A carcinoma is any malignant cancer that arises from epithelial cells. The Mendelian Inheritance in Man project is a Database that catalogues all the known Diseases with a genetic component, and—when possible—links them Medical Subject Headings ( MeSH) is a huge Controlled vocabulary (or metadata system for the purpose of indexing journal articles and books Malignant (from the Latin roots mal- = "bad" and -genus = "born" is a medical term used to describe a severe and progressively worsening disease Cancer (medical term Malignant Neoplasm) is a class of Diseases in which a group of cells display uncontrolled In biology and medicine epithelium is a tissue composed of cells that line the cavities and surfaces of structures throughout the body Carcinomas invade surrounding tissues and organs and may metastasize, or spread, to lymph nodes and other sites. Metastasis ( Greek: displacement μετά=next + στάσις=placement, plural metastases) sometimes abbreviated mets, A Lymph node ( lɪmf noʊd is an organ consisting of many types of cells and is a part of the Lymphatic system.
Carcinoma in situ (CIS) is a pre-malignant condition, in which some cytological signs of malignancy are present, but there is no histological evidence of invasion through the epithelial basement membrane. Carcinoma in situ (CIS is an early form of Carcinoma defined by the absence of invasion of surrounding tissues The basement membrane is a structure that supports overlying Epithelial or Endothelial cells.
Classification of carcinoma
Carcinoma, like all neoplasia, is classified by its histopathological appearance. Adenocarcinoma and squamous cell carcinoma, two common descriptive terms for tumors, reflect the fact that these cells may have glandular or squamous cell appearances respectively. Adenocarcinoma is a cancer that originates in Glandular tissue In Medicine, squamous cell carcinoma (SCC is a form of Cancer of the Carcinoma type that may occur in many different organs including the Skin See also Cancer A tumor or tumour is the name for a swelling or lesion formed by an abnormal growth of cells (termed neoplastic A gland is an organ in an animal's body that synthesizes a substance for release such as Hormones or Breast milk, often into the Bloodstream Severely anaplastic tumors might be so undifferentiated that they do not have a distinct histological appearance (undifferentiated carcinoma). Hyperplasia Hypertrophy Carcinoma Sarcoma Hyperplasia an increase in the number of cells in an organ or tissue which usually leads to an increase in the size of the tissue or organ Hypertrophy
Sometimes a tumour is referred to by the presumptive organ of the primary (eg carcinoma of the prostate) or the putative cell of origin (hepatocellular carcinoma, renal cell carcinoma). Hepatocellular carcinoma (HCC also called hepatoma) is a primary malignancy (cancer of the Liver. "Kidney Cancer" redirects here For Wilms' Tumor/Nephroblastoma see Wilms' tumor.
Types of carcinoma by ICD-O Code
(8010-8790) Epithelial
Types of lung carcinoma
- Adenocarcinoma is a malignant tumor originating in the epithelial cells of glandular tissue and forming glandular structures. In biology and medicine epithelium is a tissue composed of cells that line the cavities and surfaces of structures throughout the body In biology and medicine epithelium is a tissue composed of cells that line the cavities and surfaces of structures throughout the body In Anatomy, squamous epithelium (from Latin squama, "scale" is an Epithelium characterised by its most superficial layer consisting The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems In Medicine, squamous cell carcinoma (SCC is a form of Cancer of the Carcinoma type that may occur in many different organs including the Skin Stratum germinativum (also stratum basale or basal cell layer) is the layer of Keratinocytes that lies at the base of the epidermis immediately The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Basal cell carcinoma is a type of skin cancer It is a malignant epithelial cell tumor that begins as a papule (a small circumscribed solid elevation of the skin and enlarges peripherally developing In biology and medicine epithelium is a tissue composed of cells that line the cavities and surfaces of structures throughout the body Papilloma refers to a Benign Epithelial Tumor growing exophytically (outwardly projecting in finger-like fronds A carcinoma is any Malignant Cancer that arises from epithelial cells. An adenoma is a collection of growths (-oma of glandular origin Adenocarcinoma is a cancer that originates in Glandular tissue A gland is an organ in an animal's body that synthesizes a substance for release such as Hormones or Breast milk, often into the Bloodstream The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems An adenoma is a collection of growths (-oma of glandular origin The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Adenocarcinoma is a cancer that originates in Glandular tissue The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Linitis plastica, also known as Brinton's disease, is seen in diffuse Stomach cancer. