The Cl-formate exchanger is a transport protein present in the kidney[1], where it functions in the renal chloride reabsorption. The kidneys are complicated organs that have numerous biological roles Renal reabsorption of chloride ( Cl-) is a part of Renal physiology, in order not to lose too much chloride in the Urine. It is also present in vascular smooth muscle and cardiac muscle [2]. Vascular smooth muscle refers to the particular type of Smooth muscle found within and composing the majority of the wall of Blood vessels Vascular smooth muscle The cardiac muscle is a type of involuntary striated Muscle found in the walls of the Heart.
The true molecular nature of the protein is unknown[3].
References
- ^ Chloride/Formate Exchange with Formic Acid Recycling: A Mechanism of Active Chloride Transport across Epithelial Membranes Lawrence P. Karniski and Peter S. Aronson
- ^ [Presence of chloride-formate exchange in vascular smooth muscle and cardiac cells M Soleimani and RL Howard. Department of Medicine, Indiana University School of Medicine, Indianapolis 46202-5116.
- ^ renal proximal tubule cells Identification of a chloride-formate ...