Acetanilide
IUPAC name	N-phenylacetamide
Identifiers
CAS number	[103-84-4]
SMILES	O=C(C)Nc1ccccc1
Properties
Molecular formula	C8H9NO
Molar mass	135. IUPAC Nomenclature is a system of naming Chemical compounds and of describing the science of Chemistry in general CAS registry numbers are unique numerical identifiers for Chemical compounds Polymers biological sequences mixtures and Alloys They are also referred to A chemical formula is a way of expressing information about the Atoms that constitute a particular Chemical compound, and how the relationship between those atoms changes Molar mass, symbol M, is the Mass of one mole of a substance ( Chemical element or Chemical compound) 17 g/mol
Density	1. The density of a material is defined as its Mass per unit Volume: \rho = \frac{m}{V} Different materials usually have different 219 g/cm³
Melting point	113–115 °C (235–239 °F)
Boiling point	304 °C
Solubility in water	0. The melting point of a solid is the temperature range at which it changes state from solid to Liquid. The boiling point of a liquid is the temperature at which the Vapor pressure of the liquid equals the environmental pressure surrounding the liquid Solubility is the characteristic Physical property referring to the ability of a given substance the Solute, to dissolve in a Solvent. Water is a common Chemical substance that is essential for the survival of all known forms of Life. 1 g/100 mL at 22°C
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Acetanilide^[1] is an odourless solid chemical of leaf or flake-like appearance. In Chemistry, the standard state of a material is its state at 1 bar (100 Kilopascals exactly A solid' object is in the States of matter characterized by resistance to Deformation and changes of Volume. It is also known as N-phenylacetamide, acetanil, or acetanilid, and was formerly known by the trade name antifebrin. A trade name, also known as a trading name or a business name, is the name which a Business trades under for commercial purposes although its registered

Contents 1 Formation 2 Properties 3 Applications 4 Notes 5 External links

Formation

Acetanilide can be produced by reacting acetic anhydride with either aniline or phenylammonium chloride

Properties

This compound is soluble in hot water. Acetic anhydride is the Chemical compound with the formula (CH3CO2O Aniline, phenylamine or aminobenzene is an Organic compound with the formula C6H7N Aniline, phenylamine or aminobenzene is an Organic compound with the formula C6H7N It has the ability to self-ignite if it reaches a temperature of 545 °C, but is otherwise stable under most conditions^[2]. The Celsius Temperature scale was previously known as the centigrade scale. Pure crystals are plate shaped, white in colour, and have a sugary aftertaste.

Applications

Acetanilide is used as an inhibitor in hydrogen peroxide and is used to stabilize cellulose ester varnishes. A reaction inhibitor is a substance that decreases the rate of or prevents a Chemical reaction. Hydrogen peroxide (H2O2 is a very pale blue liquid which appears colorless in a dilute solution slightly more Viscous than water Cellulose is an Organic compound with the formula, a Polysaccharide consisting of a linear chain of several hundred to over ten thousand β(1→4 Esters are a class of Chemical compounds and Functional groups Esters consist of an inorganic or organic Acid in which at least Varnish is a transparent, hard protective finish or film primarily used in Wood finishing but also for other materials It has also found uses in the intermediation in rubber accelerator synthesis, dyes and dye intermediate synthesis, and camphor synthesis. A dye can generally be described as a Colored substance that has an affinity to the substrate to which it is being applied } Camphor is a waxy white or transparent solid with a strong aromatic odor Acetanilide was used as a precursor in penicillin synthesis and other pharmaceuticals and its intermediates. Penicillin (sometimes abbreviated PCN or pen) is a group of Beta-lactam antibiotics used in the treatment of Bacterial Infections

Acetanilide has analgesic and antipyretic (fever-reducing) properties; it is in the same class of drugs as acetaminophen (paracetamol). Antipyretics are Drugs that reduce body temperature in situations such as Fever. Fever (also known as pyrexia, from the Greek pyretos meaning fire or a febrile response, from the Latin word Febris Paracetamol ( INN) (ˌpærəˈsiːtəmɒl -ˈsɛtə- or acetaminophen ( USAN) is a widely-used Analgesic and Antipyretic Medication Under the name acetanilid it formerly figured in the formula of a number of patent medicines and over the counter drugs. Patent medicine is the somewhat misleading term given to various medical Compounds sold under a variety of names and labels though they were for the most part actually In 1948, Julius Axelrod and Bernard Brodie discovered that acetanilide is much more toxic in these applications than other drugs, causing methemoglobinemia and ultimately doing damage to the liver and kidneys. Year 1948 ( MCMXLVIII) was a Leap year starting on Thursday (link will display the 1948 calendar of the Gregorian calendar. Julius Axelrod ( May 30, 1912 &ndash December 29 2004) was an American biochemist. Methemoglobinemia is a disorder characterized by the presence of a higher than normal level of Methemoglobin (metHb in the Blood. The liver is a vital organ in the human body and is present in Vertebrates and some other animals The kidneys are complicated organs that have numerous biological roles As such, acetanilide has largely been replaced by less toxic drugs, in particular acetaminophen, which is a metabolite of acetanilide and whose use Axelrod and Brodie suggested in the same study. Metabolomics is the "systematic study of the unique chemical fingerprints that specific cellular processes leave behind" - specifically the study of their small-molecule metabolite

In the 19th century it was one of a large number of compounds used as experimental photographic developers. The 19th century of the Common Era began on January 1, 1801 and ended on December 31, 1900, according to the Gregorian calendar In Film developing, photographic developer (or just developer) is a chemical that makes the Latent image on the film or print visible

Notes

External links

• Acetanilide MSDS

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