Alfred George Knudson, Jr. M. D. , Ph. D. (born in Los Angeles, 1922) is a geneticist specialised in the genetics of cancer. Los Angeles (lɑˈsændʒələs los ˈaŋxeles in Spanish) is the largest City in the state of California and the American West Year 1922 ( MCMXXII) was a Common year starting on Sunday of the Gregorian calendar. Genetics (from Ancient Greek grc-Latn genetikos, “genitive” and that from grc-Latn genesis, “origin” a discipline of Biology, is Cancer (medical term Malignant Neoplasm) is a class of Diseases in which a group of cells display uncontrolled Probably the most important one of his many contributions to the field was the formulation of the Knudson hypothesis in 1971, which explains the effects of mutation on carcinogenesis (the development of cancer). The Knudson hypothesis is the Hypothesis that Cancer is the result of accumulated Mutations to a cell's DNA. In biology mutations are changes to the Nucleotide sequence of the Genetic material of an organism Carcinogenesis (meaning literally the creation of Cancer) is the process by which normal cells are transformed into cancer cells
Born in Los Angeles in 1922, Knudson received his B. S. from California Institute of Technology in 1944, his M. D. from Columbia University in 1947 and his Ph. D. from California Institute of Technology in 1956. He held a Guggenheim fellowship from 1953 to 1954. He has been affiliated with the Fox Chase Cancer Center in Philadelphia since 1976. The Fox Chase Cancer Center is a National Cancer Institute -designated Comprehensive Cancer Center research facility and hospital located in the Fox Chase Philadelphia (ˌfɪləˈdɛlfiə
He received numerous prizes and honorary doctorates for his work, most prominently the 1998 Albert Lasker Award for Clinical Medical Research. Year 1998 ( MCMXCVIII) was a Common year starting on Thursday (link will display full 1998 Gregorian calendar) The Lasker~DeBakey Clinical Medical Research Award is awarded by the Lasker Foundation for the understanding diagnosis prevention treatment and cure of disease He also received the 1999 American Society of Pediatric Hematology/Oncology (ASPHO) Distinguished Career Award and the 2005 American Association for Cancer Research (AACR) Award for Lifetime Achievement in Cancer Research. Year 1999 ( MCMXCIX) was a Common year starting on Friday (link will display full 1999 Gregorian calendar) Year 2005 ( MMV) was a Common year starting on Saturday (link displays full calendar of the Gregorian calendar. The American Association for Cancer Research (AACR is the world's oldest and largest professional organization dedicated to advancing cancer research
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