CofC may refer to:
- Church of Christ, non-denominational Christian church influenced by the Restoration Movement
- College of Charleston, public university located in Charleston, South Carolina
COFC may refer to "Container on Flatcar," a form of intermodal freight transport. The College of Charleston (C of C is a public, Sea-grant, and Space-grant university located in historic downtown Charleston South Carolina A flatcar (also flat car) is a piece of Railroad rolling stock that consists of an open flat deck on four or six wheels or a pair of trucks (US or Intermodal freight transport involves the transportation of freight in a container or Vehicle, using multiple modes of Transportation (
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