Sayyid ‘Ali Hamadani was a Persian physician who lived before 1546 CE and was from Hamadan. Hamedān or Hamadān ( Persian: همدان, Old Persian: Hagmatana Hebrew: המזיין Ancient Greek: Ecbatana)
Sayyid Ali Hamdani composed a brief Persian essay on physiognomy titled Risalah-i qiyafah which is preserved in a unique copy now at the United States National Library of Medicine. Physiognomy ( Gk physis, nature and gnomon, judge interpreter is the assessment of a person's character or personality from their outer appearance especially The United States National Library of Medicine ( NLM) operated by the United States federal government, is the world's largest Medical library. The essay must have been written before 1546, when the copy was made.
The author is otherwise unknown, and nothing is known of his life.