring as shown below (see also Dibenzodioxin). Not to be confused with Dioxane or Digoxin. Dioxin is a heterocyclic, organic, antiaromatic compound Dibenzodioxin, C12H8O2 is an organic heterocyclic compound in which two benzene rings are attached to a Dioxin ring

Because of their extreme importance as environmental pollutants, current scientific literature uses the name dioxins commonly for simplification to denote the chlorinated derivatives of dibenzo-p-dioxin, more precisely the polychlorinated dibenzodioxins (PCDDs). Polychlorinated dibenzodioxins ( PCDD s or simply dioxins, are a group of Halogenated Organic compounds which are significant because they act The polychlorinated dibenzodioxins, which can also be classified in the family of halogenated organic compounds, have been shown to bioaccumulate in humans and wildlife due to their lipophilic properties, and are known teratogens, mutagens, and carcinogens. Polychlorinated dibenzodioxins ( PCDD s or simply dioxins, are a group of Halogenated Organic compounds which are significant because they act Halocarbon compounds are Chemicals in which one or more Carbon Atoms are linked by Covalent bonds with one or more Halogen Atoms Bioaccumulation occurs when an organism absorbs a toxic substance at a rate greater than that at ftudruinsubstance is lost Wildlife includes all non-domesticated plants animals and other organisms Lipophilicity, fat-liking, refers to the ability of a Chemical compound to dissolve in fats oils lipids and non-polar solvents such as Hexane or Teratology stems from the Greek ( Genitive) meaning monster, or marvel and, meaning word, speech. In Biology, a mutagen ( Latin, literally origin of change) is a physical or chemical agent that changes the genetic information (usually DNA) The term carcinogen refers to any substance Radionuclide or radiation that is an agent directly involved in the promotion of Cancer or in the fatation of its propagation References under the main article on polychlorinated dibenzodioxins. Polychlorinated dibenzodioxins ( PCDD s or simply dioxins, are a group of Halogenated Organic compounds which are significant because they act

Additionally, sometimes with dioxins a similar, but unrelated compound type the polychlorinated dibenzofurans of like importance are also implied. Dibenzofuran is a Heterocyclic Organic compound with the Chemical structure shown at right

Toxicity

Some dioxin derivatives are known to increase the likelihood of cancer (See above under Other meanings). Cancer (medical term Malignant Neoplasm) is a class of Diseases in which a group of cells display uncontrolled Scientists are working to establish their exact toxicity. Toxicity is the degree to which a substance is able to damage an exposed organism The job is made difficult because we are not dealing with pure chemicals, but a mixture, and toxicity depends on the particular molecular arrangement of the compound, that of the highest toxicity is the 2,3,7,8-tetrachloro-para-dibenzo dioxin (pictured here as well). When people say dioxins, they often refer to these chlorinated derivatives, not the compound described in this article. These cases are discussed in detail in the article on Polychlorinated dibenzodioxin or PCDD but the toxicity of even some of these is disputed. Polychlorinated dibenzodioxins ( PCDD s or simply dioxins, are a group of Halogenated Organic compounds which are significant because they act The Vietnamese Veterans case, the Seveso case, and Lushchenko's chloracne case and more are all discussed in that article. Chloracne is an acne -like eruption of Blackheads Cysts and Pustules associated with over-exposure to certain Halogenated Aromatic Another group of compounds of similar toxicity to that of the PCDD's are the polychlorinated dibenzofurans, their toxicity is also discussed with Dioxin derivatives, sometimes calling them all erroneously dioxins. Dibenzofuran is a Heterocyclic Organic compound with the Chemical structure shown at right

References