Desoxycorticosterone
Systematic (IUPAC) name
?
Identifiers
CAS number	64-85-7
ATC code	H02AA03
PubChem	6166
Chemical data
Formula	C21H30O4
Mol. mass	330. IUPAC Nomenclature is a system of naming Chemical compounds and of describing the science of Chemistry in general CAS registry numbers are unique numerical identifiers for Chemical compounds Polymers biological sequences mixtures and Alloys They are also referred to The Anatomical Therapeutic Chemical Classification System is used for the classification of drugs It is controlled by the WHO Collaborating Centre for Drug A section of the Anatomical Therapeutic Chemical Classification System. PubChem is a Database of chemical Molecules The system is maintained by the National Center for Biotechnology Information (NCBI a component A chemical formula is a way of expressing information about the Atoms that constitute a particular Chemical compound, and how the relationship between those atoms changes Carbon (kɑɹbən is a Chemical element with the symbol C and its Atomic number is 6 Hydrogen (ˈhaɪdrədʒən is the Chemical element with Atomic number 1 Oxygen (from the Greek roots ὀξύς (oxys (acid literally "sharp" from the taste of acids and -γενής (-genēs (producer literally begetteris the The molecular mass (abbreviated m of a substance, more commonly referred to as molecular weight and abbreviated as MW, is the Mass of one 461
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Desoxycorticosterone (11-deoxycorticosterone) is a mineralocorticoid secreted from Zona reticularis and Zona fasciculata of the adrenal gland. In Pharmacology, bioavailability is used to describe the fraction of an administered Dose of unchanged drug that reaches the Systemic circulation, one of Drug metabolism is the Metabolism of drugs, their Biochemical modification or degradation usually through specialized enzymatic systems The biological half-life of a substance is the time it takes for a substance (drug radioactive nuclide or other to lose half of its pharmacologic physiologic or radiologic activity Excretion is the process of eliminating waste products of Metabolism and other non-useful materials The pregnancy category of a pharmaceutical agent is an assessment of the risk of fetal injury due to the pharmaceutical if it is used as directed by the mother during The regulation of therapeutic goods, that is drugs and therapeutic devices, varies by jurisdiction In Pharmacology and Toxicology, a route Mineralocorticoids are a class of Steroid hormones characterised by their similarity to Aldosterone and their influence on salt and water balance The zona reticularis is the innermost layer of the Adrenal cortex, lying deep to the Zona fasciculata and superficial to the Adrenal medulla. Cells of the zona fasciculata sit directly beneath the Zona glomerulosa and are organized in bundles (or Fascicles) In Mammals the adrenal glands (also known as suprarenal glands) are the triangle-shaped Endocrine glands that sit on top of the Kidneys their In the cytosol of the mitochondrion, pregnenolone is converted to either androgens or 11-deoxycorticosterone and 11-deoxycortisol by enzymes of the endoplasmic reticulum. The cytosol or intracellular fluid (or cytoplasmic matrix) is the liquid found inside cells. In Cell biology, a mitochondrion (plural mitochondria) is a membrane-enclosed Organelle found in most eukaryotic cells. Pregnenolone is a Steroid hormone involved in the Steroidogenesis of Progesterone, Mineralocorticoids, Glucocorticoids, Androgens The endoplasmic reticulum (Greek endo = "within" (prefix plásma = "formed entity" Latin reticulum = "little net" or ER, is an Organelle Then, 11-deoxycorticosterone, along with 11-deoxycortisol, re-enters the mitochondrion, where the enzymes are located for tissue-specific conversion to mineralocorticoids or glucocorticoids, respectively.

Desoxycorticosterone is commonly found in two forms: the acetate salt (desoxycorticosterone acetate, or DOCA) and the pivalate salt (desoxycorticosterone pivalate). An acetate, or ethanoate, is either a salt or Ester of Acetic acid. Salt is a Dietary mineral composed primarily of Sodium chloride that is essential for Animal life but toxic to most land plants Pivalic acid (or neopentanoic acid) is a Carboxylic acid with a molecular formula of C5H10O2 Both forms are given as intramuscular injections as replacement therapy for Addison's disease. An injection is an infusion method of putting Liquid into the Body, usually with a hollow needle and a Syringe which is pierced through Addison's disease (also known as chronic Adrenal insufficiency, '''hypocortisolism''' or '''hypocorticism) is a rare Endocrine disorder This disease is marked by insufficient adrenal function, including low mineralocorticoid levels. In Mammals the adrenal glands (also known as suprarenal glands) are the triangle-shaped Endocrine glands that sit on top of the Kidneys their

Desoxycorticosterone pivalate is sold for veterinary use by Novartis under the brand name Percoten. Veterinary medicine the application of medical, diagnostic, and therapeutic principles to companion, domestic, exotic, wildlife Novartis International AG is a multinational Pharmaceutical company based in Basel Switzerland that manufactures drugs such as Clozapine

References

http://web.indstate.edu/thcme/mwking/steroid-hormones.html

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