Brendan Ryan may refer to:
- Brendan Ryan (Cork politician) (born 1946), Irish Indepenent (then Labour Party) Senator (1981-1993,1997-2007)
- Brendan Ryan (baseball) (born 1982), U. Brendan Ryan (born 6 August 1946) is an Irish politician and former member of Seanad Éireann for the National University of Ireland Brendan Wood Ryan (born March 26, 1982, in Los Angeles California)is a Shortstop in Major League Baseball for the St S. major league baseball player
- Brendan Ryan (Dublin politician), Irish Labour Party Senator (2007-) from Dublin
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