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems An insulinoma is a Tumour of the Pancreas derived from the Beta cells which while retaining the ability to synthesize and secrete Insulin is autonomous The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems A glucagonoma is a rare Tumor of the Alpha cells of the Pancreas that results in up to a 1000-fold overproduction of the Hormone Glucagon The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems A gastrinoma is a Tumor that secretes Gastrin. It is frequently the source of the gastrin in Zollinger-Ellison syndrome. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems A VIPoma (also known as Verner Morrison syndrome, after the physicians who first described it) is a rare (1 per 10000000 per year Endocrine Tumor The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Cholangiocarcinoma is a Cancer of the Bile ducts which drain Bile from the Liver into the Small intestine. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Hepatocellular carcinoma (HCC also called hepatoma) is a primary malignancy (cancer of the Liver. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Adenoid cystic cancer (AdCC is an uncommon type of Cancer that can exist in many different body sites The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Carcinoid (also carcinoid tumour or carcinoid tumor) is a slow-growing but Malignant type of Neuroendocrine tumour, originating in the cells The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems A prolactinoma is a Benign Tumor ( Adenoma) of the Pituitary gland that produces a Hormone called Prolactin. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems An oncocytoma is a Kidney or salivary gland Tumor made up of oncocytes, a special kind of cells Presentation An oncocytoma The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems A Hürthle cell (also known incorrectly as Askanazy cell. Askanazy cells are interfollicular C-cells is an oncocytic cell in the thyroid that is often associated The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems "Kidney Cancer" redirects here For Wilms' Tumor/Nephroblastoma see Wilms' tumor. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems "Kidney Cancer" redirects here For Wilms' Tumor/Nephroblastoma see Wilms' tumor. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems The term multiple endocrine Neoplasia ( MEN) encompasses several distinct Syndromes featuring tumors of endocrine glands each with its own characteristic The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Endometrioid tumors are part of the surface epithelial Tumor group of ovarian neoplasms (10-20% of which are the endometrioid type In Anatomy, adnexa refers to the Appendages of an organ Examples of adnexa Adnexa of Eye Extraocular muscles Skin appendages are Appendages that are associated with the Skin and serve a particular function Mucoepidermoid carcinoma is the most common type of Salivary gland malignancy in children A cyst is a closed sac having a distinct membrane and Division on the nearby tissue. In vertebrates mucus is a slippery secretion produced by and covering Mucous membranes It is a viscous Colloid containing Antiseptic enzymes (such as In Physiology, the term serous fluid is used for various Bodily fluids that are typically pale yellow and transparent and of a Benign nature The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Cystadenoma (or "cystoma" refers to a type of Cystic Adenoma. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Pseudomyxoma peritonei is an uncommon Tumor known for its production of Mucus in the abdominal cavity In biology and medicine epithelium is a tissue composed of cells that line the cavities and surfaces of structures throughout the body The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Not to be confused with Wharton's duct ( Submandibular duct) Warthin's tumor or Warthin tumour, also known as papillary The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems In Medicine ( Oncology) thymoma is a Tumor originating from the Thymus. The gonad is the organ that makes Gametes The gonads in males are the Testes and the gonads in Females are the Ovaries. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Sex cord-stromal tumour is a group of tumours of Sex cord -derived tissues of the Ovary and Testis. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Thecomas or theca cell tumors are Benign ovarian neoplasms composed only of Theca cells Histogenetically they are classified as Sex cord-stromal The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Granulosa cell tumo(urs (or granulosa-theca cell tumo(urs) are Tumors of the Granulosa cell. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Sertoli-Leydig cell tumour, also known as arrhenoblastoma or androblastoma, is a member of the Sex cord-stromal tumour group of ovarian and The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Sertoli-Leydig cell tumour, also known as arrhenoblastoma or androblastoma, is a member of the Sex cord-stromal tumour group of ovarian and A paraganglioma is a rare Neoplasm that can be found in the abdomen thorax and in the head and neck region Glomus tumor was also the name formerly used for a tumor now called a Paraganglioma. