Chinese Hamster Ovary cells (CHO cells) are a cell line derived from Chinese Hamster ovary cells. Cell culture is the process by which prokaryotic, or eukaryotic cells are grown under controlled conditions The Chinese Hamster is a species of Hamster, scientific names Cricetulus griseus, which originates in the Deserts of northern China and Mongolia "Ovaria" redirects here This is also a proposed section and a Synonym of Solanum. They are often used in biological and medical research. Foundations of modern biology There are five unifying principles Medicine is the art and science of healing It encompasses a range of Health care practices evolved to maintain and restore Human Health by the They were introduced in the 1960s and are used in a cultured monolayer in culture flasks. The 1960s decade refers to the years from the beginning of 1960 to the end of 1969 A microbiological culture, AKA microbial culture, is a method of multiplying microbial organisms by letting them reproduce in predetermined culture media under controlled laboratory They require the amino acid proline in their culture medium; this property makes them ideal for genetics research. In Chemistry, an amino acid is a Molecule containing both Amine and Carboxyl Functional groups In Biochemistry, this Proline (abbreviated as Pro or P) is an α- Amino acid, one of the twenty DNA -encoded amino acids Genetics (from Ancient Greek grc-Latn genetikos, “genitive” and that from grc-Latn genesis, “origin” a discipline of Biology, is CHO cells are used in studies of genetics, toxicity screening, nutrition and gene expression particularly expression of recombinant proteins. Today, CHO cells are the most commonly used mammalian hosts for industrial production of recombinant protein therapeutics.
Tjio J. Cell culture is the process by which prokaryotic, or eukaryotic cells are grown under controlled conditions Drug development or preclinical development is defined in many pharmaceutical companies as the process of taking a new chemical lead through the stages necessary to allow it Pre-clinical development is a stage of research that begins before Clinical trials (testing in humans can begin and during which important feasibility iterative testing and The Caco-2 cell line is an immortalized line of heterogenous human epithelial colorectal Adenocarcinoma cells developed by the Sloan-Kettering H. , Puck T. T. , Genetics of somatic mammalian cells. II. chromosomal constitution of cells in tissue culture. J. Exp. Med. 1958; 108: 259-271.
Jayapal K. P. , Wlaschin K. F. , Yap M. G. S. , Hu W-S. , Recombinant protein therapeutics from CHO cells - 20 years and counting. Chem. Eng. Prog. 2007; 103(7) 40-47.