D-octopine dehydrogenase

In enzymology, a D-octopine dehydrogenase (EC 1.5.1.11) is an enzyme that catalyzes the chemical reaction

N₂-(D-1-carboxyethyl)-L-arginine + NAD⁺ + H₂O $\rightleftharpoons$ L-arginine + pyruvate + NADH + H⁺

The 3 substrates of this enzyme are N2-(D-1-carboxyethyl)-L-arginine, NAD⁺, and H₂O, whereas its 4 products are L-arginine, pyruvate, NADH, and H⁺. Enzymes are Biomolecules that catalyze ( ie increase the rates of Chemical reactions Almost all enzymes are Proteins This article is about the Enzyme Commission codes For the European Commission system for coding chemicals see EC-No. Enzymes are Biomolecules that catalyze ( ie increase the rates of Chemical reactions Almost all enzymes are Proteins Catalysis is the process in which the rate of a Chemical reaction is increased by means of a Chemical substance known as a catalyst A chemical reaction is a process that always results in the interconversion of Chemical substances The substance or substances initially involved in a chemical reaction are called Nicotinamide adenine dinucleotide, abbreviated NAD+, is a Coenzyme found in all living cells The compound is a dinucleotide since it consists Water is a common Chemical substance that is essential for the survival of all known forms of Life. A product is a substance that forms as a result of a Biological - or Chemical reaction. Arginine (abbreviated as Arg or R) is an α- Amino acid. The L-form is one of the 20 most common natural amino acids Pyruvic acid (CH3COCO2H is an alpha-keto acid. The Carboxylate Anion of pyruvic acid is known as pyruvate. Nicotinamide adenine dinucleotide, abbreviated NAD+, is a Coenzyme found in all living cells The compound is a dinucleotide since it consists Hydrogen ion is recommended by IUPAC as a general term for all Ions of Hydrogen and its Isotopes Depending on the Charge of the ion

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. In Biochemistry, an oxidoreductase is an Enzyme that catalyzes the transfer of Electrons from one molecule (the reductant, also called the hydrogen The systematic name of this enzyme class is N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming). Other names in common use include D-octopine synthase, octopine dehydrogenase, octopine:NAD+ oxidoreductase, ODH, 2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase, and (L-arginine-forming). This enzyme participates in arginine and proline metabolism.

References

IUBMB entry for 1.5.1.11
BRENDA references for 1.5.1.11 (Recommended. )
PubMed references for 1.5.1.11
PubMed Central references for 1.5.1.11
Google Scholar references for 1.5.1.11
Kemp JD, Hack E, Sutton DW and El-Wakil M (1979). "Unusual amino acids and their relationship to tumorigenesis". Proc. Int. Conf. Plant Pathol. Bact. 4th: 183–188.
van Thoai N, Huc C, Pho DB, Olomucki A (1969). "[Octopine dehydrogenase. Purification and catalytic properties]". Biochim. Biophys. Acta. 191: 46–57. PMID 4310628.

External links

The CAS registry number for this enzyme class is 37256-27-2. CAS registry numbers are unique numerical identifiers for Chemical compounds Polymers biological sequences mixtures and Alloys They are also referred to

IUBMB entry for 1.5.1.11

KEGG entry for 1.5.1.11

BRENDA entry for 1.5.1.11

NiceZyme view of 1.5.1.11

EC2PDB: PDB structures for 1.5.1.11

PRIAM entry for 1.5.1.11

PUMA2 entry for 1.5.1.11

IntEnz: Integrated Enzyme entry for 1.5.1.11

MetaCyc entry for 1.5.1.11

Atomic-resolution structures of enzymes belonging to this class

Gene Ontology (GO) codes

EGO entry for GO code 0047830: D-octopine dehydrogenase

AMIGO entry for GO code 0047830: D-octopine dehydrogenase

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