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DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
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| Identifiers | ||
| Symbol(s) | DDX31; FLJ13633; FLJ14578; FLJ23349; helicain A; helicain B; helicain C | |
| External IDs | MGI: 2682639 HomoloGene: 6389 | |
| RNA expression pattern | ||
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| Orthologs | ||
| Human | Mouse | |
| Entrez | 64794 | 227674 |
| Ensembl | ENSG00000125485 | n/a |
| Uniprot | Q9H8H2 | n/a |
| Refseq | NM_022779 (mRNA) NP_073616 (protein) |
NM_001033294 (mRNA) NP_001028466 (protein) |
| Location | Chr 9: 134.46 - 134.54 Mb | n/a |
| Pubmed search | [1] | [2] |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31, also known as DDX31, is a human gene. The Human Genome Organisation (HUGO is an organization involved in the Human Genome Project, a project about mapping the human genome The Mouse Genome Informatics (MGI website is run by The Jackson Laboratory. HomoloGene, a tool of the National Center for Biotechnology Information (NCBI is a system for automated detection of homologs (similarity attributable to descent The Entrez Global Query Cross-Database Search System is a powerful Federated search engine or Web portal that allows users to search many discrete Health sciences Ensembl is a joint scientific project between the European Bioinformatics Institute and the Wellcome Trust Sanger Institute, which was launched in 1999 in response to the imminent UniProt is the uni versal prot ein resource a central repository of Protein data created by combining Swiss-Prot, TrEMBL PubMed is a free search engine for accessing the MEDLINE database of citations and abstracts of biomedical research articles History See also History of genetics The existence of genes was first suggested by Gregor Mendel (1822-1884 who in the 1860s studied inheritance [1]
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants. [1]
References
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. ". Gene 138 (1-2): 171–4. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. ". Gene 200 (1-2): 149–56. PMID 9373149.
- Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus. ". Mol. Biol. Cell 13 (11): 4100–9. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 12429849.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ". Proc. Natl. Acad. Sci. U. S. A. 99 (26): 16899–903. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 12477932.
- Abdelhaleem M, Maltais L, Wain H (2004). "The human DDX and DHX gene families of putative RNA helicases. ". Genomics 81 (6): 618–22. PMID 12782131.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs. ". Nat. Genet. 36 (1): 40–5. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 14702039.
- Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9. ". Nature 429 (6990): 369–74. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 15164053.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ". Genome Res. 14 (10B): 2121–7. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 15489334.
- Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics. ". Nature 433 (7021): 77–83. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 15635413.
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