Biological activity - Citizendia

Pharmacological or biological activity is an expression describing the beneficial or adverse effects of a drug on living matter. Pharmacology (from Greek grc φάρμακον pharmakon, "drug" and grc -λογία -logia) is the study of how Drugs A drug, broadly speaking is any chemical substance that when absorbed into the body When the drug is a complex chemical mixture, this activity is exerted by the substance's active ingredient or pharmacophore but can be modified by the other constituents. An active ingredient ( AI) also active pharmaceutical ingredient ( API) or bulk active, is the substance in a drug that is Pharmaceutically A pharmacophore was first defined by Paul Ehrlich in 1909 as "a molecular framework that carries ( phoros) the essential features responsible for a The main kind of biological activity is a substance's toxicity. Toxicity is the degree to which a substance is able to damage an exposed organism Activity is generally dosage-dependent and it is not uncommon to have effects ranging from beneficial to adverse for one substance when going from low to high doses. Activity depends critically on fulfillment of the ADME criteria. ADME is an Acronym in Pharmacokinetics and Pharmacology for '''a'''bsorption, '''d'''istribution, '''m'''etabolism

Whereas a material is considered bioactive if it has interaction with or effect on any cell tissue in the human body, pharmacological activity is usually taken to describe beneficial effects, i. The cell is the structural and functional unit of all known living Organisms It is the smallest unit of an organism that is classified as living and is often called The human body is the entire physical and mental structure of a Human Organism. e. the effects of drug candidates. In Medicine, Biotechnology and Pharmacology, drug discovery is the process by which drugs are discovered and/or designed

In the study of biomineralisation, bioactivity is often meant as the formation of calcium phosphate deposits on the surface of objects placed in simulated body fluid, a buffer solution with ion content similar to blood. Biomineralisation is the process by which living organisms produce minerals often to harden or stiffen existing tissues Calcium phosphate is the name given to a family of Minerals containing Calcium Ions (Ca2+ together with orthophosphates (PO43- For an individual weak acid or weak base component see Buffering agent. Blood is a specialized Bodily fluid that delivers necessary substances to the body's cells ��such as nutrients and oxygen—and transports Waste products

Lipinski's Rule of Five is a Rule of thumb to evaluate Druglikeness, or determine if a Chemical compound with a certain pharmacological or Quantitative structure-activity relationship (QSAR is the process by which Chemical structure is quantitatively correlated with a well defined process such as A chemical property is any of a material's properties that becomes evident during a Chemical reaction; that is any quality that can be established only by changing a substance's Molecular properties include the chemical properties, physical properties, and structural properties of Molecules including Drugs A physical property is any aspect of an object or substance that can be measured or perceived without changing its identity. Chemical structure refers to Molecular geometry, Electronic structure and Crystal structure.

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