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems A paraganglioma is a rare Neoplasm that can be found in the abdomen thorax and in the head and neck region The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems A phaeochromocytoma ( pheochromocytoma in the US is a Neuroendocrine tumor of the medulla of the Adrenal glands (originating in the Chromaffin The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Glomus tumor was also the name formerly used for a tumor now called a Paraganglioma. Nevus (or naevus, plural nevi, from nævus, Latin for birthmark is the medical term for sharply-circumscribed and Chronic lesions of the Melanoma is a Malignant Tumor of Melanocytes which are found predominantly in skin but also in the Bowel and the Eye (see The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems A mole, technically known as a melanocytic Nevus, is a small dark spot on human Skin. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Melanoma is a Malignant Tumor of Melanocytes which are found predominantly in skin but also in the Bowel and the Eye (see The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Melanoma is a Malignant Tumor of Melanocytes which are found predominantly in skin but also in the Bowel and the Eye (see The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Nodular melanoma (NM is the most aggressive form of Melanoma. The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems A dysplastic nevus, (or naevus; pl nevi or naevi) is an atypical mole; a mole whose appearance is different from that of common moles The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Lentigo maligna is a Melanoma In situ that consists of Malignant cells but does not show invasive growth The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Superficial spreading melanoma (SSM is the most common form of cutaneous Melanoma in Caucasians The International Classification of Diseases for Oncology (ICD-O is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems Acral lentiginous melanoma is a kind of Lentiginous skin Melanoma. Adenocarcinoma is a cancer that originates in Glandular tissue This is common in the lung (forming 30-40% of all lung carcinomas). Lung cancer is a Disease of uncontrolled Cell growth in tissues of the Lung. It is found peripherally, arising from goblet cells or type II pneumocytes. Goblet cells are Glandular simple columnar epithelial cells whose sole function is to secrete Mucus. Two types of cells contribute to the maintenance of the Alveoli of the lungs Type I and Type II pneumocytes.
- Squamous cell carcinoma due to squamous metaplasia. In Medicine, squamous cell carcinoma (SCC is a form of Cancer of the Carcinoma type that may occur in many different organs including the Skin In Anatomy, squamous epithelium (from Latin squama, "scale" is an Epithelium characterised by its most superficial layer consisting This accounts for 20-30 percent of lung tumors and is usually hilar in origin.
- Small cell carcinoma is almost certainly due to smoking. Small cell carcinoma is a type of Carcinoma usually associated with the Lung, though it can be associated with other topographies such as in Cervical cancer These metastasise early, and may secrete ADH (lowering patient sodium concentration). Arginine vasopressin ( AVP) also known as vasopressin, argipressin or antidiuretic hormone ( ADH) is a Hormone found in Sodium (ˈsoʊdiəm is an element which has the symbol Na( Latin natrium, from Arabic natrun) atomic number 11 atomic mass 22
- Large cell undifferentiated carcinomas account for 10-15 percent of lung neoplasms. These are aggressive and difficult to recognise due to the undifferentiated nature. These are most commonly central in the lung.
- Sinonasal undifferentiated carcinoma
Staging and grading
The staging of cancers is the extent of spread of the neoplasm. Grading is the system used to record the tumors degree of differentiation from the parent tissue. High grade shows little differentiation and the prognosis is therefore poor.
Carcinomas, like all cancers, are staged according to the extent of disease. The UICC/AJCC TNM system is often used, however for some common tumors, classic staging methods (such as the Dukes classification for colon cancer) are still used. The TNM Classification of Malignant Tumours ( TNM) is a Cancer staging system that describes the extent of Cancer in a patient’s body Colorectal cancer, also called colon cancer or large bowel cancer, includes Cancerous growths in the colon, Rectum and
See also
Cancer (medical term Malignant Neoplasm) is a class of Diseases in which a group of cells display uncontrolled A sarcoma (from the Greek 'sarx' meaning "flesh" is a Cancer of the connective or supportive tissue ( Bone, Cartilage, Fat Hematological malignancies are the types of Cancer that affect Blood, Bone marrow, and Lymph nodes As the three are intimately connected through Basal cell carcinoma is a type of skin cancer It is a malignant epithelial cell tumor that begins as a papule (a small circumscribed solid elevation of the skin and enlarges peripherally developing
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