| Bis(trimethylsilyl)amine[1] | |
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| IUPAC name | 1,1,1,3,3,3-Hexamethyldisilazane |
| Other names | Bis(trimethylsilyl)amine Hexamethyldisilazane Hexamethyldisilane HMDS |
| Identifiers | |
| CAS number | [999-97-3] |
| SMILES | C[Si](C)(C)N[Si](C)(C)C |
| Properties | |
| Molecular formula | C6H19NSi2 |
| Molar mass | 161. IUPAC Nomenclature is a system of naming Chemical compounds and of describing the science of Chemistry in general CAS registry numbers are unique numerical identifiers for Chemical compounds Polymers biological sequences mixtures and Alloys They are also referred to A chemical formula is a way of expressing information about the Atoms that constitute a particular Chemical compound, and how the relationship between those atoms changes Molar mass, symbol M, is the Mass of one mole of a substance ( Chemical element or Chemical compound) 40 g/mol |
| Density | 0. The density of a material is defined as its Mass per unit Volume: \rho = \frac{m}{V} Different materials usually have different 76 g/cm3 |
| Melting point |
-78 °C |
| Boiling point |
125 °C |
| Hazards | |
| MSDS | External MSDS |
| NFPA 704 |
 3
1
1
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| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Bis(trimethylsilyl)amine (also known as hexamethyldisilazane, or HMDS) is a chemical reagent with the molecular formula (CH3)3Si-NH-Si(CH3)3 which consists of ammonia substituted with two trimethylsilyl functional groups. The melting point of a solid is the temperature range at which it changes state from solid to Liquid. The boiling point of a liquid is the temperature at which the Vapor pressure of the liquid equals the environmental pressure surrounding the liquid A material safety data sheet ( MSDS) is a form containing data regarding the properties of a particular substance Symbolism The four divisions are typically color-coded with blue indicating level of Health Hazard, red indicating In Chemistry, the standard state of a material is its state at 1 bar (100 Kilopascals exactly A chemical formula is a way of expressing information about the Atoms that constitute a particular Chemical compound, and how the relationship between those atoms changes Ammonia is a compound with the formula N[[hydrogen H3]] It is normally encountered as a Gas with a characteristic pungent Odor For tetramethylsilane which also abbreviated as TMS see Tetramethylsilane. In Organic chemistry, functional groups are specific groups of Atoms within Molecules that are responsible for the characteristic Chemical reactions It is a clear, colorless liquid that will hydrolize slowly upon exposure to water. Hydrolysis is a Chemical reaction during which one or more water molecules are split into hydrogen and hydroxide ions which may go on to participate in further reactions
Bis(trimethylsilyl)amide results from the deprotonation of the nitrogen atom of bis(trimethylsilyl)amines and are used as non-nucleophilic bases, including:
- Lithium bis(trimethylsilyl)amide (LiHMDS)
- Sodium bis(trimethylsilyl)amide (NaHMDS)
- Potassium bis(trimethylsilyl)amide (KHMDS)
Contents |
Organic chemistry
One of the uses of HMDS is as a reagent in condensation reactions of heterocyclic compounds such as in the microwave synthesis of a derivative of xanthine:[2]
Other
In photolithography, HMDS is often used in as an adhesion promoter for photoresist. Deprotonation is a Chemistry term that refers to the removal of a Proton ( Hydrogen Cation H+ from a Molecule, forming Nitrogen (ˈnaɪtɹəʤɪn is a Chemical element that has the symbol N and Atomic number 7 and Atomic weight 14 As the name suggests a non-nucleophilic base is an organic base that is a very Strong base but at the same time a poor Nucleophile. Lithium bis(trimethylsilylamide is the Chemical compound with the formula ((CH33Si2NLi Sodium bis(trimethylsilylamide is the Chemical compound with the formula ((CH33Si2NNa Parameters work only in their own section When a parameter is not needed please leave it empty when a parameter is wrong just clear A reagent or reactant is a substance or compound consumed during a Chemical reaction. A condensation reaction is a Chemical reaction in which two Molecules or moieties ( Functional groups) combine to form one single molecule together with Microwave chemistry is the science of applying Microwave irradiation to chemical reactions. In Chemistry, a derivative is a compound that is formed from a similar compound or a compound that can be imagined to arise from another compound if one Xanthine (ˈzænθiːn ˈzænθaɪn] (37-dihydro-purine-26-dione is a Purine base found in most body tissues and fluids and in other organisms Photolithography (also called optical lithography) is a process used in Microfabrication to selectively remove parts of a thin film (or the bulk of a substrate Photoresist is a Light -sensitive material used in several industrial processes such as Photolithography and Photoengraving to form a patterned coating Best results are obtained by applying HMDS from the gas phase on heated substrates. [3]
In electron microscopy, HMDS can be used as an alternative to critical point drying during sample preparation. An electron microscope is a type of Microscope that uses Electrons to illuminate a specimen and create an enlarged image [4]
See also
References
- ^ Merck Index, 13th Edition, 4708. Hexamethyldisiloxane is a Chemical compound with the formula O2
- ^ Burbiel JC, Hockemeyer J, Müller CE (2006). "Microwave-assisted ring closure reactions: synthesis of 8-substituted xanthine derivatives and related pyrimido- and diazepinopurinediones". Beilstein J Org Chem 2: 20. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 17067400.
- ^ Cornell NanoScale Science & Technology Facility. CNF - Photolithography Resist Processes and Capabilities. Retrieved on 2008-01-29. 2008 ( MMVIII) is the current year in accordance with the Gregorian calendar, a Leap year that started on Tuesday of the Common Events 904 - Sergius III comes out of retirement to take over the papacy from the deposed Antipope Christopher.
- ^ Bray DF, Bagu J, Koegler P (1993). "Comparison of hexamethyldisilazane (HMDS), Peldri II, and critical-point drying methods for scanning electron microscopy of biological specimens". Microsc. Res. Tech. 26 (6): 489–95. doi:. A digital object identifier ( DOI) is a permanent identifier given to an Electronic document. PMID 8305726.